“highly significant”

The AMP concentrations evaluated here revealed 97% to 99% cell viability; the opposite effect was observed in DMSO-treated cells (12% viability), having highly significant differences (p < 0.0001) when comparing the concentrations evaluated here ( Fig. 7 ).

A highly significant overlap was found (Fisher’s Exact Test p < 0.0001), with 61 transcripts shared between the two sets.

The ANOVA revealed that the main effects of both the GS model and the growing season were highly significant for all traits ( p < 0.0001).

Activity Against Enterococci Directly after adding 50μg/ml IL-26 to Enterococcus faecalis ATCC 29212 cultures, an immediate and highly significant ( p ≤0.0001) reduction of the number of colony forming units (CFU) of approximately 98.4% was detected.

In particular, a highly significant ORR was seen in patients who developed skin disorders ( P = 0.0001), vitiligo ( P = 0.0004) and thyroid dysfunctions ( P = 0.0127) ( Supplementary Table S4 ).

These differences were highly significant (p < 0.0001).

The mean and median levels of uPA as determined by both ELISAs were similar. However, the mean and median PAI-1 levels assessed by the two ELISAs differed by a factor of 10, the in-house ELISA measuring values ten times lower than the ELISA with commercial reagents. The overall association between the two ELISA methods is demonstrated by the highly significant correlations between the cytosolic levels of uPA (rs = 0.85, P < 0.0001) and of PAI-1 (rs = 0.90, P < 0.0001) (Figure 1A and B).

The following P values were used in the study for the significance: *, P < 0.05 was considered significant; **, P < 0.001 was considered highly significant; and ***, P < 0.0001 was considered very highly significant.

Two-way MANOVA on vector components ( Table 2 ) showed a highly significant effect of angle on combined magnitude and direction (Pillai = 1.202, p < 0.0001), while device type was not significant ( p = 0.569).

Starting the study with MSCs separated from the adipose tissue of the patients with non-healing wounds for autological transplantation, our attention was drawn by a highly significant negative correlation ( p < 0.0001) between the wound size and wound closure degree and by the high percentage (on average 75%) of CD34 + cells among the isolated cells [ 33 ].

Most of all there was a highly significant (p < 0.0001) decrease of LVEF (Figure 2 ), systolic anterior velocity (Figure 3 and 4 ) as well as an increase of LVEDD. 2-D-strain decreased particularly in the anteroseptal, anterior and lateral areas but not at all in the inferior segment (Figure 5 and 6 ).

The difference between the wild-type AV-T and AV-T Δ 1132 is highly significant at p < 0.0001 as determined by a Student’s two-tailed t test.

A highly significant positive correlation was observed between IL-15 and IL-22 (r = 0.606, p ≤ 0.0001).

In contrast, the average tumor volume in MI-503 group was only 587.19 ± 240.69 mm 3 , highly significant smaller than that in vehicle group ( p < 0.0001) (Fig. 4 A).

Using TCGA datasets, specifically, Bladder Urothelial Carcinoma (BLCA), Breast Invasive Carcinoma (BRCA), Colorectal Adenocarcinoma (COAD), and Lung Adenocarcinoma (LUAD), a highly significant positive correlation ( P ≤ 0.0001 in 17 cases, P ≤ 0.001 in two cases, P = 0.01 in one case) was found between A3C, A3D, A3F, A3G, A3H and the mean score of the six hypoxia-induced p53-dependent genes in all these cancers (Figure 1J ).

The Kaplan–Meier survival analysis showed a highly significant difference in OS was detected between the high- and low-risk groups (Log-rank test P < 0.0001), suggesting that the expression of these 5 genes can be effectively distinguished the high- and low-risk of these PC patients (Fig. 4 B and Fig. 5 ).

Following data reduction using PCA there was a highly significant difference in the PERMANOVA ( P =0.0001) in the post-test analysis between the following groups of cats: healthy and FORL-1 ( P <0.0001), FORL-1 and FORL-2 ( P <0.0001).

The latter was highly significant compared to the values of the WT littermates (mixed effects analysis, genotype p < 0.0001, age p < 0.0001, interaction p < 0.0001; Sidak’s post-hoc test 12 m, p = 0.0001).

This was supported by the highly significant Cochrane Q -test ( Q = 1133.19, p < 0.0001) and high heterogeneity indices (I 2 =93.73 %, T 2 =132.95, T = 11.53).

Hence, when looking specifically at peritumoral tumor cell clusters as a surrogate of glial migration and infiltration, the average results between control condition (8 animals) and all chemokine groups were highly significant: CXCL10 (7 animals): 37 vs. 7 ( p < 0.0001), CCL2 (9 animals): 37 vs. 28 ( p = 0.0258), CCL11 (8 animals): 37 vs. 25 ( p = 0.0003) and the combination (7 animals): 37 vs. 24 ( p = 0.0070) ( Figure 3 D). 2.2.2.

The observed difference in mortality between females and males was highly significant (22.2% vs. 8.2%, p=0.0001) (Table 2 ).

The HIV DNA over time GAMM was nonlinear, well representative of the data and highly significant (adjusted R 2 0.84, P < .0001; Figure 2 ).

Consistent with an active increase in firing rate with running speed, regression analysis showed a highly significant positive relationship between running speed/firing rate and running speed/spikes per cycle (slope: 0.92 ± 0.01, R 2 = 0.93, p < 0.0001 k ; Fig. 2 c ).

The statistical model for the soleus peak-to-peak amplitudes of the EMG responses to transcutaneous spinal cord stimulation revealed a highly significant fixed effect of spine alignment condition on the response size (F 2;98 = 47.879, p < 0.0001, ŋ p 2 = 0.494; Figure 3 B).

The pattern of [9 0 0] is highly significant ( p < 0.0001).