“highly significant”

As expected, LPS induced a highly significant increase of nitrites production by BV2 cells (Fig. 5 a; P < 0.0001).

Statistical analysis showed that there was a highly significant negative correlation between ADAR1 and Smad4 in these samples ( p < 0.0001) (Fig. 8 g).

These differences were highly significant ( p < 0.0001).

The average fasting blood glucose of pregnant ladies who lives in Abha (high altitude) was 72.5 ± 7.5 mg/dl and this was lower than the average fasting blood glucose of participants from Muhayil Aseer (low altitude) which was found to be 77.9 ± 5.7 mg/dl, this difference was reported to be highly significant ( P value = 0.0001) [ Table 2 ].

During the initial 6 months of the study, the cyclosporine A group had consistently lower IOP than the betamethasone group, which was statistically highly significant ( P < 0.0001).

The results in Table 1 showed a highly significant increase in oral body temperature among the exposed group (the bakers) compared to the control group (p < 0.0001).

truncatus consistently and reproducibly correlated with snails showing highly significant (up to P < 0.0001) decrease in soft tissue and hemolymph content of the monounsaturated fatty acid, oleic acid, and the polyunsaturated fatty acids, linoleic, and arachidonic acids as compared to naïve snails.

Data were considered statistically significant at p < 0.05 (* p < 0.05, significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; **** p < 0.0001, extremely significant). 3.

Results Nematode egg counts The FEC showed a highly significant (P<0.0001) seasonal pattern, with the highest values observed in calves after they had been on pasture for eight weeks.

For the cabbage diallel study, there were highly significant differences (P < 0.0001) among the genotypes, and based on this result, the user can proceed with interpretation of results from other analyses proposed by Hayman ( 1954b ).

Optimization by Box–Behnken (BB) design Using inoculum size (E), temperature (F), and initial pH (H) as independent variables and inhibition rate (Y) as the response, a quadratic regression model was obtained with Design-Expert 13.0: .ANOVA demonstrated that the regression model was highly significant (P < 0.0001), with an R2 of 0.9928, indicating that 99.28% of the variation could be explained by the model.

The highly significant positive phenotypic correlation between NCPP and SPP ( r = 0.90, p < 0.0001) and the negative correlation between those traits and TSW ( Table S4 ), may indicate compensation between yield components via morphological modifications [ 7 ].

In a univariate logistic regression, we observed a highly significant positive association between the composite index score and the likelihood of aflatoxin detection (OR 1.6, p < 0.0001).

The negative correlation between burden and RANTES fold change was highly significant (Fig. 5 c, Pearson r = − 0.27, p < 0.0001).

Once again, Gnetin C exhibited the most profound effects in both cell lines and highly significant inhibition of cell migration ( p < 0.0001) compared to Res and Pter ( Figure 3 C,D). 3.3.

The AMP concentrations evaluated here revealed 97% to 99% cell viability; the opposite effect was observed in DMSO-treated cells (12% viability), having highly significant differences (p < 0.0001) when comparing the concentrations evaluated here ( Fig. 7 ).

wound infection biofilm antimicrobial antiseptic hypochlorous acid human plasma biofilm model wound irrigation chronic wound internal grant program of the Faculty of Health at Witten/Herdecke University, Germany IFF2018-61 German “Initiative Chronische Wunde e.V.” (ICW e.V.) Both reference substances, OCT/PE and PHMB-based irrigation solution, achieved a highly significant reduction of P. aeruginosa (4.77 ± 1.41 and 5.25 ± 0.93 log 10 steps, respectively; p < 0.0001), S. aureus (6.18 ± 0.00 and 4.82 ± 1.36 log 10 steps; p < 0.0001), and MRSA (both 6.18 ± 0.00 log 10 steps; p < 0.0001) within 30 min of exposure ( Figures 2A – C ).

For stem diameter, the Treatment effect was not significant across corrections (Greenhouse–Geisser: MS = 6.23, F = 1.27, p = 0.332), but the effect of Time was highly significant (MS = 83.02, F = 123.96, p < 0.0001), showing consistent increases in stem diameter across weeks.

The perindopril trials demonstrated a highly significant event reduction (OR 0.78; 95% CI: 0.72–0.85; p < 0.0001 (Fig. 4) .

The ROC analysis (sensitivity and specificity; Table 3 ) revealed that a highly significant ( p < 0.0001) difference between two medians with a large effect size does not necessarily represent a good classifier, even if the effect size is proportional to the AUC.

Indeed, based on this ratio, fim2 expression in HB101 exerted a highly significant positive impact on biofilm formation on both surfaces ( P < 0.0001 in each case).

The associations remained significant for both KIR2DS2 (p = 0.0083 p c = 0.1162; OR = 2.06; 95%CI = 1.2–3.4) and KIR2DS3 (p = 0.0008 p c = 0.0112; OR = 2.37; 95%CI = 1.4–3.9), and the KIR profile composed of all three genes was also highly significant, showing an even higher OR (p < 0.0001 p c = 0.0014; OR = 3 95%CI 1.8–4.7).

RNAs Co-expression and Interaction Network The co-expression network of the most highly significant DEGs ( p ≤ 0.0001) was constructed to identify the potential DEGs interaction by using GeneMANIA tool ( 32 ).

After day 42 after infection, the difference in CD4 + memory T cell proliferative frequencies between RMs destined for normal versus rapid progression was highly significant (P < 0.0001 by t test).

The difference in the mean value of the PPY is highly significant ( p < 0.0001) and higher for the high-volume publishers.