“highly significant”

Scores from PCA were normally distributed ( p > 0.2), and the DFA among the 19 locations was highly significant (Wilks’ Lambda: 0.44442, F (33,922) = 8.8617, p < 0.00001, n = 533).

The positive relationship between φ and geographical distance was statistically highly significant (Mantel test, 100000 randomisations, r = 0.375, P = 0.00001), also when corrected for beetle phenotype (Partial Mantel test, 100000 randomisations, r = 0.379, P = 0.00001; see Materials and Methods for comments regarding the value of r of the Mantel test).

Finally, we tested our key predictive variable (ACE count with and without AAA support) against five different individual or combined dependent variables (Table 2 ) with, in each case, the overall contribution of the variable being highly significant at P <0.00001.

[ 32 ] led to highly significant heterogeneity ( p < 10 −5 and I 2 = 94 %); consequently we excluded this study from the meta-analysis.

We chose a highly significant setting ( L = 10 kb, N = 3, and h n ≥ 2; P < 10 −5 ) that both allowed for extending clusters over genes potentially missing from the expression array and assured that a cluster was not solely formed by a single set of duplicated genes (since h n > 1) (Figure 1A and B ).

Our meta-analysis found a highly significant difference between the two groups (MD = −0.95, 95% CI, [−1.27–0.64], P < 0.00001, Fig. 6 ).

4 B) have sampling distributions that overlap for H3N2 and H1N1 (all years), while the same distributions for prepandemic H1N1 do not, hereby showing that the shift in H1N1 connectivity network is highly significant (with 10 5 replicates: P < 10 −5 ).

Within-group comparisons of SI increases from T1 against T2 values yielded highly significant differences for CPP–PCs ( n = 57, 0.23 ± 0.05 bits per spike, mean ± s.e.m.; P = 1 × 10 −5 , T = 4.86, one-sample t -test) and SAL–PCs ( n = 61, 0.26 ± 0.07 bits per spike, mean ± s.e.m.; P = 4.5 × 10 −4 , T = 3.7, one-sample t -test).

Figure 7 a shows the relationship between LAI r and LAI-vc e by applying method (ii) with k r obtained by inverting Equation (7), which rendered highly significant statistical analysis ( Table 4 ) as expected ( R 2 = 0.94; b = 0.98; SEE = 0.71; RMSE = 0.15; p < 0.00001).

The highly significant difference in values ranged between 57 pg/mL ( P < 0.00001), 161 pg/mL ( P < 0.00001), 112 pg/mL ( P < 0.00001), 67 pg/mL ( P < 0.000008), and 226 pg/mL ( P < 0.000005), respectively for IL-1 α , IL-1 β , IL-6, MCP-1, and TNF- α .

Some of the very highly significant hits ( P < 0.00001; Table 1 ) were, however, not found at high levels on fibroblasts.

We found highly significant overlaps (p<10 -5 ) for three of the factors (Egr2, Irf8, and Sp4) that exist in both datasets, and a border-line significant overlap for the fourth (Smarca4), validating the quality of the edges in our network.

All the variables included in the model were highly significant at a p<0.00001 ( Table 2 ).

The highly significant P-value (P < 0.00001) in our study suggests a non-random occurrence, further emphasizing the condition’s strong presence in the population under investigation.

T-test statistically confirmed the highly significant response of M2e ELISA test to live virus infection at p = 0.00001(data not shown).

The discriminant validity was demonstrated by highly significant differences ( p < 0.00001) between the treatment groups across multiple timepoints, with a strong effect size at three months.

Besides, we use the Pearson Chi-Square test to evaluate the distribution of FIGO stages I, II, III, IV among expansile and infiltrative tumors, and found there was a highly significant association between tumor type and FIGO staging (Pearson chi2(3) = 110.9206, p <0.00001) Figure 4D . 3.3.4 Publication bias Publication bias was investigated by Begg’s funnel plots.

Effects of reproductive status and diagnosis on polysomnographic measures (with age as a covariate) The omnibus MANOVA (without covariate) was highly significant for RS ( P <.00001) but was non-significant for diagnosis ( P =.364) and the RS x diagnosis interaction ( P =.811).

The contrast for the 2-back to the 0-back condition for RVE (Figure 4 ) shows widespread and highly significant ( p < 10 −5 ) increases in entropy throughout the brain.

Testing for heterogeneity showed a highly significant result (p<0.00001) and high inconsistency (I 2 = 94%).

Mean linearized ITs of the ALDVICO to all pathogen races of the same species were positively correlated with one another and highly significant (P< 0.00001) ( Supplementary Figure S4 ).

The conversion rate was 2.53% ( n = 133/5263) in the robotic and 11.94% ( n = 3874/32,442) in the laparoscopic group, and was highly significant to the favor of the robotic group ( p < 0.00001). 4.

Genetic structure was highly structured among these groups of populations (AMOVA; permutation tests highly significant, P <0.00001), meaning that most of the genetic variability was partitioned among groups (77.28%), and only a small proportion of the variability was partitioned among populations within groups (14.71%) or within populations (8.003%).

Highly significant correlation was observed between HRD score and HR deficiency for both cohorts ( P =10 −5 and P =10 −29 , respectively) with HRD score being distinctly reduced among ovarian tumours with intact BRCA1 and BRCA2 ( Figures 2B and C ).

Neurophysiologic Analysis Not surprisingly, in keeping with prior studies (e.g., 28 , 55 , 57 ), on average, there was a highly significant effect of odorant on both the spatial patterns of different odorants (F [4, 430] = 128.28; P < 0.00001) and the response magnitude (F [4, 437] = 117.26; P < 0.00001).