“highly significant”

The difference between PBS and fixed samples (formalin and PAXgene) was highly significant (p < 0.0001) but also between PAXgene and formalin (p < 0.05).

2D showed that induced cell migration by synthetic activation of PI3K is statistically highly significant (p<0.0001), while endogenous activation of Rac does not cause a significant increase in cell migration.

Estramustine phosphate did not produce significant increases in CK18-Asp396 ( P =0.13), whereas highly significant increases in total CK18 were observed ( P <0.0001).

Notably, TG7 and TG1 exhibit a highly significant increase in gene expression compared to normal human testes ( n = 3, **** p < 0.0001).

Genotypic differentiation between the two populations was highly significant overall ( P <0.0001), as well as for four out of the seven loci (JS183, JS188, SKTg19, and SKTg22; Table 1 ).

There are highly significant (P<10 –4 ) differences in BAS Naming Vocabulary Score between groups, with both sub-fertile and ART groups having higher mean scores than the controls.

Statistical analysis (ANOVA, p < 0.05) revealed highly significant differences ( p < 0.0001 for most pathogens, and p = 0.003 for Morganella morganii ) in biofilm formation among the untreated control, hibiscus-treated, and prune-treated groups for nearly all the examined isolates.

Perhaps due to divergent trajectories with age of TLs in HSCs versus male germ cells, the correlation we observed between sperm TL and LTL, although highly significant ( P = 0.0001), is much weaker ( r = 0.33) than has been observed among somatic tissues, ( Benetos et al. , 2011 ; Granick et al. , 2011 ; Smith et al. , 2011 ).

These differences in fibrinogen concentrations among blood groups were highly significant ( p < 0.0001), suggesting blood type may have an influence on fibrinogen levels in COVID-19 patients.

This difference was highly significant (p-value < 0.0001).

A permutation test with 283 isolates belonging to a cluster showed highly significant temporal clustering of Campylobacter spp. isolates of identical genotype (p<0.0001).

Both the formulation and the artificial saliva and the interaction of the two variables have a highly significant effect on all continuous rheological parameters ( p < 0.0001, two-way ANOVA) ( Table S2 ).

On the 9th day, a highly significant difference was observed between the control and CCl 4 groups ( p < 0.0001).

This was a highly significant difference ( p < 0.0001) compared to the age-matched hSOD1-WT mice ( Figure 6 B).

Notably, the combination treatment resulted in the most pronounced improvement with a highly significant reduction in TC, LDL and TG ( p < 0.0001) and a marked increase in HDL ( p < 0.001) (Fig. 8 ).

The treatment difference of 14.1% (95% CI 8.2, 19.2) was highly significant ( P < 0.0001).

Parameter estimate for t-1 was 0.74, and this relationship was highly significant (p < 0.0001).

There was a highly significant ( p < .0001) difference in clinicians’ knowledge transfer questionnaire scores pre- and post-educational session.

5d ) were highly predictive of dhurrin concentration owing to a marginally significant additive (linear model coefficient estimate t = –2.18, P = 0.03) and highly significant quadratic ( t = 4.97, P < 0.0001) effect on untransformed dhurrin levels.

OMP treatment reduced TGF-β1 levels to 180.7 ± 2.82 pg/mg protein, whereas GLY-NPs dropped it further, to 90.83 ± 2.41 pg/mg protein, with all intergroup comparisons being highly significant ( p < 0.0001) ( Figure 8 A).

Overall there was a highly significant difference between the two groups of donors as determined by two‐way ANOVA ( p < 0.0001) (Fig. 3 ).

Evaluation by the Fischer’s exact test revealed that only the affected (n = 12) and not the unaffected twins (n = 0) had autoantibodies against the systemic autoantigen targets, and this difference was highly significant (P < 0.0001).

Each term in the model (coverage, month, and region) was highly significant ( P < 0.0001) and provided significant explanatory power [ 16 ].

Friedman’s test proved that the effect of the stimulus on perceived fear was highly significant (chi-square = 6130.252, df = 41, P < 0.0001).

The fat-graft group also showed highly significant differences when compared with the groups submitted to the sternocleidomastoid muscle flap ( p = 0.0001) and the platelet-rich fibrin gel techniques ( p = 0.016).