“highly significant”

The differences of the expression distributions between bound and unbound genes for all the transcription factors under study are highly significant (p-value<1e-15).

This showed a highly significant increased risk of MS associated with smoking with no significant statistical heterogeneity (RR 1.48, 95% CI 1.35–1.63, p<10 −15 , heterogeneity: χ 2 = 7.38, p = 0.60; figure 1 ).

The average correlation coefficient was 0.511 (standard deviation 0.113) which is highly significant ( P <10 −15 ) for the average protein length of 217 residues in the PDB set.

Student's t-test analyses show highly significant differences in the overlap of p12 with chromosomes between mitotic and interphasic cells for the 1xMycR virus (p<10 −15 ); similarly highly significant differences in the overlap were observed amongst the 1xMycR or 1xMycR/PM14 viruses in mitotic cells (p<10 −17 ); and an absence of such differences for either the two viruses in interphasic cells or for the 1xMycR/PM14 in mitotic and interphasic cells (p>0.4).

This result was consistent across feature levels and parameter settings, and is highly significant for all tests: that is, for every comparison between modular subnetwork features and gene features, we have P < 10 -15 .

The baseline method ROTS that ignores longitudinal trends also performed well with an IQR mean pAUC of 0.941, while the difference to the best performing method RolDE was highly significant ( p < 10 −15 ).

In the case of pairs corresponding to Cluster II, there was a clear inverse relationship between ω and t , with a highly significant statistical correlation ( r = -0.9032, P < 10 -15 ).

Comparing between a paper’s date of publication and its citation count reveals there is a low anti-correlation (−0.2) but highly significant between the two (Pearson product-moment correlation test P -value < 10 −15 , Supplementary Fig.

We found a highly significant correlation between promoter CpG O/E and 3' UTR length (Spearman's ρ = 0.24; P < 10 -15 ), indicating that the negative correlation pattern between promoter region methylation and number of miRNA target sites still holds in mice.

We also plotted the USP51 protein score versus the DGCR8 protein score for individual patients, which revealed a highly significant correlation (Pearson R 2 = 0.52, P < 1 × 10 −15 ; Supplementary Fig. 7c ), indicating the relevance of the identified regulatory mechanism in human cancer.

2 ), the global model was also highly significant (P < 10 −15 ) and explained 64.4% of the total deviance.

2c and Supplementary Data 2 ); pairwise comparisons were likewise highly significant ( n = 398 and 753, respectively, both p < 10 –15 ; Supplementary Fig. 4 ).

1d ) fitted the standard logistic population growth model well and displayed highly significant increase in biomass ( p < 10 –15 , likelihood ratio test), which is typical for the growth of microorganisms under favorable conditions 23 .

In contrast, a robust and highly significant increase was found in the dopaminergic neurons of α-Syn zebrafish under identical conditions (α-Syn post-MPP + 1.73 ± 0.09; p < 10 −15 vs . baseline, 2-way ANOVA with Tukey multiple comparisons test; Fig. 5 E).

ANOVA indicated that the overall regression model was highly significant (F = 699, p < 1 × 10−15).

picta as indicated by the highly significant logistic regression of male proportion against wCTUs (Z = −15.15, P < 1 × 10 −15 ) (Fig. 3c ).

First, they represent a consistent and highly significant (Wilcoxon test P < 10 −15 in all growth phases except LS) decrease in expression across hundreds of rpoS regulated genes, in all five growth phases.

The differences in temporal variability are highly significant (medians for sources vs. sinks, 0.022 vs. 0.016, p < 10 −15 , two-sided Wilcoxon rank-sum test).

The difference in LAMconcentration between the cases and controls was highly significant [ P < 1 × 10 −15 , n = 101, Wilcoxon signed-rank test; difference in location estimate, −247.318; 95% confidence interval (CI), −351.3 to 200.8; Fig. 3 ].

Results A highly significant variation among all individuals and within each breed was observed in the number of duplications ( P < 10 −15 ) and in the number of deletions ( P < 10 −15 ).

A t -test between the UTR lengths in the “average fold-change” group and the “high fold-change” group was highly significant, with a p -value < 10 −15 .

The difference between imprinted and other monoallelically expressed genes was highly significant ( p < 10 –15 ), which is consistent with the imprinting mechanism, when an allele is expressed or silenced due to its parental origin without regard to the presence of a specific base.

The differences in median PEN MICs were highly significant ( P < 1 × 10 −15 for all pair-wise comparisons by Mann-Whitney U test).

We find a highly significant negative correlation between the two measures (linear regression: R 2 =0.34, P <10 –15 ), which is illustrated in Fig. 4 .

We have to reject the null hypothesis and this result is highly significant ( p < 10 −15 ).