These clusters are robust to changes in network parameters and are highly significant (p-value < 1 x 10 -6 , permutation tests).
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However, for intergroup comparison, the difference between the two modes was found to be highly significant in both sedated and awake states if we considered inspiratory hold in PAV+ as PMI ( P = 0.000001 for both states).
MICs of individual and combined EOs were statistically compared using one-way ANOVA ( n = 3), revealing highly significant differences ( p < 0.000001) for all tested fungal species.
Prior to statistical analysis, SNP data were filtered, using the BITE package 61 in R v4.0.5, according to the following criteria: (i) SNPs with call rates less than 95%, (ii) minor allele frequencies less than 5%, (iii) missing genotypes more than 5%, and iv) SNPs with highly significant deviation from the Hardy–Weinberg equilibrium ( P -value < 10 −6 ) 62 were eliminated.
Among these, nfa23460 , nfa38830 , nfa43970 , and nfa9390 exhibited highly significant differences (P < 0.000001).
These studies reported robust sample sizes, highly significant p -values ( p < 10−6), and statistically significant results in the largest included studies.
There was a moderate but highly significant correlation between GFP and SEAP expression (Pearson correlation coefficient = 0.72, p = 10 ‐6 ).
Circadian Profiles of XOR Isoforms and Melatonin-Cosinor Analysis The combined 24 h cosinor analysis revealed strong, highly significant rhythmicity in plasma melatonin (global p < 10 −6 ), with nearly identical acrophases in women and men (≈3.8–3.9 h).
The RR ratio was 0.29 (95% CI 0.18 to 0.48) and was highly significant ( P < .000001).
The association between Harvard step test and overweight was statistically highly significant (p=0.000001) with odds ratio of 24.65 (C.I. = 9.97; 68.68). 4.
SNP with call rates < 0.98, minor allele frequencies (MAF) < 0.03 and highly significant deviations ( P < 10 -6 ) from Hardy-Weinberg Equilibrium (HWE) were also excluded.
This effect is small; on average people get about 6% faster and spend about 1% less time buzzing, but highly significant ( p <10 −6 for both metrics, t -test).
Specifically, the evidence grading criteria were as follows: If the association was supported by a highly significant random-effects ( P < 10−6, a threshold considered to substantially reduce false positive findings) 10 – 13 , a sample size of more than 1000 cases, P < 0.05 in the largest study, I2 < 50%, absence of small study effects, a PI excluding the null, no evidence of excess significance bias, and P < 0.05
This is statistically highly significant ( P < .000001) in comparison with their mean preoperative score (M0-1/5).
As expected from the scatter, the correlation is small but highly significant ( F test: F (1,1320) = 246; R 2 = 0.16; p < 10 −6 ).
A Chi-square test showed these differences to be highly significant (χ 2 = 236.6; df = 17; p < 0.000001), confirming that germinated seeds are much more likely to occur on the side to which the ants do not have access.
This effect was highly significant and strongest in the proximal intestine (duodenum) where the number of stained PCs was reduced by half ( n = 7; P < 10 −6 ).
In contrast, highly significant differences were observed among the crop species (F 2,18 = 615.70, p < 0.000001; Table 1 ).
In this study, a highly significant ( P < 10 −6 ) and consistent decline was observed with the frequency of consumption. 250 Similarly, another case-control study in Puerto Rico ( n = 314) found that consumption of sofrito (a diet based on garlic and onion) was inversely associated with the occurrence of BC.
Even after accounting for phylum identity, the clustering was still highly significant (PERMANOVA P < 10 −6 ).
Overall, TIN‐signature genes show a highly significant ( P < 10 −6 ) enrichment for proximal SEs at all distance ranges measured (Fig. 5 C).
Differences between the autoimmune and control groups were highly significant ( P < 10 -6 ).
A highly significant positive correlation ( R = 0.43, P < 1 × 10 −6 ) between CHK1 and ZEB1 was observed in these breast carcinomas, in which 69% (89 of 129) of the tumors with high ZEB1 expression exhibited high CHK1 expression, and 77% (47 of 61) of the tumors with low ZEB1 expression showed low CHK1 expression ( Fig. 8b ).
For the average GR frequency, ANOVA also showed a highly significant effect of Condition ( F (4,200) = 325.9, G–G ε = 0.37, P < 1e−6, ηp 2 = 0.86; Fig. 2C ), but no effects of Group ( F (1,50) = 0.81, P = 0.37, ηp 2 = 0.02) or Group*Condition interaction ( F (4,200) = 0.32, P = 0.86, ηp 2 = 0.01).
We found a highly significant effect of TV group ( p < 10 −6 , Kruskal–Wallis test).