“highly significant”

In the absence of LD pruning the KS p-value was diminished after adjusting for PRS, but still highly significant (KS p-value = 2.5 × 10 −11 versus 2.2 × 10 −14 , Fig 4 ).

counts of concordant/discordant pairs) was very pronounced (odds = 5.36) and highly significant ( P = 2.5E–11).

Both predictors were found to be highly significant, where a strong positive effect on recovery success was observed for raw read count (OR = 2.60, 95% CI: 1.97–3.45, p = 2.5 × 10 −11 ) (Figure 6A ), indicating that each 10‐fold increase in sequencing depth approximately tripled the odds of successful barcode recovery.

Visual Analogue Scale (VAS): The mean pain score decreased notably from 8.00 to 6.20, with a highly significant change ( p ≈ 2.55 × 10 −11 ), indicating substantial pain relief over time.

2016 ) of CA1 transcriptional alterations following a contextual fear conditioning task at this same time point, finding a highly significant overlap between our data set and theirs (Fisher's exact test, P < 2.66 × 10 −11 ).

2a ) and the analysis of variance revealed very highly significant differences between accession groups ( P = 2.666e-11).

The overlap of our Mcm1 genome-wide binding data in yeast state cells with a previously published Mcm1 ChIP-CHIP done on tiling microarrays is highly significant (pvalue = 2.7E-11) with 198 genes common between studies [ 8 ] (Fig. 3D ).

The difference between the average random result from 100,000 simulated experiments (40 matches) and the real result (76 matches) was highly significant ( p = 2.78*10 − 11 ).

Planned paired t tests show that the difference in accuracy between HSF and LSF images is highly significant without contrast normalization ( t (20) = −13.11; p = 2.79 × 10 −11 ) but not when normalizing the filtered images for RMS contrast ( t (20) = 0.90; p = 0.378).

Statistical analysis using the nonparametric Kruskal-Wallis test yielded a highly significant difference among the three inhibitors ( P -value = 3.048e-11), suggesting that the time-to-onset of MSAEs varies significantly among these drugs.

One-way ANOVA confirmed a highly significant overall difference among the groups ( p = 3.06 × 10 −11 ), and subsequent post hoc comparisons indicated that each decalcification treatment resulted in significantly lower density values than the controls ( p < 0.0001).

These differences were highly significant ( p = 3.08 × 10 −11 for OCI-Ly19 vs.

One-way analysis of variance (ANOVA) showed that differences of the mean normalized luciferase responses are highly significant (p = 3.17×10 −11 for the interaction with TRAF6).

Highly significant gene ontology (GO) terms were identified for the DPC associated modules including “dendrite morphogenesis” (“blue” module; P -value = 3.22E-11), “negative regulation of synaptic transmission” (“black” module; P -value = 6.29E-09), “negative regulation of axon extension involved in axon guidance” (“red” module; P -value = 3.64E-09) and “embryonic organ morphogenesis” (“green” module, P -value = 1.79E-11), suggesting that the large changes in 5hmC across fetal brain development contribute to the regulation of relevant biological processes.

This difference was highly significant ( T -test: t = -8.1516, DF = 58, p -value = 3.344e–11) (Fig. 5d ).

Of the 29 proteins that we identified as interacting with DDX6 ( Table 1 ), 13 were found to be members of this core set of sumoylated proteins, representing a highly significant enrichment in comparison to the human proteome (hypergeometric test, p = 3.4 × 10 −11 ) ( Figure 5 C).

The highly significant p-values for both Dd3937 (p = 3.42e-11) and WPP14 (p = 3.36e-12) strongly suggest methyl-accepting chemotaxis genes are highly enriched among the predicted host-microbe interaction factors.

On the contrary, palmitoleic acid showed several highly significant correlations with anthropometric features (BMI: r = 0.408, p = 3.5 × 10 −11 ; waist/height ratio, fat mass: r = 0.402, p = 3.35 × 10 −10 , fat-free mass) and with systolic (SBP) and diastolic BP (DBP).

Type II ANOVA statistical analysis revealed that pillar pitch was a highly significant determinant of viral titer (F(3,36) = 37.54, p‐value = 3.53 × 10 −11 ), indicating that average log 10 (PFU/mL) differed strongly among surface pitch conditions relative to flat acrylic.

For example, in the nup170 Δ strain these tests show a highly significant enrichment of upregulated genes within 25 kilobases (kb) of the telomere (hypergeometric test P -value = 3.54e-11).

When we ran a binary logistic regression analysis with group (LBD versus atypical PS) as a dependent variable and both DDC level and SAA status as independent predictors, we found that SAA was a highly significant variable that discriminated LBD from atypical PS(SAA: β = 5, P = 3.6 × 10 −11 , AUC = 0.95, sensitivity = 0.93, specificity = 0.93), in contrast to DDC ( β = 0.6, P = 0.01, AUC = 0.73, sensitivity = 0.37, specificity = 0.89) (Extended Data Fig. 4a ).

cutoff 0.5: https://www.rdocumentation.org/packages/genefilter/versions/1.54.2/topics/nsFilter This analysis resulted in just 213 unique genes that were differentially-expressed at a nominal p-value<0.05, 35 of which had a fold change in expression >1.5 (the 24 genes from Table 2 as well as Psg25 , 1700047G07Rik , Ugt2b5 , Vmn1r86 , Olfr493 , Olfr295 , Vmn1r37 , Olfr800 and Fpr2 ); for the 213 genes, the KEGG pathway ‘olfactory transduction’ remained highly significant (p=3.6x10 -11 ), as did the GO biological pathway terms ‘G-protein-coupled receptor signalling’ and ‘sensory perception of smell’ (p=7.9x10 -12 and p=1.2x10 -12 respectively) and the GO molecular function terms ‘G-protein coupled receptor activity’ and ‘olfactory receptor activity’ (p=9.6x10 -17 and 2.4x10 -13 respectively).

The accuracy T-test shows a highly significant difference (t = 14.84, p = 3.65e-11) in accuracy between M-Net and SOTA CNNs.

Highly significant interactions ( p < 3.66 × 10 −11 ) were predicted in decreased abundance proteins when compared to increased abundance proteins ( p < 1.91 × 10 −7 ) ( Figure 4 A,B).

For “external oppression or challenge,” 28 out of 58 tragic descriptions met the consensus criterion, compared to 0 out of 59 joyful descriptions, yielding a highly significant association ( p = 3.68 × 10 −11 ).