“highly significant”

The recovery of thigh atrophy was highly significant, with a p -value = 0.00001.

The excess of GCGC counts at position −13 (50 GCGC motifs) relative to any other position in the promoter region was highly significant, with p -value < 0.00001 using a two-tail binomial test.

In particular, the differences are highly significant on branch #1 and branch #2 during the genome reduction period (Student's t-test, P- value<10 −5 ).

Highly significant inter-study heterogeneity was noted (I 2 = 85%; χ2 p= 0.00001).

All pair-wise comparisons showed highly significant levels of population genetic differentiation (P<10 -5 , Table S2 ).

The strength of this dependence between the aCVT and aCrVT is demonstrated by highly significant p-values using a Fisher’s Exact Test of Independence (left p = 0.00001 and right p = 0.00018).

Differences between recordings at 0.3, 0.7, 1.0, 1.3 and 1.7L/s were highly significant as revealed by Friedman test (p<0.00001).

That study uncovered single highly significant effect ( p = 0.00001) showing ADHD adults had increased rightward P8–P7 beta2 asymmetry during the CPT, and in post hoc analysis confirmed that this result was specific to the beta2 frequency band.

But the actual percentage of double-positive bipartite synapses was much lower, only 4.8 ± 1.8%, and the difference was highly significant (p < 10 -5 , two-tailed t -test).

The absence of effect in the non‐treatment groups suggests that there may be a true treatment effect from most exercise regimes. Vergence facility (VF) There was a highly significant change in responses (main effect F 1,145 = 73.8, p < 0.00001) and marginal group/change interaction (F 7,145 = 1.93, p = 0.07).

Results from AMOVA showed that while most of the genetic variance was partitioned within populations (89.8%), a significant proportion of the variance was partitioned among populations (10.2%) and gave a highly significant Φ ST value (0.102, P <0.00001).

Four of the 142 sequenced genotypes were identified as outliers along four different and highly significant axes of variation ( P < 10 −5 from tests based on the Tracy–Widom distribution) based on the default settings of the smartpca program within the EIGENSOFT package ( Patterson et al. , 2006 ).

The difference in classification performance between sexes was highly significant (Mann–Whitney U‐test, p < 0.00001, Figure 4A , effect size d = 0.8), showing a strong sex‐related bias in models trained without using ERP features.

The difference in the concordance of these 2 data sets was highly significant (p<0.00001).

The discriminant validity was demonstrated by highly significant differences ( p < 0.00001) between the treatment groups across multiple timepoints, with a strong effect size at three months.

For all these follow-ups, meta-analyses showed highly significant results for the comparison between resin-based sealants and not treatment ( p < 0.00001) meaning that resin-based sealants efficiently prevented caries in children’s first permanent molars.

Those receiving a RVPA shunt had highly significant differences ( p <0.00001) in remodelling of the RV corresponding to ventricular dilatation (p = 0.001) and increased sphericity ( p = 0.006).

The overall effect was highly significant (Z = 12.27, p < 0.00001), supporting the robust efficacy of the treatment in reducing the uterine size ( Figure 5 ).

Although separation of the samples from the neighboring countries of Brazil and French Guiana was not visually resolved by the first two principal components in PCA (POV = 21), the F ST value was still highly significant (F ST = 0.10, p < 10 -5 ) ( Fig. 5B ).

There was a strong relationship with sleep disturbance as indicated by highly significant correlations with all four SQS subscales (all p < 0.00001) but not with hours of sleep.

To lend further support to the relationship between hepatic inflammation and TG levels in the liver, there were highly significant positive correlations between hepatic TG levels and TNFα (P < 0.00001), MCP1 (P = 0.0001), IL6 (P < 0.001) and IL1β (P < 0.00001) protein levels.

The standard post-operative treatment in most early trials was CMF polychemotherapy (cyclophosphamide, methotrexate, and 5-fluorouracil), but recent evidence suggests that there is a small but highly significant further survival benefit with anthracycline-based regimens (RR=0.89; 2 P <0.00001) ( EBCTCG, 2005 ), and these have become widely accepted as standard adjuvant chemotherapy.

In a European patient cohort study of 110 candidate polymorphisms, Hhex SNP rs1111875, a major risk factor in T2D, was found to be a highly significant risk factor (p<0.00001) for AD, but only with the accompanying GSTM3 (rs7483) SNP ( 171 ).

In contrast, five of the 13 SCC control cases exhibited P63 positivity, demonstrating a highly significant association (p < 0.00001).

A meta-analysis of 2921 participants with type 2 diabetes treated with an IL-1-blocking therapy showed a highly significant reduction in HbA 1c ( p <0.00001 [ 88 ]).