“highly significant”

6a and b , Action was associated with highly significant increases in offset (average offset ± SD: Action = −0.79 ± 0.25, Rest = −0.82 ± 0.26; t(108) = 5.35, p = 4.89 × 10 −7 ) and slope (average slope ± SD: Action = 1.14 ± 0.12, Rest = 1.08 ± 0.13; t(108) = 10.5, p = 4.19 × 10 −18 ).

A Kruskal–Wallis test revealed a highly significant effect of host species on individual parasite species richness (H = 29.07, df = 2, p = 4.9 × 10 − 7).

Synaptic transmission (SyT) ( Figure 3B , Table 5 ) was a highly significant sub-family of nervous system development and function (34 molecules, 23.3% of parent function; p = 4.9×10 −7 ) sharing 10 common genes with Ngs ( CNR1 , SHC3 , NLGN1 , ADRB2 , CACNA1A , CNP , and MPZ were elevated and TNF , FGF2 , and IL1B were suppressed by FD).

The combined allelic test was highly significant, with p = 5.0 × 10(-7).

In total, we found 27 genetic variants in VCAN that had highly significant associations ( p -value < 5 × 10 −7 ) with at least one of the 31 FA measures.

Importantly, with these corrected numbers, the difference in motifs densities is highly significant – p-value < 5e-7, binomial test.

Strikingly, this height separation was highly significant ( p = 5 × 10 −7 ) in interfaces with the negative OVCAR-3 cells, while either not significant or of much lower significance in the positive cells ( Figure S5M ).

Adding a large excess of non-labeled affibody molecule resulted in a highly significant (p < 5 × 10 −7 ) reduction of cell-associated activity.

Among the significant SNPs, only 21 showed highly significant associations (P ≤ 5 x e-07), and these were with three traits, two production traits that are precise measurements (MILK and FAT) and the third trait which has subjective, but well defined measurements (ANG).

The model demonstrated good discriminative performance at 12 months, with a concordance C-index of 0.884, and was highly significant overall χ 2 = 44.18, 8 df; P = 5 × 10 −7 .

Purifying selection is highly significant for all models ( P ≤ 5.0 × 10 −7 , Z-tests) (Supplementary Fig. 1 ).

QC exclusion criteria for SNPs were genotype call rates <0.90, highly significant deviation from Hardy–Weinberg equilibrium ( P < 5 × 10 −7 ) and minor allele frequency (MAF) < 0.005.

In the two large UK control samples, for example, there was a highly significant ( p = 5 × 10 −7 , using an exact implementation of the Cochran–Armitage trend test) difference in allele frequencies between UK1 (recruited exclusively in Scotland) and UK2 (recruited throughout the UK), which made us consider the possibility that this variant showed variation in allele frequency along the south–north cline as previously described in the WTCCC study and others [ 16 , 23 – 26 ].

The PPI enrichment score was statistically highly significant P = 5.01 × 10 –7 indicating strong interaction.

When analyzing the results by APL1A allele, only the APL1A 2 allele displayed a consistent protective effect, because the global silencing of all APL1A alleles caused a highly significant increase of infection prevalence only among carriers of the APL1A 2 allele ( p = 5.07e-07; Table 1 ).

This reduction was highly significant (Welch’s t = 8.63, df = 14.16, p = 5.1 × 10 −7 ).

Moreover, the regressions are highly significant, as reflected by F = 127.60 and p = 5.15 × 10−7 for cohesion and F = 69.26 and p = 8.32 × 10−6 for the internal friction angle.

Consistently, our data demonstrated a highly significant decrease in the expression of this direct MYC target in tumors treated with FPPa-OmoMYC relative to vehicle ( p = 5.16 × 10 −7 ) (Fig. 3c ).

Similarly, of the 17 genes in the “Chondroitin sulfate metabolic process,” which was highly significant in the ethanol-upregulated genes in the IP fraction ( p = 5.26 × 10 −7 ), and all ethanol-regulated genes ( p = 8.69 × 10 −4 ), 16 were upregulated by ethanol, suggesting that this process was highly upregulated in ethanol-exposed astrocytes.

hypogaea was included in the data matrix, the phi test was highly significant ( P = 5·273E-7; 148 informative sites; mean = 0·254; variance = 4·852E-4; observed = 0·147), reflecting the allotetraploid nature of this species, most probably comprising the A genome from A. duranensis and the B genome from A. ipaënsis.

As a result, we found sex differences at highly significant levels in the pheomelanin mol% ( p = 5.3 × 10 −7 ) and a significant difference in A650/A500 ( p = 0.0058).

The difference in EPS score, biofilm, and Nugent score between included and excluded patients was highly significant ( p = 5.4 × 10 −7 , p = 0.0005, and p = 0.0007; Additional file 4 : Figure S3A).

This effect was highly significant for both deletion and mutation of these sequences within both elements, albeit more severe for Sox10 -MCS7 (≥80% reduction in enhancer activity, p≤5.42×10 −7 ) than for Sox10 -MCS4 (50–80% reduction in activity, p≤2.11×10 −7 ).

ANOVA performed on the specimen-level average pore-size values ( P ̄ i j ) showed that extrusion temperature was the dominant and highly significant factor affecting pore size ( F = 19.9 , p = 5.439 × 10 − 7 ), whereas printing speed was also significant, although to a lesser extent ( F = 4.34 , p = 1.84 × 10 − 2 ).

Additionally, Label 12 showed highly significant results in the AF_L (F-statistic = 12.99599, p = 5.45E-07) and PYT_L (F-statistic = 10.1636, p = 1.48E-07) bundles. 3.3 Experiments on relapsing-remitting MS data Our pipeline was applied to the MS dataset for a set of relevant bundles in the context of MS studies: AF, ILF, IFOF, and PYT.