“highly significant”

Interestingly, expression was limited to grade 2 and 3 DCIS with a highly significant interaction (p < 0.00001) between PPARγ and grade.

The overall effect was highly significant (Z = 12.27, p < 0.00001), supporting the robust efficacy of the treatment in reducing the uterine size ( Figure 5 ).

All primary outcomes showed significant improvement post treatment at BF-corrected alpha of p < .0028: There was a highly significant post-treatment drop of general psychiatric symptoms (SA-45 global severity index; p < .00001, d = 1.08).

These differences were highly significant (P < 0.00001).

Despite this heterogeneity, the overall effect size is highly significant ( Z = 30.91, p < .00001).

The χ 2 results show that likelihood ratio statistics are highly significant ( P < 00001) suggesting that the model has a strong explanatory power.

The main effect of the post-error was highly significant ( F (1,37) = 204.6; p < 0.00001) indicating that response time increased after errors in a stop trial (Fig. 3a : the difference between the after-error and after-correct trials).

The main factor Language was highly significant, F (1, 33) = 98.69, p < 0.00001, reflecting the overall better performance of Tashlhiyt than French participants.

Inter-rater reliability was highly significant (Cohen's κ = 0.62; Z = 19.1; P << 0.00001; number of errors = 90).

Pre-saturation of EGFR on A431 cells with an excess of both non-labeled ZEGFR:2377 and cetuximab caused a highly significant (P<1×10 −5 ) reduction of 89 Zr-DFO-Z EGFR:2377 binding to the cells.

However, the highly significant differences in sputum conversion ( P <0.00001) corresponded to only slight differences in the conversion rates (86.6% vs. 84.3%).

Effect of SR on HR Figure 2 shows that the effect of SR is highly significant, although clinically small: 1.65 bpm [95%CI: 1.19, 2.11], p < 0.00001, random effect, or 1.40 bpm [95% CI: 1.05, 1.75], fixed effect.

Figure 7 a shows the relationship between LAI r and LAI-vc e by applying method (ii) with k r obtained by inverting Equation (7), which rendered highly significant statistical analysis ( Table 4 ) as expected ( R 2 = 0.94; b = 0.98; SEE = 0.71; RMSE = 0.15; p < 0.00001).

Single-marker FBAT analyses display only a non-significant trend in this direction, possibly due to small sample size, but confirm a highly significant divergence in allelic transmission probabilities between autistic patients and unaffected siblings at this locus (P < 1 × 10 -5 , table 5 ).

Three additional islands of highly significant homology ( P < 10 -5 ) were identified further upstream.

The results were highly significant (R = 0.96, p < 0.00001), indicating that the variations in codon usage are strongly correlated with the nucleotide content (i.e., GC content) of the genes.

The conversion rate was 2.53% ( n = 133/5263) in the robotic and 11.94% ( n = 3874/32,442) in the laparoscopic group, and was highly significant to the favor of the robotic group ( p < 0.00001). 4.

Although Pd-MOF produced a highly significant downregulation of VEGFR2 gene expression in A549 cells compared with the untreated control ( p < 0.00001; Fig. 7 D), its inhibitory potency remained considerably weaker than that of the reference drug, sorafenib.

The mean synonymous site nucleotide diversity ( π syn ) for X-linked genes (Tables 1 and 2 ; Additional file 1 : Table S4) is 0.00017, versus 0.0018 for all autosomal genes identified; the mean estimated nucleotide diversity for all sites ( π ) is 0.00038 for the X-linked region, again much lower than values for the autosomal region or PAR (0.0017 and 0.0020, respectively, which do not differ significantly (Wilcoxon rank sum P = 0.12), while the difference from the X-linked region is highly significant ( P < 1 × 10 −5 ) for both regions).

Overall, supporting the validity of the estimated model parameters, a simple correlation analysis between observed confidence changes and estimated changes computed with the mathematical model equations, yielded a highly significant correlation ( n =20, Pearson's r =0.748, P <10 −5 , Supplementary Fig. 7c ).

This overlap is highly significant ( P -value < 1e-5), especially given that Met4 ChIP-seq only shows 45 peaks throughout the entire genome.

But the actual percentage of double-positive bipartite synapses was much lower, only 4.8 ± 1.8%, and the difference was highly significant (p < 10 -5 , two-tailed t -test).

In fact, highly significant ( P < 10 −5 ), down-regulated DEGs were more abundant than up-regulated ones (blue circles in Figures S3 , S4 , and S11 ).

In the SA27063 × A17 F 2 population a highly significant quantitative trait locus (QTL, LOD = 7.37; P < 0.00001) named r esistance to the n ecrotroph P homa m edicaginis one ( rnpm1 ) genetically mapped to the top arm of linkage group 4 (LG4). rnpm1 explained 33.6% of the phenotypic variance in the population's response to infection depicted on a 1–5 scale and was tightly linked to marker AW256637 .

Results Nadi Shodhana Pranayama showed a significant decrease in ART (p = 0.01) and Bhramari Pranayama showed a highly significant decrease in ART (p < 0.00001).