“highly significant”

We found marginally non-significant support for two-rate models for binary (i.e., presence or absence) conjugation ( P = 0.059; Likelihood Ratio Test) and highly significant support for two-rate models for SAM ( P = 1.58e-07; Supplementary Table 4 ).

Because one individual with Dup7 included in this analysis was treated with growth hormone during childhood, we repeated the analysis testing for association of AAM with 7q11.23 copy number excluding this individual, and the results were largely unchanged and remained highly significant (F = 20.55, η 2 = 0.41, p = 1.6x10 −7 ).

In the early infection group at 15 °C, a highly significant difference was observed between acute and control treatment groups ( p = 1.6 × 10 −7 ), indicating that these groups had distinct effects on mortality.

This difference is highly significant (p = 1.639e-07).

For classification accuracy, the difference was not statistically significant for the paretic arm model ( p = 0.8923) or the combined arms model ( p = 0.0907) but was highly significant for the non-paretic arm model ( p = 1.695 × 10 −7 ).

For each parameter and across the 1000 parameter sets, f del shows a highly significant correlation to S , but one that is only modest in value for some parameters (Spearman’s R = 0.16–0.76, P < 1.7×10 −7 , n = 1000 for all parameters), illustrating that S cannot generally substitute as a measure of f del .

Alpha‐power shift can discriminate seizure control subgroups An exploratory LDA with 10‐fold cross‐validation achieved the following performance parameters (mean ± SD [95% CI]): sensitivity of 71.2 ± 3.9% [63.5%, 78.8%], specificity of 79.6 ± 2.2% [75.2%, 83.9%], and AUC of 78.8 ± 1.0% [67.7%, 89.8%], which was highly significant ( z ‐test, P = 1.7 × 10 −7 ).

In contrast, defining influenza infection more loosely based on whether a participant reported having flu-like symptoms in the 2019–2020 or 2020–2021 flu seasons (43,956 cases versus 250,673 controls) led to attenuated effect sizes but still highly significant associations: OR = 0.93 and P = 1.7 × 10 −7 for ST6GAL1 , and OR = 0.95 and P = 4.0 × 10 −11 for B3GALT5 (Fig. 2 ).

One-way ANOVA confirmed highly significant differences across doses (F(5,12) = 47.4, p = 1.7 × 10 −7 ), with Tukey’s HSD post-hoc tests revealing robust separation from 2 Gy onward.

When we compared our promoter and gene body associated VMGs (271 genes) with that of Harris, we found highly significant overlap of 43 genes ( P = 1.75 × 10 −7 , hypergeometric test).

In the case of Apoc3 , while there was no significant eQTL in liver, there was a highly significant eQTL in adipose tissue ( P = 1.8 × 10 −7 ) (supplemental Table S3).

[ 24 ] is also highly significant (OR = 3.1, P value = 1.8e−7).

We found a highly significant association between the increase in WAT ferritin levels and improvements in insulin sensitivity (FTL, P = 1.81 × 10 −7 ; and FTH1, P = 4 × 10 −7 ) ( Fig. 5, A and B ).

4 and supplementary table S11 , Supplementary Material online), and a simple permutation test shows this observation to be highly significant ( P = 1.9 × 10 −7 ).

Activity An RM-ANOVA revealed highly significant effects for both treatment (F(7, 48) = 9.66; p = 1.95 × 10 −7 ) and the interaction between treatment and time (F(35, 240) = 2.68; p = 5.61 × 10 −6 ) on locomotor activity (LMA), as defined in the Methods section.

The association between MRS and ΔBMI in non-smoking samples is highly significant (n = 1,243, β = 0.045, p = 1.96 x 10 −7 , R 2 = 0.021), albeit with a slightly diminished effect size estimate (empirical p < 0.0061, calculated using 10,000 random samplings of 1,243 FHS samples) compared to association in all samples (n = 1,508, β = 0.055, p = 5.80 x 10 −12 , R 2 = 0.031).

Twelve genes were common to both sets, a highly significant overlap (p = 1.989284e-07 hypergeometric test) (XLS) Click here for additional data file.

While rs7041 only had a modest statistical association in our single-SNP GWAS ( p =2.8×10 −4 for antenatal and p =0.01 for cord blood), the results for haplotype association ( Table 4 ) were highly significant (ANOVA p =2.0×10 −7 for antenatal and p =3.0×10 −6 for cord blood).

However for responses evoked by octopamine and dopamine the correlation is high and highly significant (OA: r s = 0.93, p = 2e-7 [n = 24 responses from 6 oocytes]; DA: r s = 0.97, p = 2e-7 [n = 14 responses from 5 oocytes]).

Lab values of included intervals ), mean baseline HIC and SF were not different (p < 0.7 and p < 0.2 respectively); overall, HIC and SF worsened during deferiprone treatment (p < 0.001 and p < 0.0003, respectively), and improved during deferasirox treatment (p < 0.001 and p < 0.0001, respectively); follow-up HIC values differing between deferiprone and deferasirox monotherapies were highly significant (p < 0.0000002).

In particular, we found a highly significant positive correlation between disease and the Magenta (comprised of 576 genes) module eigengene ( r = 0.67, P <2 × 10 -7 ), the Brown (2,502 genes) module eigengene ( r = 0.6, P <6 × 10 -6 ), the Light-Cyan (349 genes) module eigengene ( r = 0.42, P <0.002), and the Grey60 (based on 216 genes) module eigengene ( r = 0.47, P <8 × 10 -4 ).

Total between-groups Q, shown at the bottom of Table 8 (Q = 33.93, df(Q) = 3) indicates that there is a highly significant difference between the effectiveness of the four meditation categories on PTSD ( p < 0.0000002). 3.1.

Indeed, 69% of genes analyzed showed negative Z -scores in whole blood relative to other tissue types, which is highly significant ( p < 2 × 10 −7 , assuming a binomial distribution).

However, according to the Spearman rank correlation analysis the expression of IGF-IR and VEGFR-2 was highly positively correlated and statistically highly significant (r = 0.745 and p = 0.0000002) ( Figure 7 ).

Simple linear regression revealed a highly significant relationship ( p < 0.0000002) between road kill samples collected and rabid meso-carnivores detected in 2016 (r 2 = 0.86).