“highly significant”

The analysis of discriminance revealed a highly significant discrimination between diabetic patients and controls (Wilks lambda: 0.27; P < 0.000001).

These studies reported robust sample sizes, highly significant p -values ( p < 10−6), and statistically significant results in the largest included studies.

This difference was highly significant ( U -test, p < 0.000001).

We found the association between long sleep duration and increased mortality of lung cancer was highly significant in the random-effects models ( p < 1 × 10 −6 ).

In contrast, the majority (87%) of lncRNA hits identified were negative hits, and this enrichment in the lncRNA hit distribution was highly significant (permutation test p < 1 × 10 −6 ; Figure 3 A, right).

However, substantial between-country variability was observed, with highly significant differences in seroprevalence rates among country–decade combinations (χ2 ≈ 58,742, df = 23, p < 0.000001).

Consistent with the reduction in peripheral blood myeloid cells, the reduction in contribution from Kat6a E/E ;Kat6b E/E fetal liver cells to bone marrow CMPs, GMPs and MEPs was highly significant (all P <10 −6 ; Fig.

Lastly, kDGF was a highly significant multivariable predictor of a higher CCI, even after controlling for the four other significant multivariable predictors of this outcome ( p < 0.000001, Table 5 ).

This analysis reveals a difference in the K A / K S distributions between intact copies and retropseudogenes (which may show low K A / K S ratios by chance), with a highly significant excess of intact copies for K A / K S < 0.5 ( Figure 2 ; p < 10 −6 , Fisher's exact test).

Both values were highly significant when compared with the null hypothesis of no discriminative capacity (AUC = 0.5, p < 0.000001), indicating that the model performs markedly better than chance.

The CCorA model applied revealed that there was only a single canonical dimension between the two datasets, which was found to be very highly significant ( p <10 −6 , Wilks'-Lambda test); this first dimension corresponded to a canonical correlation of 0.99, which accounted for 67.2% of the total variance.

For HR2, PON1 activity was highly significant (protective) in an unadjusted model ( p = 10 −6 ); continued to be highly significant in a collection of models adjusted for gender, age, and a set of covariates added one-at-time; and finally remained significant ( p = 0.0003) in a model adjusted simultaneously for all covariates of the dataset (gender, age, UAE, past CVD, DM, apoB, use of statins, anti-hypertensives, smoking, ethanol use, and eGFR).

This is in accordance with Christoph et al .’s study, which reported a statistically highly significant ( P < 0.000001) result, showing non-buffered local anaesthesia to be 2.8 times more painful than buffered local anaesthesia.

Wave speeds were generally slower for adult Ceacam16 β gal/ β gal TMs (median: 4.55 m/s; iqr: 3.68–4.76 m/s; n = 49 measurements from five preparations) than for wild-type TMs (median: 5.88 m/s; iqr: 5.12–6.62 m/s; n = 50 measurements from six preparations), and the difference was highly significant ( p < 10 −6 in Welch’s t -test, with t = 6.55 and 68.1 (dof), computed using the Satterthwaite approximation ( 40 )).

The difference between means of traffic exposure groups was highly significant (Wilcoxon test, p < 0.000001).

However, it was highly significant ( P < 0.000001 ) in this study, and the direction of the regression line showed that the rare allele can increase the rate of multiple births.

3 Results 3.1 Nutrient main effects The overall mean effect of P was found to be highly significant (p < 1e −6 ) with an average yield gain of 251 kg ha −1 at an average rate of 15 kg P ha −1 .

The log10-transformed engorged larval weight was a highly significant predictor of the log10-transformed unfed nymphal weight, and the former explained 72.7% of the variation in the latter (Fig. 4 ; regression: F 1, 651 = 1738, p < 0.000001; correlation: r = 0.854, t = 41.859, df = 652, p < 0.000001).

There was a highly significant effect of Contrast (F (1,16) = 66.2,p<1e-6) on GR peak power, which is explained by a generally higher GR power in case of high, as compared to low, contrast.

Upon initial analysis, the storage process demonstrated a highly significant effect (Hotelling multivariate p-value = 1 × 10 −6 ).

The chi-square test for homogeneity of base frequencies across taxa was highly significant ( P < 0.000001 for all partitions examined, except with codon second positions P = 0.00926835), though the validity of this test is questionable because it does not take phylogenetic structure into account.

RESULTS AND DISCUSSION In accordance with previous studies (Bloom and Adami [ 5 ] and references therein), we found a highly significant correlation between the mean E of the complexes and their mean K (Pearson's R = −0.45, p < 10 −6 , n = 94, using K Candida-Saccharomyces ).

Highly significant differences ( P < 0.000001) were observed for both potassium and calcium relative to the other minerals (Fig. 10 ).

There was a highly significant positive correlation between the number of CRD components and the according cycle duration (Kendall’s tau = 0.38, p < 0.000001).

Following previous umbrella reviews, 13 we considered as convincing the associations with>1000 cases a highly significant association (p-value<1 × 10 −6 ), no large between-study heterogeneity, no evidence of excess significance bias or small study effects, and a 95% prediction interval excluding the null value.