“highly significant”

There was a highly significant effect of regions (linear mixed model, P = 0.000049).

Myc knock-down had a highly significant effect on the extent of glial dedifferention (one-way ANOVA, F (3,13)=18.99, p =4.94×10 −5 ).

The trained birds' preference for the Dreadnought Grey disc was statistically highly significant (P<0.00005, using the binomial statistics described in “ Methods ”).

To exclude the possibility that an individual SNP behaved aberrantly in the analysis, we also sequenced the SNP 6651T > A, yielding similar findings, and both SNP assays combined, the observation of allelic imbalance in cases versus controls was highly significant ( p < 0.00005 by t test).

In contrast, the noncancer group exhibited lower methylation rates, showing a highly significant statistical difference ( p < 0.00005, Figure 2 A, EXdata 2.

The difference between the performance of two group in OSPE was highly significant ( P < 0.00005).

The correlation between duration of illness and grey matter volume across all networks (uncorrected for TIV and age) showed a highly significant correlation (r = −0.37, p < 0.00005) which was no longer significant after correcting for age and TIV (r = 0.06, p = 0.56).

The majority (90.2%) of children with autism spectrum disorder without intellectual disability were born from 1994 to 1999 ( Table 1 ) and compared to the number born in 2000 to 2005, the difference is highly significant ( P < .00005).

This revealed a highly significant correlation (r = 0.80, p<0.00005; Appendix 2—figure 1D ).

Treatment with clopidogrel was found to confer a risk reduction of 20% on the composite endpoint, at a highly significant P = 0.00005.

A comparison of those relations is presented in Table 3 . In single-factor analysis of variance (ANOVA) of polyp diameter in subgroups created with reference to PTEN protein expression, only highly significant differences ( p = 0.00005) were observed.

We then plotted the observed responses to random textures against the predicted responses, the resulting correlation was positive and highly significant ( r = 0.75, P < 0.00005; Fig. 6 B ).

Using a highly significant P value cutoff ( P < 0.00005), we identified 12 proteins that exhibit differential expression between these OA subsets (Figure 3 ).

We identified highly significant correlation differences between incident CAD cases and controls ( p < 5 × 10 –5 ); eGFR correlated more strongly with 3-hydroxyisobutyrate ( r case-to-control = 0.29), citrate ( r case-to-control = 0.42), and glycine ( r case-to-control = 0.35), while 4-deoxyerythronic acid correlated less strongly with triglycerides ( r case-to-control = −0.35), and hypoxanthine with creatinine ( r case-to-control = −0.30) in individuals with incident CAD.

While in our DESeq analysis, this transcript fell just below the cutoff for fold change (1.24) the p -value was highly significant ( p -value = 5 × 10 −5 ), consistent with our qPCR results ( p -value = 0.0011, Holm-Sidak corrected).

This perfect association between hot-spot S2 activity and the presence of S9.1G is highly significant ( P = 0.00005, or 0.0012 after Bonferroni correction for additional markers tested across this region).

Differences were highly significant at 3 hours among all groups ( P <0.00005).

To gain further insights into their upstream kinases, we conducted a motif enrichment analysis, revealing a prevalent sequence motif surrounding the phosphosites with a highly significant proportion of arginine at position −3 (odds ratio = 4, p = 5e−05) ( Figure 2 G).

BALB/c mice vaccinated with 20 μg of SLA plus 50 μg of CpG ODN showed a highly significant (P<5×10 −5 ) reduction in swelling compared to SLA-vaccinated mice and enhanced survival compared to unvaccinated mice.

In both years, the differences among accessions were highly significant ( p = 0.00005 and p = 0.00003, respectively).

Moreover, we compute the Pearson correlation coefficient (r) and mean absolute error (MAE) for cellularity estimations, and the results show that the estimated cellularity of CLImAT-HET has a highly significant positive correlation (r > 0.99, p -value < 5 × 10 −5 , MAE < = 0.02) with the underlying cellularity across all simulated samples (Fig. 3a , b and c ), which demonstrates CLImAT-HET’s ability to precisely recover clonal architecture.

SChLAP1 expression was highly significant when distinguishing CP and PCSM (p = 0.00005 and p = 0.002, respectively) ( Fig. 2d,e ).

Functional enrichment of the 606 putative hypoxia genes revealed highly significant functional groups ( p < .00005) related to oxygen sensing and hypoxia (GO:0036293, GO:0070482, GO:0001666, GO:1901700) and energy management (GO:0015979, GO:0019684, GO:0009765, GO:0009055, and GO:0004022).

However, Filtek sealed in water shows a highly significant increase in roughness as early as 1 day ( p ≈ 5 × 10 −5 ) that continues at 7, 14 and 90 days.

We found that the pair of chromosomes 4 and 5 show highly significant nonindependence across the set of crosses (Bonferroni adj., p = 5 × 10 −5 , permutation test, Figure 5B ), suggesting a genetic interaction between this specific pair of chromosomes.