“highly significant”

Moreover, highly significant correlations Moreover, highly significant correlations were observed in the scatter plot of GS and MM within the MEbrown module (cor = 0.31, p = 3e − 7, Fig.

The difference between these proportion was highly significant ( χ 2 = 26.87, d.f. = 1, p < 0.0000003).

We used p-values defined by Lander and Kruglyak [ 17 ] to represent specific LOD score thresholds: (1) suggestive linkage with p value = 0.00074 and corresponding LOD = 2.2; (2) significant linkage with p-value = 0.00002 and corresponding LOD = 3.6; and (3) highly significant linkage with p- value = 0.0000003 and corresponding LOD = 5.4.

The correlation between the IC50 values of oxaliplatin and OSBPL3 expression was highly significant ( P = 3.01e-7, R = 0.368) ( Figure S5 A ).

Regarding the NSVB, there were highly significant differences between Hap1 and Hap2 ( P = 3.02e‐07) as well as between Hap2 and Hap4 ( P = 4.70e‐03), but there was no significant difference between Hap2 and Hap3 (Figure S5 ).

Particularly, the difference in a* among the 7 haplotype combinations was highly significant ( P = 3.06E-07), and the average of a* values were significantly lower in the pigs with the 11 and 13 haplotype combinations than those with 12 and 14 haplotype combinations.

However, there was a highly significant correlation between high FLAP expression and lower overall probability of survival in the 720 patients with lung adenocarcinoma ( P = 3.1 × 10 -7 , HR = 1.86) (Figure 1C ).

This SNP also exhibited a highly significant association with gestational age at delivery ( P = 3.1 × 10 −7 ).

The strongest iHS signals were detected on the X chromosome in SAR_M, where two closely spaced intergenic SNPs showed highly significant values (−log P value > 6.5) at approximately 44.6 Mb ( Figure 1 ).

Using this combination of methods, highly significant ( P <3.17×10 −7 ) population-specific sweeps pointing out to candidate genes and pathways that may be involved in beef and dairy production were identified.

We observed a highly significant shift in the distribution from expectation (p = 3.27x10 -7 ).

For the average ratio of the number of hospitals and hospital beds, the public sector exhibited a negative, moderate, and statistically significant trend (τ = −0.400, p = 0.0122), whereas the private sector showed a positive, highly significant trend with excellent strength (τ = 0.809, p = 3.338 × 10 −7 ).

3 RESULTS 3.1 Lesion healing scores There was a highly significant Treatment × Day interaction ( p = 3.4 × 10 –7 ), indicating differing lesion healing score time courses across the three treatment groups.

These two highly significant SNPs (rs10842383 near LINC00477 , P =3.45 × 10 −7 and rs2680344 in HCN4 , P =4.34 × 10 −7 ( Supplementary Table 12 ) had large opposite effects on atrial fibrillation, while both decreased HRV.

When applied to analysis of genetic homogeneity, blacklists allowed identification of highly significant STAT1 enrichment in 209 patients with chronic mucocutaneous candidiasis (p = 3.46x10 -7 ).

When PFS was compared between these two subgroups, we found a highly significant difference (Cox p = 3.46e-07, hazard ratio (HR) = 6.7; Fig. 2 a).

In contrast, when ESS was present, there was a highly significant association between comorbidities and death (Fisher’s exact test, p = 0.00000035).

One-way analysis of variance (ANOVA) indicated that fiber content had a highly significant effect on the peak stress of the specimens (F(4,10) = 68.71, P = 3.58 × 10 − 7).

This identified 82 significantly enriched GO terms ( Table S3 ) spanning broad aspects of plant biology, of which the top 25 Biological Process terms are presented in Figure 3 A, including highly significant categories such as cellular process (GO:0009987; adjusted p = 3.6 × 10 −7 ), metabolic process (GO:0008152; adjusted p = 9.9 × 10 −6 ), biological process (GO:0008150; adjusted p = 1.3 × 10 −5 ), and cellular metabolic process (GO:0044237; adjusted p = 2.0 × 10 −4 ).

The poor survival by high fetuin-A expressing tumor cells was highly significant in poorly differentiated gastric tumor cells (overall survival log rank P = 3.6 × 10 -7 ) [ 60 ].

The association between this SNP and HDL-C levels is weak when considering only allelic variation ( P = 0.98) but becomes highly significant when evidence from the genotype and the estimate of local ancestry is combined ( P = 3.6×10 −7 ) ( Table 4 ).

Several immuno-active genes demonstrated highly significant correlations between methylation and gene expression in IBD, in particular OSM: IBD r = −0.32, p = 3.64 × 10 −7 vs non-IBD r = −0.14, p = 0.77].

As a result, the scoring system by the combination of features with the top five highest absolute values of importance was highly significant (P-value = 3.692e−07) and a reasonably simple equation in the order of early-CRT Monocyte count , Distance from anal verge , early-CRT PLT , early-CRT Neutrophil count , and early-CRT Eosinophil count (Equation 5) was formed.

There was a highly significant enrichment of methylation changes around GWAS single nucleotide polymorphisms ( P = 3.7 × 10 −7 ), notably the HLA region and MIR21 .

We took advantage of the fact that 72 of the GII bulls had non-overlapping sets of GIII sons in H and NZ, to estimate the repeatability of GRR as the correlation between these independent measurements, yielding a highly significant Spearman's correlation coefficient of 0.58 (p<3.7×10 −7 )( Figure S4B ).