The difference is highly significant across repeated experiments with different set of random inputs ( p < 10 −8 , n = 10, paired t -test).
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Both the integrated fluorescence intensities, which represent the amount of DNA per nucleoid ( Figures 3B,D and Table 1 , columns 11 and 12), and the measurements of nucleoid lengths ( Table 1 , columns 13 and 14) indicate that the difference in DNA between small and large deeply-constricted cells at the fast growth rate is highly significant ( p < 10 -8 , as determined by a two-tail t -test); at the slow growth rate, the difference remains significant, but just barely ( p = 0.035).
4b and Supplementary Data 2 ), which is highly significant (Binomial Test P -value < 10 −8 ) and suggestive of their functional importance.
All intereye correlations were highly significant ( P < 1x10 −8 ).
The role of recombination in mixing the genetic pool of HCMV at the whole genome level is confirmed by a highly significant rejection of the pairwise homoplasy index (PHI) test ( Bruen et al. 2006 ; P < 10 − 8 ).
All of these predictors gave highly significant ( P < 10 -8 ) improvements over random pairs.
All enrichments for GO ontologies representing these six biological processes were highly significant; P <10 −8 .
The analysis demonstrated a highly significant result (test statistic = 0.0, p < 0.00000001), indicating that median stent migration was greater than zero and that measurable displacement occurred between the three-month and one-year intervals.
Serum levels of 10 biomarkers correlated (r > 0.2, P < 0.05) with the level of fT4 and 12 with the level of TRAb (Supplementary Table). Six biomarkers showed a highly significant increase ( P < 1 × 10 −8 ) between patients with GD and HS ( Fig. 2 ), most significant for TNF receptor superfamily member 9 (TNFRSF9).
A burden test adjusted for sex and the first five principal components for the 15 loci revealed highly significant enrichment in rare homozygous, potential compound heterozygous, or hemizygous variants in patients relative to controls (P = 1 × 10 −8 ; odds ratio = 26.6; 95% confidence interval = 7.3–96.6), with 12 carriers among the patients (10.7%, including four homozygotes, one potential compound heterozygote, and seven hemizygotes) vs. three (0.25%, two homozygotes, one hemizygote) among the controls.
Statistical tests showed that the covariance was highly significant in all of the species (Spearman test; P <10 −8 ).
cellulosilyticus exhibited a highly significant increase in abundance (p < 1 × 10 −8 ) in Apoe −/− mice, and R. intestinalis had a slightly higher (p = 0.025) relative abundance in mice gavaged with the combination of bacterial species compared to Apoe −/− control mice.
Moreover, there was a highly significant correlation (p<10e-9) between the Information and both the convergence rate (the percentage of trajectories that converge into the target) and the inverse of the mean number of steps to convergence of the off-line dNI trajectories ( Figure 4E–F ).
We listed highly significant genetic effects of loci (−Log 10 P >8.0 and >1.0%, >0.5%) and consistent loci with environment interaction which were stable in a particular ecological area across at least two years for lint yield and three yield traits ( Figure 1 , Table 2 – 5 ).
A highly significant association was observed between haplogroup and both language class (Cramer's V = 0.20, p<10 −8 , Table 1 ) and language group (V = 0.41, p<10 −8 , Table S3 ).
We chose SNPs for the model that were highly significant and not in strong LD with each other (i.e., P < 10 -8 for r 2 between SNPs).
The difference in FF between all of the identified AEN and AIN groups was highly significant ( p < 10 −8 , ANOVA post-hoc Tukey test).
These genes were either associated with resistance to both lead and cadmium in both sexes or had highly significant ( P < 10 −8 ) effects in any one condition.
Biological underpinning of the shared genetic components—translational evidence from mice For each of the Master PCs, the top-500 correlations across all records of the Amygdala Cohort Database, ranked by the Genetic Correlation (Spearman's rho), were strong (absolute value ranging from 0.7 to 0.9), and highly significant ( p < 10 −8 , Supplementary Tables 5, 6 ).
The results show also a highly significant p value for vessel diameter in the DCP in SWS patients compared to controls ( p = 0.00000001) ( Table 2 ).
Indeed, Pearson correlation between E2F1 and CCND1 is close to 0 and not statistically significant ( P = 0.4) while the MI is highly significant ( P = 10 − 8 ).
Pearson correlation coefficient between replicate transfections was highly significant, reaching 0.88 ( P < 10 −8 ); however, the overall correlation between exogenous and endogenous NSE levels was only 0.35 ( P < 0.01).
We found that G→T transversions were over-represented in both the maize and sugarcane evolution experiments, and that this over-representation was highly significant when either the MSV-Tas sequence dataset was analysed alone (chi square p < 10 -8 ) or when all the mutation data from both experiments were considered collectively (chi square p = 5.4 × 10 -7 ; Table 1 ).
Gene Ontology analysis of this cluster reveals a highly significant ( P ≤10 −8 ) number of genes that are associated with cell defense response ( Figure 5D ).
There was no significant difference in the family effect between years (interaction family × year not significant; LRT: χ 2 = 1.2; df = 2; p = .552), but the family effect was highly significant ( χ 2 = 32.6; df = 1; p = 1 × 10 ‐ 8 , Table S2 ) and the heritability of the sensitivity to vernalization was 0.19 (±0.04) (Table 2 ).