“highly significant”

The results show a highly significant CONNECTIVE × EADV interaction (LRT = 56.92, p < 0.0001), see Table 6 and Figure 3 .

More importantly, one-way ANOVA testing revealed a highly significant effect of flow rate on steady-state current ( F = 412.6, p < 0.0001), indicating that the current amplification observed between 0.1 and 10 μL min −1 is statistically robust.

As shown in Fig 4 , the IC 50s for serum inhibition of RBD-ACE2r binding showed highly significant (p < 0.0001) correlation (r s = 0.83) with corresponding IC 50 values from titrated PRNT studies.

Results: We found a highly significant reduction of circulating pDCs ( p < 0.0001) and in bone marrow ( p < 0.0001) of MM patients compared to HD.

coli ATCC 25922; the bacterial LOD was 10 2 –10 3 CFU/mL, with highly significant signal differences ( p < 0.0001).

Although highly significant (chi-square test, p<0.0001), the rather low fraction may indicate competition between CLK:BMAL1 and NPAS2:BMAL1 for binding sites.

Tukey’s multiple comparison test showed highly significant differences between the control and remission groups ( p < 0.0001), the control and active phase groups ( p < 0.0001), as well as between the remission and active phase groups ( p < 0.0001).

The 1–100 band is shown: in a two way ANOVA, merging 20 one-second epochs, with group as between factor and pre-post wave as within factor, a highly significant pre-post wave difference was found F(1,15) = 42, p<0.0001).

sylvestris was highly significant ( p < 0.0001: ****).

The gene expression analysis showed highly significant up-regulation in FLT3 of all AML samples [FLT3-wildtype (0.316 ± 0.05 folds) and FLT3-mutants (0.368 ± 0.03 folds)] in contrast of control group (P = 0.0001).

Although we did multiple comparisons, due to our large study cohort, most of our results were highly significant ( p -value < 0.0001), and would remain significant after correction for multiple comparisons.

The inter annual total case count difference was highly significant (F 11,132 : 36.305, p < 0001).

sPCA analysis revealed highly significant global (p = 0.0001) but non-significant (p = 0.4327) local spatial structures (Supplementary Fig. 2 ), indicating strong signatures of between population separations.

We used the adonis2 function in the qiime2 plugin (q2-diversity) to perform permutational multivariate analysis of variance (PERMANOVA) with 999 permutations, and the included interaction terms (see Table S3 in the supplemental material) and separation of the groups were highly significant ( P = 0.0001).

A highly significant difference ( P < 0.0001) was found.

The results show that the overall model is highly significant ( F = 50.82, P < 0.0001), which means that the factors considered in the model are important for the adsorption process.

The statistical difference in number of accessory genes between MRSP and MSSP isolates as measured using Welch’s t -test was highly significant ( p < 0.0001), with MRSP isolates harboring an average of more than 150 accessory genes compared to their MSSP counterparts ( Figure 3C ).

In contrast, Nrf2 knockdown revealed a suppressive effect on cell proliferation, compared with NTC and Keap1 RNAi, respectively, which became highly significant at 48 h ( p < 0.0001, Figure 4 b).

This model was highly significant (p<10 −4 ) and explained 7.5% of the variation in African ancestry levels between individuals (adjusted R 2 ).

For discrimination of patients with metastasized NEN from presumably cured NEN patients, the combination of cfDNA concentration, hypomethylation, and cfDNA integrity revealed a highly significant AUC of 0.908 (95% CI, 0.83 to 0.99; p = 0.0001) with a positive predictive value (PPV) of 91.1% and negative predictive value (NPV) of 66.7% at the chosen classification cutoff of 0.5 ( Figure 4 B).

At 24 h, the difference in CFU between the combined treatment group and all other groups was highly significant ( p < 0.0001).

On multivariate analysis, CRP remained highly significant for CSS ( χ 2 =17.3, P <0.0001) and OS ( χ 2 =9.8, P <0.002), in addition to other pre-operative variables including log of neutrophil/lymphocyte ratio, red blood cell count and white cell count.

The number of SWATH windows was the most critical parameter with a highly significant (p < 0.0001) impact on the number of proteins quantified.

It revealed a statistically highly significant difference between the average P-IPR and I-IPR per tooth for the lower (0.14 ± 0.19 mm, p < 0.0001) and upper (0.13 ± 0.17 mm, p < 0.0001) teeth.

There were highly significant differences ( P < 0.0001) among all groups regarding almost all postoperative ocular aberration components.