“highly significant”

Similarly, ‘IBD Region’ (left colon, right colon, rectum, sigmoid, transverse, ileum) showed highly significant associations in UC and CD ( p < 0.000001), indicating that anatomical location of involvement may be another important component of the molecular heterogeneity underlying IBD.

One-way ANOVA for repeated measures followed by Tukey post hoc test revealed a highly significant difference ( p < 1 × 10 −6 ) between Fe-treated animals versus the other three groups (Fig. 1 b).

A total of 151 genes were regulated by hypoxia in both datasets (Figure 1D ), and a permutation test revealed such an overlap between the two datasets was highly significant ( P < 1 × 10 −6 ; Supplementary Figure S1B ).

Similarly, rs2242652 showed increased TERT expression in the GA genotype compared with the GG genotype, while the AA genotype—despite the smaller sample size—followed the same trend, with highly significant associations ( p ≈ 10 −6 –10 −5 ). 3.9.

Differences between populations accounted for only 6.96% of the variance, but was highly significant ( P < 1.0 * 10 −6 ).

The prevalence varied between 18.2 and 50.7 %, depending on locality, and this variation proved to be highly significant (χ 2 = 59.599; P < 0.000001) (Table 1 , Fig. 1 ), suggesting a focal occurrence of borreliosis.

All comparisons were highly significant ( p < 0.000001), confirming that the antimicrobial effect of PAW was not transient and was maintained within 24 h storage.

In confirmation of our hypothesis, there was a highly significant, 9.4-fold, increase in the maximal tetanic force (7.5±0.94 g versus 0.8±0.2 g; p=≤0.000001) elicited by ONS in the engrafted OST group of SOD1 G93A mice at late-stage disease, compared to age-matched untrained SOD1 G93A mice (132.4±6.8 days versus 133±6.9 days; n=7 and 11, respectively; Figure 5C–G and Appendix 1—table 3 ), although OST did not alter contractile rate characteristics ( Figure 5—figure supplement 5A–C ).

When all tumor samples were evaluated together the correlation of GZMH, ABL1, IL-7, LY9, IL-12, SCAMP3, and CD244 were highly significant ( p < 1 × 10 −6 ).

ANOVA with the main factor Age-Group (adults, children) and repeated measures factor Velocity (3 conditions) revealed a highly significant effect of Velocity on gamma power (F (2,122) = 172.8, ε = 0.87, p < 1e −6 ; η 2 = 0.74), but no effect for the Age-Group or the Age-Group*Velocity interaction (p’s > 0.6).

As shown in Figure 3 , while reduction in binding after treatment with unlabeled DARPin 9_29 was highly significant ( p < 0.000001), there was neither significant reduction in binding after receptor saturation using trastuzumab ( p > 0.05) nor any reduction in binding after treatment of SKOV-3 cells with cetuximab or bevacizumab.

We observed a highly significant reduction in rolling in response to noxious stimuli compared to both controls when we inactivated the nociceptive class IV neurons (Chi square test, p< 10 −6 , Fig. 4A and 4B and Table S1 ) [2] , [29] , [40] .

7 ) revealed that the increase in accuracy was highly significant (monkey A: χ 2 = 95.3, P < 10 −6 ; monkey G: χ 2 = 60.6, P < 10 −6 , Chi-Square test).

A paired t test revealed a highly significant and strong decrease in the mean slope from the EO to EC condition in the combined group of subjects ( T (82) = 5.81, p < 0.000001, Cohen d = 0.64), as well as in the separate groups (TD: T (44) = 3.67, p = 0.0006, Cohen d = 0.55; ASD >85 : T (22) = 3.38, p = 0.0003, Cohen d = 0.71; ASD <85 : T (14) = 3.31, p = 0.005, Cohen d = 0.85; Fig. 2 D).

Upon initial analysis, the storage process demonstrated a highly significant effect (Hotelling multivariate p-value = 1 × 10 −6 ).

We find subtle, but highly significant (p < 10 −6 ) differences in relative height and relative radius between the two populations ( Fig. 2e, g ).

The association between Harvard step test and overweight was statistically highly significant (p=0.000001) with odds ratio of 24.65 (C.I. = 9.97; 68.68). 4.

However, in the presence of added adenosine (3 or 10 μmol/L), guanosine (10–100 μmol/L) decreased proliferation of both cell types, thus resulting in a highly significant ( P < 0.000001) interaction between guanosine and adenosine on cell proliferation.

The difference between AD and HC was 64.47% with 95% confidence interval from 56.87% to 72.08%, and it was highly significant ( P < 0.000001).

A three-way ANOVA revealed a highly significant behavior × USV × respiratory frequency interaction ( F (32,1344) = 5.44, p < 0.000001) and further two-way ANOVAs showed a significant main effect of USV for both freezing ( F (1,21) = 6.29, p = 0.02) and escape ( F (1,21) = 18.05, p = 0.0004) states.

This effect is small; on average people get about 6% faster and spend about 1% less time buzzing, but highly significant ( p <10 −6 for both metrics, t -test).

the nascent bond show that all of these active site dynamics are highly significant with p < 10 −6 ( Fig.

Global analyses identified a total of 2,053 sites with overlapping peaks, and statistical analyses showed that this overlap is highly significant ( Figure 2 B) (p < 10 −6 , calculated using a permutation test with 1.0 × 10 6 iterations).

This interpretation is further supported by the Pairwise Homoplasy Index (PHI) test implemented in SplitsTree, which returned a highly significant result ( P < 1e-6), suggesting that the observed pattern of site incompatibilities is unlikely to arise under a strictly clonal (non-recombining) model.

showed a highly significant correlation between final VA and the presence of RD (p <10 -6 ) which makes retinal detachment one of the main limiting factors for a favorable visual outcome ( 6 ).