We found that recombination happened more often in the middle of core regions at a small but highly significant level (Kolmogorov-Smirnov test; p-value=8.8e-09).
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The correlation between these phenotypes is numerically small ( r 2 = 0.03) but highly significant ( p = 8.89 × 10 − 9 ), likely due to the large sample size.
We again confirmed a highly significant association in an overall analysis stratified for the populations, with an odds ratio of 0.46, 95% CI 0.35–0.60, P = 8.94 × 10 −9 (Table 1 ).
Both skewness and CV successfully detected microtubule bundling during PPB formation, with the skewness and CV values for differences between the images with and without bundling being highly significant, but more so for CV (Mann–Whitney U-test, P = 8.947e−09 for skewness and P = 6.202e−14 for CV; Fig. 3 B, C, Supplemental Fig. 5 B).
CeaGO analysis reported "chemokine" as highly significant from a statistical perspective ( p -value = 9e-09 for cluster NO. 1, and 3.4e-06 for cluster NO. 2).
Both allelic and genotypic comparisons between Patna and Vaishali districts were highly significant (allelic χ 2 2 = 37.1, P = 9 x 10 −9 ; genotypic: χ 2 3 = 21.4, P = 9 x 10 −5 ).
Two microRNAs, miR-29a and miR-29c, were disclosed and further meta-analysis of the six mRNA expression datasets showed that these two microRNAs were highly significant based on the Fisher p-value combination (p = 9.14×10 −9 for miR-29a and p = 1.14×10 −6 for miR-29c).
The ANOVA of flaA -SVR groups from caecal isolates demonstrated a highly significant difference in the numbers of isolates between flaA -SVR groups ( P = 9.37 x 10 −9 ).
Among them, the MCV level was highly significant (nominal p = 9.8×10 −9 ) in association with the DYRK1A -SNP1 (c.2989 G<A), and explained 4.9% of the phenotypic variance.
5e ), and the difference in means was overall highly significant ( p = 9.95 * 10 −9 , two-sided t -test based on the data in Fig. 5d ).
Biological underpinning of the shared genetic components—translational evidence from mice For each of the Master PCs, the top-500 correlations across all records of the Amygdala Cohort Database, ranked by the Genetic Correlation (Spearman's rho), were strong (absolute value ranging from 0.7 to 0.9), and highly significant ( p < 10 −8 , Supplementary Tables 5, 6 ).
We show this to be a highly significant ( p < 10 –8 ) result with a large effect size.
In contrast, HGP treatment induced a highly significant increase in WISP2 expression ( P < 10 −8 ) [ 40 ], but reduced IMF deposition [ 17 ], the opposite of what would be predicted based on the analysis of expression of WISP2 and the IMF 5 gene set genes in WxH and PxH genotype animals.
We observed a highly significant main effect of waveform class on decoding performance for each motor feature (median improvement in R 2 was 0.15 across datasets/motor features; p < 1e-8 for every dataset/motor feature combination, Bonferroni adjusted for multiple comparisons).
In new Figure 3D , the cluster area plot shows a visible and statistically significant difference in ZitP cluster area between the swarmer and stalked poles as supported by the highly significant difference observed (p < 10 -8 ).
Since the distributions of time budget left is not Gaussian, we performed a Wilcoxon signed rank test comparing the both distributions, which was also highly significant ( z = 5.44, p < 10 −8 ).
These measurements, distinguishing biopsy-positive from biopsy-negative men, were highly significant ( P < 10 −8 ; 100% sensitivity and 81.8% specificity).
This difference is significant for six of the 12 genes ( p <0.05), and highly significant when all 12 genes are pooled ( p <10 −8 ; Table 3 ).
A highly significant association was observed between haplogroup and both language class (Cramer's V = 0.20, p<10 −8 , Table 1 ) and language group (V = 0.41, p<10 −8 , Table S3 ).
In terms of number of targets predicted, there was highly significant difference between conserved and soybean-specific miRNA families (Student’s T-test, P < 10 -8 ).
Moreover, there was a highly significant correlation (p<10e-9) between the Information and both the convergence rate (the percentage of trajectories that converge into the target) and the inverse of the mean number of steps to convergence of the off-line dNI trajectories ( Figure 4E–F ).
The difference in FF between all of the identified AEN and AIN groups was highly significant ( p < 10 −8 , ANOVA post-hoc Tukey test).
The analysis demonstrated a highly significant result (test statistic = 0.0, p < 0.00000001), indicating that median stent migration was greater than zero and that measurable displacement occurred between the three-month and one-year intervals.
These genes were either associated with resistance to both lead and cadmium in both sexes or had highly significant ( P < 10 −8 ) effects in any one condition.
This enrichment is highly significant, as only 5.5% of informative sites overlap a DSB hotspot (p < 10 −8 , calculated from 10 8 permutations; see ‘Materials and methods’—‘Inclusion criteria’).