The difference was highly significant (X 2 = 942.69, p < 0.00001).
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The patient is assigned the high or low risk of relapse category if the score is ⩾2.41 or <2.41, respectively, with highly significant differences in RFS ( P <10 −5 ) and OS ( P <10 −5 ) between both groups.
Relative to the codon frequency of the native DNA, the Mann-Whitney-Wilcox rank-sum analysis of the optimized CDSs shows that two are non-significantly (n.s.) optimized, four exhibit a p value between 1.4E−03 and 7.7E−04, and three are highly significant with a p < 1E−05 (GenScript, GeneArt, COOL).
In fact, both correlations are highly significant (p < 0.00001 for each in Fig 2B ).
A Monte Carlo simulation determined that this is a highly significant overlap (p<1 × 10 −5 ) and peak heights at shared ATAC and CATaDa peaks show significant correlation (p<1 × 10- 16 , r 2 = 0.138) ( Figure 2—figure supplement 2A ).
The dF/S analysis revealed a highly significant enhancement of syx-GFP cluster formation of over 60% by vSyx (p < 0.00001, Fig. 2D ).
Cytokine-derived principal components: cytokine profiles The highly significant Bartlett’s test indicated that the cytokine data were suitable for PCA (χ 2 = 856.6, P < 0.00001).
When combining men and women, the difference was highly significant (9.4% versus 7.81 %) when comparing the dementia group to the control group ( p < 0.00001) ( Table 3 ).
Group differences were highly significant at the overall p = 0.00001 level.
Based on the two tailed Mann‐Whitney U test, the estimated P values for comparing these aiLUNG‐COVID‐19 vs aiLUNG factors were highly significant at P = .00001.
The diverging instrumental effects of DBP and SBP on migraine were also supported by restricting analysis to SNP instruments that were non-significant ( P > 0.05) for one measure but highly significant ( P < 1 × 10 −5 ) for the other (Supplementary Fig. 28 ).
The analysis revealed strong, highly significant LD (p < 0.00001) between HLA-A and the Class I loci HLA-C and the Class II loci HLA-DRB-1.
In exploring the subgroup for tensile strength ( Table 4 ) there was a highly significant difference ( P < 0.00001) when nano filler was added to the material, however there was no significant difference when micro fillers were added ( P = 0.74). 3.1.2.
This is also exhibited by mostly negative differences between the single-cell volumes 60 and 2 min after their exposure to sucrose-water solutions ( Figure 5C ), which lead to highly significant differences ( p < 10 –5 ) when compared with the results of the corresponding Leibovitz-water solutions.
This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.
The association was highly significant, with p < 10 5 up to 528 nm (i.e., rings r 1 –r 4 ) relative to randomly distributed particles.
Total physical activity (TPA) The meta-analysis of eight studies showed that mHealth interventions produced a moderate and highly significant improvement in TPA among pregnant women (SMD = 0.44, 95% CI: 0.31 to 0.57, P < 0.00001), with very low heterogeneity (I2 = 0%), indicating good consistency and robustness of the results (Fig. 4 ).
4 a, b; Tables 2 and 3 ), and the effect of temperature is highly significant (larvae: F 1, 570 = 3727.9, p < 0.00001; pupae: F 1, 570 = 3311.6, p < 0.00001).
In both cases, the calibration curves showed a highly significant linear response over a concentration range spanning two orders of magnitude ( R 2 > 0.99; p value < 10 −5 ; Fig. 3b, c ).
And finally, when comparing JN and A-VMN directly using the blow-by method of delivery, a 6-fold increase in the mass of drug was found ( Table 2 ) ( p = 0.01567), with a highly significant lower residual volume in the A-VMN also observed ( p = 0.00001).
A relatively small number of the correlations were strong ( R > 0.4) and highly significant ( p < 1e−5 and FDR < 0.016) (Fig. 4 a).
borderline significanceP = 0.017
In a meta‐analysis of six studies of CRT, the 95% CIs for the improvement in peak VO 2 with CRT went from 0.32 to 3.22 mL/kg/min, with borderline significance, P = 0.017, 35 compared with the narrower CI, and more highly significant effect seen here: 95% CIs for the improvement in peak VO 2 with CCM between 0.56 and 1.30 mL/kg/min, P < 0.00001, giving a considerably more precise estimate of efficacy and of increased statistical significance.
The combined group demonstrated a substantially larger and highly significant positive effect (SMD = 2.02, 95% CI: 1.83 to 2.21; P < 0.00001).
There was a go highly significant ( p = 0.00001) prevalence of Nab against NFL, IgM and IgG, as well as NFH and GFAP, IgG in MCI patients.
In the SA27063 × A17 F 2 population a highly significant quantitative trait locus (QTL, LOD = 7.37; P < 0.00001) named r esistance to the n ecrotroph P homa m edicaginis one ( rnpm1 ) genetically mapped to the top arm of linkage group 4 (LG4). rnpm1 explained 33.6% of the phenotypic variance in the population's response to infection depicted on a 1–5 scale and was tightly linked to marker AW256637 .