“extremely significant”

For the spotted shins, six significant SNPs were identified, using a significant p -value ≤ 3.94885 × 10 −9 as the threshold, while one extremely significant SNPs was identified using a p -value ≤ 7.8977 × 10 −10 as the threshold.

Considering the total number of unique genes represented in the arrays as 10500, these overlaps were extremely significant (hypergeometric distribution p = 9E-10 and 2E-09, in that order).

There is one extremely significant correlation (adjusted p value < 10 −9 ) between class size and year level.

We performed a Chi-square test on this data, finding that the association between TP53 status and GS category was extremely significant ( p = 4 × 10 − 9 ).

The extremely significant difference ( P = 2.6964E-08) between them suggests the specificity of these genes to distinguish the diabetic PDAC patients from the non-diabetic cases ( Figure 4 ).

Protein-coding regions displayed 11.29-fold enrichment, 5’ UTR regions achieved 8.00-fold enrichment, while extended intronic regions showed 1.32-fold enrichment at extremely significant levels ( P = 2.92 × 10 –8 ), suggesting that these regions may participate in complex genetic mechanisms through regulation of gene expression or function.

Furthermore, we assessed prognostic differences between these two subgroups with a recurrence-risk analysis, and the difference between the two subgroups was extremely significant (log-rank p = 7 × 10 −8 ), with a C-index of 0.684 ( Figure 5 ). 3.2.3.

The identified lead SNP rs3732593 was extremely significant (P = 7.19 × 10 −8 ) in the discovery FHS sample but was only nominally significant (P = 0.04) in the replication sample.

Nevertheless, the observed degree of overlap was extremely significant (5 sites in both log-phase #1 and #2, p = 1e-7; 9 sites in both log-phase #1 and heat-shock, p = 3e-15; 14 sites in both log-phase #2 and heat-shock, p = 2e-18; all p -values computed by hypergeometric distribution), due to the vast number of possible nucleotides evaluated from throughout the transcriptome ( Figure 3 , Table 1 ).

It is worth also noting that the multivariate Cramer Test that detects differences in cytokine patterns was not significantly different between ND and PIH‐in group ( P = .087), while, as expected, the P ‐value between ND and PIH‐out was extremely significant ( P = .0000001).

3 C, the difference in cell uptake between test groups with and without magnetic field was extremely significant ( P = 1.94 × 10 −7 ).

Furthermore, we observed an extremely significant down-regulation of OsMADS1 (fold-change = 56.7 and p = 6.1 × 10 −7 ), which negatively regulates grain length [ 9 ] ( Figure 9 A).

A total of 40, 1, and 13 SNPs reached extremely significant levels in body length, body height, and total teat number traits ( P = 7.03E-7).

A total of three and six multi-trait QTL were identified under three metal conditions with extremely significant values, p = 7.4E-7 and 5.1E-15, and were closely positioned (MT1.1 for SL and RL; MT1.2 for SL, RL, and SDW) at 35.5 Mb and 38.4 Mb of chromosome 1, respectively.

Indicator Species Multi-response permutation procedures (MRPP) showed an extremely significant difference in species composition across an edge-to-interior gradient in an overall comparison (Table 2 , P < 10 −6 ).

Variance analysis of the response surface revealed that the significance of the TFC was influenced by the percentage of ethanol, which was extremely significant ( p < 0.0000014).

As this test was extremely significant (p-value = 2.2*10 −6 ), we rejected the null hypothesis and assessed the effect of the partial smoke-free legislation on AMI incidence, mortality, and case-fatality by negative binomial regression analysis.

But as we predicted, our RD analysis showed that RD>0.02 was extremely significant ( p = 2.81e-06, 5.12e-05, and 1.53e-07 in overall, control, and case populations, respectively, Table 6 ).

The average crown rump length of Hypox/Flox embryos exposed to hypoxia for 96 hours, from E8.5-12.5, was decreased by 34% to 5.7 mm (± 0.29, N = 5), which is extremely significant compared to 8.6 mm for Normox/Flox embryos (P ≤ 3.7 × 10 -6 ).

In terms of species diversity, the Shannon indices were significantly higher in high-richness samples of the stipe (7.237–7.377) compared to the pileus (1.730–5.832) and the hymenophore (1.483–4.249), with extremely significant inter-part differences ( p = 4.7 × 10 −6 ).

An association between cytoplasmic claudin 3 and nuclear Sip1 expression was extremely significant ( p = 0.0000053).

The significance tests of correlation coefficients revealed that the majority of the correlations between these genes were extremely significant ( P < 1 e − 5, Figure 5(b) ).

The factors affected the degree of Artemisia polysaccharide extraction differently, the primary term affected D (<0.0001) > C (0.0076) > A (0.0023) > B (0.384), the interaction AB, AC, AD, BC, BD were not significant ( P > 0.05), CD was significant ( P < 0.005), the secondary terms A 2 , B 2 , C 2 , D 2 were extremely significant ( P < 0.00001).

Not only that, the comprehensive effects revealed that the TC changes relative to baseline further became an extremely significant difference in both groups [MD = 3.34; 95% CI (1.88, 4.79); P < 0.00001].

These differences in Tables 1 and 2 are extremely significant ( p < .00001 based on χ 2 ).