“highly significant”

Results The logistic regression model used to predict the lifetime diagnosis of hypocalcaemia in adults with 22q11·2DS was highly significant (likelihood ratio test: χ 2 = 38·2, df = 7, P < 0·0001).

Among the 48 genes that were both DE and DC, there was a highly significant and positive association in the direction of DE and differential genomic coverage (FET P < 0.0001) with only four genes having higher X SR coverage but higher X ST expression.

On intergroup comparison, there was no statistically significant difference between the groups in the reduction in burning sensation ( P = 0.18) and erythematous area ( P = 0.07), but there was a statistically highly significant improvement in reduction of clinical scoring ( P < 0.01%).

These values were greater than zero for both ACT (Mean = 77.18 μV; t (17) = 6.88, p<10 −7 ) and PASS (Mean = 32.04 μV; t (17) = 3.25, p<0.002), and the difference between ACT and PASS was highly significant (t (17) = 5.5, p<10 −4 ).

Pathologic complete response was a highly significant predictor of DFS and OS in all treatment groups (HR = 0.45, P < 0.0001, and HR = 0.33, P < 0.0001, respectively).

More than 60% of the genes identified as differentially expressed in the first experiment were replicated in the second set of arrays, and we found a highly significant concordance in fold-change estimates for gene expression variation between the two experiments ( ρ = 0.81; P < 0.0001).

The highly significant adhesive effect F 3,24 = 31.37 , p < 0.0001 demonstrates substantial differences among adhesive means beyond random variation.

As expected, highly significant differences were observed between patients and controls in global cognitive status based on the PD-CRS [t(65) = 6.5; p < 0.0001], motor symptom severity based on the UHDRS-TMS [t(65) = 10.9; p < 0.0001], functional status based on the TFC [t(65) = 7.2; p < 0.0001], as well as on NfL plasma levels [t(65) = 10.73; p < 0.0001], all with large effect sizes (d > 0.8). 3.1 Verbal episodic memory performance The three-way mixed-effects ANOVA with recall type (free vs. cued) and time (immediate vs. delayed) as within-subjects factors, and group (HD vs.

Results Quantity of DNA The test of the extraction protocols indicated that in the case of Qiagen Kit, on average, 8.15 ng (SE = 0.39, i.e., 815 ng/g of mandible) of DNA was obtained per sample, whereas the Promega protocol provided on average 19.20 ng (SE = 0.455, i.e., 1,920 ng/g of mandible) of DNA, and the difference was highly significant ( t test, t = 18.35, df = 17.65, p < 0.0001; Table 1 ).

These differences were highly significant ( P < 0.0001, Fisher’s Exact test).

As shown in Figure 3 , rEg.P29 alone did not induce a significant increase in specific IgG at 20 weeks post-immunization, whereas the formulation with Quil A adjuvant elicited a highly significant increase in rEg.P29-specific IgG ( P < 0.0001), confirming that Quil A is essential for inducing a robust IgG-dominant humoral immune response in sheep.

Quantitative analysis revealed a markedly higher clean area/total area ratio in the CADISS group, with statistical testing via the Mann–Whitney U test confirming this difference to be highly significant ( p < 0.0001).

The correlation between model predicted and empirical results was highly significant (P<0.0001), with an R 2 of 0.53 ( Figure 4B ).

Analysis of variance exhibited that effect of T2 (50 mM of KNO 3 ), T4 (150 mM of KNO 3 ) were highly significant ( P < 0.0001, and P < 0.001 respectively) on final seed germination (%) among all priming treatments.

A significant increase of several amino acids including phenylalanine (Phe, p < 0.01), tryptophan (Trp, p < 0.001), and tyrosine (Tyr, p < 0.0001), as well as isoleucine (Ile, p < 0.05), glutamate (Glu, p < 0.05), glutamine (Gln, p < 0.05), and glycine (Gly, p < 0.05) was observed, whereas a highly significant ( p < 0.0001) decrease in cysteine (Cys) was measured.

Cumulative food intake progressively increased in TA3-treated animals compared with controls, with significant differences emerging from day 8 onward and becoming highly significant by day 14 ( P < 0.0001) ( Fig. 1E ).

5d ) were highly predictive of dhurrin concentration owing to a marginally significant additive (linear model coefficient estimate t = –2.18, P = 0.03) and highly significant quadratic ( t = 4.97, P < 0.0001) effect on untransformed dhurrin levels.

Significance levels were categorized as follows: p > 0.05 (ns) for non-significant, p ≤ 0.05 (*) for statistical significance, p ≤ 0.01 (**) for very significant, p ≤ 0.001 (***) for highly significant, and p ≤ 0.0001 (****) for extremely significant, respectively.

As shown in Table 2 , the first canonical function (F1) had the highest eigenvalues and was highly significant across all fertility scales (Bartlett’s test, p < 0.0001), concentrating most discriminatory information.

All intergroup differences were highly significant ( P = 0.0001; pairwise comparisons P < 0.001).

In the 41 individuals identified as hatchery descendants ( Table 5 ), this frequency (*90 allele) was very much smaller ( q = 0.036), being the difference between this and the frequency of the whole pool of hatchery samples highly significant (Chi-Square of 37.95, 1 d.f., p < 0.0001).

In the Kruskal–Wallis analysis, the Ma QTL was supported with a highly significant (P < 0.0001) value of the K statistic, 15.9 for malic acid content.

The inverse relationship between the axons’ regeneration probabilities and the sizes of their cell bodies was highly significant (r = 0.92, p < 0.0001; Figure 1 C). 3.2.

Testing for CYP2C19 was more frequently requested in men (63%) than in women (37%) ( p = 0.0007), while CYP2D6 showed a highly significant predominance in women (94% vs. 6%, p < 0.0001, Fisher’s Exact test).

The log-rank test for the overall difference among the four survival curves was highly significant ( P < 0.0001), providing strong evidence against the null hypothesis of no difference in survival distributions between the CTI groups.