“highly significant”

There was a highly significant increase in BMS scores for drug‐treated mice versus vehicle beginning at week 1 (4.2 ± 1.2 versus 0.2 ± 0.1; p < 0.0001).

These differences were highly significant ( p < 0.0001), suggesting greater susceptibility to hypercoagulability in males. 3.4.

In addition, a highly significant association ( p <0.0001) was observed between weight gain and the number of cigarette-free days.

An analysis of variance of the factor score variances was statistically highly significant ( P < 0.0001) indicating that a large amount of the periodic variability could be explained by the variances in the physiochemical attribute factor scores.

The difference in frequencies of variants within cline centre groups between the filtered (SCV only) and unfiltered datasets was highly significant (European taurine S1: Χ 2 = 13,151, df = 2; p < 0.0001; African taurine S1: Χ 2 = 17,118, df = 2; p < 0.0001), indicating an enrichment of variants with restricted gene flow and unbiased introgression.

ANOVA results ( Table 2 ) confirmed the quadratic model was highly significant ( F = 84.06, p < 0.0001).

We repeated this 2500 times to build a null distribution of Δβ, and calculated the proportion with equal or stronger reductions for a one-tailed p-value, which was highly significant (p<0.0001).

However, sheep showed a highly significant association with BT cases (IRR = 155.53, 95% CI: 20.02–1208.25, p < 0.0001), indicating that sheep have a much higher risk of contracting BT compared to cattle.

All group comparisons were highly significant ( p <0.0001).

There was a highly significant increase (p < 0.0001) in both total and neutrophil leukocyte number associated with each stage of COPD, in accordance with the GOLD classification.

Overall, there was a highly significant correlation between these lymphoid structures and HEV density in the extra-tumoral areas ( Fig. 2e : p < 0.0001, R 2 = 0.442).

pistillata corals remained highly significant when comparing across treatments and sites ( p < 0.0001) (Fig. 2E ).

For human genes, highly significant differences were found between G1 and G2 (F = 1.29; p <0.0001), G1 and G3 (F = 1.33; p <0.0001), or G1 and G4 exons (F = 1.33; p <0.0001), while none was found between G2 and G3 (F = 1.04; p = 0.4254), G2 and G4 (F = 1.03; p = 0.4285), or G3 and G4 exons (F = 1.00; p = 0.9243).

Our measurements showed that MCF-10A had a small, yet highly significant, preference to grow on 2D conditions compared to control 3D ECMs (1.1 fold, with P < 0.0001) or tumor-associated 3D ECMs (1.3 fold, P < 0.0001).

There was a highly significant difference between the EFG and CG with p = 0.0001 ( p < 0.01).

In this analysis, group differences in subjective pain scores were highly significant before controlling for the effect of anterior cingulate cortex activation ( F = 38.0, P <0.0001); a finding that was reversed ( F = 1.8, P = 0.195) when removing (regressing out) this effect.

At 0–6 m, hippocampal loss in mild cognitive impairment and Alzheimer's disease was already highly significant ( P < 0.0001), whereas the loss in normal became significant in the 0–12 m interval only ( P = 0.005).

However, during the second and third weeks, animals maintained at 21°C consumed on average 21.5% more than animals housed at 32°C, but despite this highly significant difference in ingested food ( p < 0.0001), only the warmed animals gained a significantly greater amount of weight.

Regression analyses (not shown) demonstrated a highly significant association between numbers of breakpoints vs. chromosome length ( p < 0.0001) and numbers of breakpoints vs. gene content ( p = 0.0001) at univariable analyses.

The difference between the frail group and the others is highly significant [ p < 0.0001 by Mann–Whitney U -test (MWU)].

A Mantels test for matrix correspondence between pair-wise genetic ( D AS ) and geographic distance (km) revealed a highly significant positive correlation between these two measures (R XY = 0.394, p<0.0001, Figure 3 ).

This was supported by highly significant group × trial interactions (path lengths: F 160,3360 = 1.69, p < 0.0001; search preference: F 40,840 = 2.28, p < 0.0001).

In fact, it was observed a highly significant (p < 0.0001) difference between the controls and MM or between MGUS and MM, while no significance was found between controls and MGUS groups (p = 0.95) by means of a two by two comparison of the three groups (controls, MGUS and MM) concerning the distribution of K- ras gene mutation, Interestingly, significant increases (P = 0.02) of serum bFGF levels were observed in patients showing K- ras gene mutation (median = 4.6 pg/ml; range = 1.2–19.6 pg/ml) as compared with those in which the gene was in the wild type form (median = 2.2 pg/ml; range = 1.0–20.8 pg/ml).

Similarly, all non-constant terms in a cubic regression of onset age on number of repeats were highly significant (p<0.0001), and the overall F-test for comparing the cubic model to a constant-age-of-onset model had a p-value of 4.4e-15.

The differences where highly significant in the Wilcoxon test (z = -3,79; p < 0,0001).