“highly significant”

Specifically, its intercept was highly significant ( p = 9.32 × 10 −7 ).

MANOVA results on the PC scores were highly significant, highlighting the substantial differences between the morphological characters of the two species ( α < 0.001; P = 9.38e-07).

In contrast, the SLA measurements showed highly significant differences ( p = 9.47 × 10 −7 ) Figure 5 , with pairwise comparisons revealing significant differences between T1 and T2 ( p = 0.0000096) and between T2 and T3 ( p = 0.0004509), but no difference between T1 and T3 ( p = 0.5129).

The set of 495 genes overlapped between T98G and SK-N-SH cells showed a highly significant relationship with “Mitochondrial dysfunction” ( P = 9.53E-07), while the set of 196 genes identified only in T98G were less significantly related to “Mitochondrial dysfunction” ( P = 3.90E-03).

As expected, the difference in reporter expression between putative enhancers and negative control regions is highly significant ( P = 9.6 × 10 −7 by two-tailed t -test) ( Fig. 4B ).

A one-sided student T comparison of log-converted molar N/P ratios showed highly significant differences (p = 9.70 × 10 −7 ) between bacteria (geometric mean = 21.0, median = 23.3 mol N / mol P) and viruses (geometric mean = 9.25, median = 9.45 mol N / mol P), respectively.

At the genus level ( Supplementary Figure S3A ), the α-diversity pattern mirrored that of the species level, with all indices showing highly significant overall intergroup differences (Kruskal-Wallis test: all χ 2 ≥ 27.674, P ≤ 9.79 × 10 −7 ).

The results indicated that a cluster of highly significant SNPs represented by Chr2_67754173 ( p = 9.85 × 10 −7 ) was located downstream of Chr2T10180100, a gene encoding an LTP protein.

We observed a highly significant reduction in rolling in response to noxious stimuli compared to both controls when we inactivated the nociceptive class IV neurons (Chi square test, p< 10 −6 , Fig. 4A and 4B and Table S1 ) [2] , [29] , [40] .

Wave speeds were generally slower for adult Ceacam16 β gal/ β gal TMs (median: 4.55 m/s; iqr: 3.68–4.76 m/s; n = 49 measurements from five preparations) than for wild-type TMs (median: 5.88 m/s; iqr: 5.12–6.62 m/s; n = 50 measurements from six preparations), and the difference was highly significant ( p < 10 −6 in Welch’s t -test, with t = 6.55 and 68.1 (dof), computed using the Satterthwaite approximation ( 40 )).

This analysis revealed a highly significant negative correlation (Pearson r = − 0.95, P < 0.000001) between the two variables (Fig. 1 ), which suggests that the breeds with a low genomic diversity have a high proportion of amino acid-changing SNVs compared to those with a high genomic diversity.

Thus whilst there was no difference between males and females in the mean age of diagnosis for individuals homozygous for the more common ARE1 allele (56.5 years vs 56.7 years respectively), males carrying the less common ARE2 allele (heterozygotes and ARE2 homozygotes) had an earlier mean age of diagnosis (55.1 years) compared with females carrying the ARE2 allele (58.6 years) a difference of 3.6 years which was highly significant (p < 0.000001).

Remarkably, soyuz1 never contains any Proline; this depletion is highly significant (P = 10 −6 ).

A strong, highly significant correlation between the frequency of tracking interruptions with the right and left hand was found (Pearson correlation, r = 0.834, p<10 −6 ).

Differences between eukaryotes and bacteria, or between eukaryotes and the combined archaeal/bacterial data set, were highly significant ( P < 10 -6 that both represent samples drawn from the same population for each pairwise test). 5.

The behavioral phases of flies released at peak versus trough temperatures showed non-overlapping distributions with a highly significant difference (t-test P < 10 -6 ).

The observed enrichment (7 of 7) is highly significant (p-value = 1e-6), demonstrating that our serum proteomic analysis finds high concordance with validated assays.

Position-specific stability is correlated to a greater extent than is enthalpy or entropy Closer inspection of the correlation distributions suggested a second pattern: within homologous proteins, enthalpy and entropy generally did not exhibit correlations as great as those for stability (modes of 0.39, 0.50, and 0.61 respectively, Table 1 ; differences between these homolog distributions were all highly significant, exhibiting p <10 −6 as assessed by chi-square tests with 19 d.o.f ).

All other combinations of methods and scenarios had highly significant sensitivity (P < 1.0 × 10 −6 ) and specificity (P < 1.0 × 10 −6 ) compared to the baseline value 0.5, except for sensitivity of Lasso in Scenario 2 (P = 0.90).

The degree of reading impairment in patients, however, was significantly larger for passage than word reading, as evidenced by a highly significant Group (patients, controls) × Test (GORT, WRAT) (F(1,36) = 34.29, p = 10 − 6 ) interaction.

The vaginal shortening, mucosal atrophy, and bleedings were highly significant ( p < 0.000001) in the 5.0-Gy group after 5 years.

Validation of RNA sequencing results and identification of potential biomarkers A total of 29 genes with highly significant differential expression in the RNA sequencing analysis (Table 4 , FDR-adjusted p value < 0.000001 and FC > 4 or FC < − 4) were selected for further real-time PCR analysis (ABI7900HT Fast Real-Time PCR System, Life Technologies).

In all cases, the difference in the level of divergence between normal and tumor samples in each tissue and platform cohort is highly significant (Wilcoxon P value < 10 − 6 ; see Fig. 2 ).

One-way ANOVA for repeated measures followed by Tukey post hoc test revealed a highly significant difference ( p < 1 × 10 −6 ) between Fe-treated animals versus the other three groups (Fig. 1 b).

These clusters are robust to changes in network parameters and are highly significant (p-value < 1 x 10 -6 , permutation tests).