“highly significant”

The correlation between duration of illness and grey matter volume across all networks (uncorrected for TIV and age) showed a highly significant correlation (r = −0.37, p < 0.00005) which was no longer significant after correcting for age and TIV (r = 0.06, p = 0.56).

In contrast, when used in the study of 120 colorectal cancers, these four markers detected a LOH in 38 out of 85 informative cases (45%), a difference that is highly significant (X = 16.38; P<0.00005).

The results presented in Table 3 showed a highly significant ( p value = 0.00005, detection limit of the method being approximately 1 log CFU, CI-95%, 1.85, 2.77) log reduction (2.31) in microbial load after wiping the meat surface with the developed DW (count before treatment—5.48 log CFU/cm 2 ; after treatment—3.17 CFU/cm 2 ).

There was such increases of 4.4 dB for each of the groups Education , Other and Music , and they were highly significant (p<0.00005, Tukey's HSD).

When exposing 104C1 cells that acquire a fibroblast morphology to increasing concentrations of KDC203, we observed highly significant ( p <0.00005) dose-dependent reductions in PrP C levels ( Fig 2A ).

Functional enrichment of the 606 putative hypoxia genes revealed highly significant functional groups ( p < .00005) related to oxygen sensing and hypoxia (GO:0036293, GO:0070482, GO:0001666, GO:1901700) and energy management (GO:0015979, GO:0019684, GO:0009765, GO:0009055, and GO:0004022).

The difference between the survival curves for of the high and low risk phenotypes is highly significant (p < 0.00005).

To gain further insights into their upstream kinases, we conducted a motif enrichment analysis, revealing a prevalent sequence motif surrounding the phosphosites with a highly significant proportion of arginine at position −3 (odds ratio = 4, p = 5e−05) ( Figure 2 G).

The trained birds' preference for the Dreadnought Grey disc was statistically highly significant (P<0.00005, using the binomial statistics described in “ Methods ”).

SChLAP1 expression was highly significant when distinguishing CP and PCSM (p = 0.00005 and p = 0.002, respectively) ( Fig. 2d,e ).

However, Filtek sealed in water shows a highly significant increase in roughness as early as 1 day ( p ≈ 5 × 10 −5 ) that continues at 7, 14 and 90 days.

BALB/c mice vaccinated with 20 μg of SLA plus 50 μg of CpG ODN showed a highly significant (P<5×10 −5 ) reduction in swelling compared to SLA-vaccinated mice and enhanced survival compared to unvaccinated mice.

In contrast, the noncancer group exhibited lower methylation rates, showing a highly significant statistical difference ( p < 0.00005, Figure 2 A, EXdata 2.

The difference between male and female patients was highly significant ( P = 0.00005, χ 2 test).

The difference in the distributions of the number of viable daughter cells per mother cell is statistically highly significant with a p -value < 0.00005 (two-sample t -test).

The statistical data analysis showed that the length of inpatient treatment affects the outcome of the treatment and that the difference is statistically highly significant (p < 0.00005).

Differences were highly significant at 3 hours among all groups ( P <0.00005).

The majority (90.2%) of children with autism spectrum disorder without intellectual disability were born from 1994 to 1999 ( Table 1 ) and compared to the number born in 2000 to 2005, the difference is highly significant ( P < .00005).

We found that the pair of chromosomes 4 and 5 show highly significant nonindependence across the set of crosses (Bonferroni adj., p = 5 × 10 −5 , permutation test, Figure 5B ), suggesting a genetic interaction between this specific pair of chromosomes.

In addition, to mitigate potential impacts of small expected counts (e.g., expected values < 5 for TPS-c) on the chi-square approximation, a permutation test (20,000 permutations) was performed and also yielded a highly significant result ( p ≈ 5.0 × 10 −5 ), further supporting that the distribution of core/non-core status varies significantly among subfamilies.

This revealed a highly significant correlation (r = 0.80, p<0.00005; Appendix 2—figure 1D ).

To further avoid approximation error, we additionally conducted a permutation test (randomly shuffling the Core/Dispensable labels 20,000 times and recalculating χ2), which remained highly significant ( p ≈ 5.0 × 10−5) (Fig. 4 C, Table S14), supporting that “the distribution of core/dispensable genes changes significantly across subfamilies”.

Treatment with clopidogrel was found to confer a risk reduction of 20% on the composite endpoint, at a highly significant P = 0.00005.

We then plotted the observed responses to random textures against the predicted responses, the resulting correlation was positive and highly significant ( r = 0.75, P < 0.00005; Fig. 6 B ).

Only five genomic loci yielded highly significant scores ( p < 0.00005), and these loci emerged in all experimental conditions and replicates, showing no evidence of differential expression (see Supplemental Figure 6 ).