The difference between the treatments was marginally significant at Day 4 and 7 (P = 0.0532 and 0.0560, respectively), and highly significant by Day 14 (P < 0.0001; Fig 5D ).
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However, the permutation test with 1000 random window sets was highly significant in all combinations ( p < 1 × 10 − 4 ).
This performance is further strengthened by highly significant p -values (2LOmb’s global p -value < 0.0001) and the presence of common SNPs among some or all SNP pairs that are parts of three- and four-locus interactions in the 2LOmb results.
Although differentiation among subgroups was highly significant (P<0.0001), 76.95% of total genetic variance was attributed to the difference within subgroups and 1.51% within individuals.
In each subject the proportion of variance explained was superior in the non-shuffled data and this difference was highly significant (Wilcoxon signed rank test, all p values <.0001).
It was noticed that there were strong positive linear correlations between the three imaging modalities concerning density measures: r = 0.95 (MRI and DBT), r = 0.97 (FFDM and DBT), and r = 0.87 (FFDM and MRI), with highly significant differences between FFDM and DBT/MRI ( p < 0.0001) but no significant differences between DBT and MRI ( p > 0.05).
The diminution seen was highly significant ( p < 0.0001) as determined by paired Wilcoxon signed-rank sum test.
Both predictors are highly significant ( p < 0.0001 ).
Adhesion Protocol Comparisons In comparisons of different adhesion protocol groups for each RBC, there were highly significant differences between and among groups for all RBCs: FOBF ( F =266.87, P <0.0001), TNCBF ( F =173.16, P <0.0001), and Z350XT ( F =103.64, P <0.0001).
However, a highly significant and strong correlation ( p < 0.0001) was found between the number of nuclei per OC and the percent eroded surface per bone surface in vitro ( Figure 4 b).
The model F-value of 178.56 indicated that the model was highly significant at p < 0.0001.
While both 24 h and 1+23 treatment paradigms resulted in substantial loss of hair cells, there was nevertheless a large and highly significant difference between these treatments (Tukey's multiple comparison, p < 0.0001).
ANOVA analysis ( Table S2 ) shows that the quadratic regression model was highly significant ( p -value > F-value: F-value = 24.18 and p -value = 0.0001) and reliable (Std.
We found that, within each scale at 10 h APF, a highly significant difference ( t test for two-independent samples; p < 0.0001) between actin-bundle areas was found.
The a priori defined primary pharmacodynamic outcome of an increase in the frequency of Tregs as a percentage of CD4 + T-lymphocytes at D8 was dose-dependent (JT-J test, p < 0.0001) and highly significant for both treated arms (MW-U test, p < 0·0001; 2 MIU: mean [SD]: +6·2% [2·2]; 1 MIU: mean [SD]: +3·9% [1·2]) as compared to placebo (mean [SD]: −0·5% [1·3]) (see Table 3 , Fig. 2 a and b).
We found not only a highly significant difference between the two groups (p ****<0.0001; Fig. 2 I) but also an excellent receiver operating characteristic (AUROC 0.9955; 95% CI [0.9854–1.000]; ****p < 0.0001; Fig. 2 J). 3.2.
Mann–Whitney U test revealed that 11 of 13 phyla (except Actinobacteriota and Nitrospirota) showed highly significant differences between rhizosphere and bulk soils ( Table S2 : **** p < 0.0001).
This was a highly significant ( P < 0.0001) difference.
All independent variables for each vertebrate genus were highly significant ( p < 0.0001) in the model, except for Apodemus ( p = 0.0755).
T category The statistical comparison of the frequency of superficial tumours (Tis, Ta and T1) and muscle invasive tumours (≥ T2) in the Hamburg study population with the data of the RKI showed a highly significant increase ( P < 0.0001) in the incidence of muscle invasive tumours in SCI patients (Fig. 4 ).
Finally, as in our gene-expression data, we observed highly significant correlations between the intra-tumoral cell counts of the myeloid and main (T, B or NK cells) lymphoid subset ( Figure 3 j-o, p < .0001).
The increased endurance time was highly significant (p<0.0001) and the significance was evident already from 6 weeks.
Siebert et al , 16 reported a highly significant difference in tibiofemoral alignment between the two groups (RA: 1/70, 1.4% [4° deviation from planned angle] vs CM: 18/52, 35% [deviation >3°- 7°]; p<0.0001).
A moderate and highly significant correlation was observed at ages 3·5 years and 5 years for total carbohydrate ( r = 0·39; P < 0·0001), total sugar ( r = 0·39; P ≤ 0·0001) and starch intakes ( r = 0·41; P ≤ 0·001).
A highly significant ( p < 0.0001) positive correlation was identified for the %DevLep with CCL4 WCS and a negative correlation for %SSS with S100A12 Med and S100A12 WCS ( Supplementary Table 1 ).