In contrast, a highly significant negative correlation was detected between the frequency of mucosal CD3 − CD20 − TGF-β + cells and CD4 + T cells in SIV infected animals ( r = −0.582, p < 0.0001, Figure 3 E). 3.4.
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However, age showed a highly significant association ( P < 0.0001).
The Ct values attained for the SARS-CoV-2 E gene using the AGPC method showed a highly significant correlation to those reported for the Cobas ® 6800 system (r = 0.97, p<0.0001) and the Maxwell ® instrument (r = 0.98, p<0.0001).
Median emPHasis-10 scores were 3, 19, 31 and 40 in WHO functional classes I, II, III and IV, respectively, with highly significant differences between the scores in each functional class (all p<0.0001).
Differences between the two inhalers in PIF were highly significant in all five study groups (p ≤ 0.0001), while statistical significance (p < 0.05) was observed with maximum ∆P in the four patient groups.
In numbers, the reduced expression in ME-CFs compared to ACFs range from rather insignificant 87% down to highly significant 15% ( p ≤ 0.0001), while all ME-CSCs showed a significant upregulation between 55 and twofold compared to ACSCs ( p ≤ 0.001).
In a repeated measures ANOVA analysis this was highly significant ( P <0.0001) for a genotype effect on lean mass in grams in males and females ( Fig. 3B and Table 2 ).
These changes were highly significant ( p < 0.0001) and concentration-dependent, being observable at day 7 of differentiation, in particular regarding CD11b expression ( Figure 2 F,G; Figure S3F,G ).
This result of zero overlapping genes given these two groups is highly significant ( p value < 0.0001) indicating that this result was not due to chance.
The Log rank test indicated highly significant differences in survival among the three groups (p < 0.0001).
We identified a highly significant difference of the mean scores between the groups with a p -value of <0.0001.
The greatest mean IOP change was found in Group A, with a highly significant mean IOP change of -7.4 ± 3.8 mmHg (-29.7%) at week 1, -8.0 ± 3.3 mmHg (-32.0%) at month 1, and -8.0 ± 3.7 mmHg (-32.0%) at month 3 (all P < 0.0001 compared with baseline).
ANOVA revealed a highly significant main effect of condition. with maximum in the lower gamma range at 30–45 Hz (p<0.0001, Fig. 3 ).
All the Procrustes tests were highly significant ( P = 0.0001 in all cases; see table S3), indicating a strong correspondence between the complete and imputed functional spaces; consequently, we used the PCA based on imputed trait data in the rest of analyses.
The same was 6.56 (sd-4.16) after intervention, and the difference was highly significant (paired t -test t value = 15.99, P < 0.0001) [ Table 2 ].
Notably, when comparing RIG_LDH-GA CM to RIG CM, the reduction in OC number was highly significant ( p < 0.0001) at all doses except the lowest one.
They observed highly significant association of seven COMT marker haplotypes with schizophrenia (CLUMP T4 P -value = 0.0001).
Conversely, we observed in the Ptch1 +/− /Btg1 KO MBs a highly significant increase in the percentage of caspase-3-positive cells to the total number of cells (apoptotic index), with respect to the Ptch1 +/− /Btg1 WT tumors ( p < 0.0001 and 42% increase; Mann–Whitney U -test; Figures 1C,D ).
In the conventional group, postoperative corneal endothelial cell loss was highly significant with p < 0.0001, after 4 and 12 weeks.
An additional indication that the cluster analysis was rather successful is that, despite the high (.49-.68) pairwise correlations of the three EMP data set variables, except for the first two clusters (CLE1 and CLE2) the Bartlett test of overall independence was not significant or just marginally significant, whereas in the total sample the test was highly significant ( p < .0001).
A subgroup comparison consisting of all age- and sex-matched controls also demonstrated highly significant difference between HGPS (progerin, 34 512±14 432 pg/mL; n=25) and non-HGPS control levels (progerin, 377±226 pg/mL; n=13; P <0.0001).
On the other hand, the correlation of the MCQ scores with those obtained in the VP exam was highly significant (r = 0.452, p < 0.0001).
In all ages, a difference between Gnrh1 expression in the controls and knockout groups was highly significant (P< 0.0001).
The comparison between PBS and US16 showed a highly significant difference ( P < 0.0001), as did the comparison between PBS and US16.1 ( P < 0.0001), indicating a marked difference in pixel intensity values between these groups.
In our study, we found a statistically highly significant correlation between the degree of fibrosis and the NFS score ( p <0.0001, chi -square and Fisher’s exact tests) (Table 6 ).