“did not reach statistical significance”

After further division of the entire cohort by age, this difference did not reach statistical significance for patients younger than 80 years (age range, 28–79 years) ( P =0.246, Figure 2C ), but was again highly significant in the group of patients aged 80 years and older (age range, 80–99 years) ( P <0.001, Figure 2D ).

Two studies [ 23 , 30 ] were excluded and did not reach statistical significance (SMD –0.00; 95% CI –0.10 to 0.10; P <.001; I 2 =0%).

Analysis of the little data available on endothelial function [ 11 , 12 , 34 ] seems to confirm a beneficial effect of continuous treatment with PDE5i, although the data were almost entirely derived from ED patients [ 54 , 55 ], the effects did not reach statistical significance in patients with left heart disease, and there was very high heterogeneity (I 2 = 99%, P <0.001).

There were trends for differences between groups across multiple outcomes, but most did not reach statistical significance, except for a greater decrease in self-reported fat intake in the intervention vs. control groups (26.3% vs 10.6%, P = 0.001).

When results from three capsule isolations were analyzed and compared to that of the three EtOHp preparations from which the purified HMW O-Ag capsule was derived, the compositional FA differences were again observed, including: increased presence in capsule of 3-OH-16:0 ( Fig 3G , left; p<0.05) and C14:0 ( Fig 3G , center, did not reach statistical significance) and decreased presence of C16:0 ( Fig 3G , right; p<0.001).

Effects of VIL and NWT-03 supplementation in ZDF rats ( Table 2 ) GLP-1 levels trended higher (∼1.4-fold) after NWT-03 treatment (although this difference did not reach statistical significance), and were profoundly increased (∼5-fold, p<0.001) by VIL.

Although the difference in each condition did not reach statistical significance, the consistent trend across most conditions ultimately resulted in the average AUC of WARM being significantly higher than that of BASE ( p < 0.001).

Although this difference did not reach statistical significance, a significant main effect of time was observed (F(1, 28) = 15.00, p < 0.001, ηp 2 = 0.349; Figure 6 ), accompanied by a moderate effect size.

With the exception of the liver, where a tendential reduction in day 11 median virus titer did not reach statistical significance due to high variance in the therapy group, infectious virus load was found to be significantly reduced in spleen (P < 0.001) and lungs (P = 0.014) by 10 7 CD8-TCR NLV cells but not by 10 7 CD4-TCR NLV cells (P >0.05 throughout).

VO 2 max ranged from 40 to 65 mL/kg/min (53.8 ± 6.4) and 38–63 mL/kg/min (50.5 ± 7.0) for males and females ( p = 0.049), respectively, but did not reach statistical significance after the Bonferroni correction (p ≤ 0.001).

The associations between symptoms and all the remaining variables did not reach statistical significance (according to the Bonferroni adjusted level of p = 0.001). 3.4.

Although the improvement in NRI compared to the APPLE score in the training cohort did not reach statistical significance, the nomogram significantly outperformed the three scores on all metrics in the validation cohort (all P < 0.001).

This difference did not reach statistical significance after Bonferroni correction (α = 0.0167) . 1–5 years : AOR = 1.592 (95% CI = 1.270–1.789; p < 0.001), statistically significant after correction. > 5 years : AOR = 2.743 (95% CI = 1.625–3.891; p < 0.001), statistically significant after correction.

In relation to hospital type, there was variability in the availability of antidotes, but this did not reach statistical significance, except for deferoxamine (p < 0.001), which was available in all governmental hospitals but none of the private hospitals.

The adjusted OR (aOR) for coffee and green tea intake for periodontitis did not reach statistical significance in model 2, while that for mild soft drink was 1.16 (95% confidence interval (CI) = 1.11–1.21, P < 0.001) and that for heavy soft drink was 1.02 (95%CI = 0.96–1.09, P = 0.518) ( Table 2 ).

VEGF positivity was observed focally around endometrial vessels but did not reach statistical significance. Quantitative analysis confirmed significant increases in osteonectin (*** p < 0.001) and TNF-α (** p < 0.01) expression in the 30-min group (Fig. 8 ).

Shoulder movements, right wrist and right distal hand did not reach statistical significance. In the lower limbs, significant group differences were found for right ankle (p < 0.001), left ankle (p < 0.001), right distal foot (p = 0.001) and left distal foot (p = 0.002).

Although this difference did not reach statistical significance, it is directionally consistent with the markedly higher absolute collagen area in the PBD group (25,315,551 ± 21,865,238 μm 2 vs. 112,668 ± 77,844 μm 2 ; p < 0.001).

In the multivariate model for OS, RCB‐III remained an independent adverse prognostic factor (HR: 19.078, 95% CI: 4.127–88.183, p = 0.002), whereas RCB‐I and RCB‐II did not reach statistical significance. For disease‐free survival, univariate analysis showed that pCR was strongly associated with improved DFS (HR: 0.073, 95% CI: 0.028–0.187, p < 0.001).

In the contralateral eyes, with the GFAP-RA time variations, an increase in GFAP-RA was found at 5 days with respect to the rest of the times; although, it did not reach statistical significance at any of the time points except at 15 days ( p < 0.001) ( Figure 9 A).

However, the difference in severe ADEs in the FQ vs non-FQ group did not reach statistical significance; however, the overall rate of nonsevere ADEs in FQ compared with non-FQ regimens was 43.3% vs 6.1% ( P < .001).

While spearman correlations of ∆ aY with d y (rho = −0.45) and Δ Y (rho = 0.11) did not reach statistical significance, the HCE growth rate of adults Δ A showed a strong, statistically significant correlation with ∆ aY (rho = 0.81, p-value < 0.001).

Higher histology stages of 3 and 4 were associated with higher mean biomarker levels, but this difference did not reach statistical significance regarding reported history of schistosomiasis infection, telomerase levels were significantly higher among those with schistosomiasis ( p < 0.001), but no such difference was found in terms of CD44 ( p = 0.768) or NMP22 levels ( p = 0.375).

In the Usual Care group, the proportion of sites manifesting swelling decreased, but this did not reach statistical significance (APCD: 0.033 (95% CI: 0.017, 0.049), p < 0.001; UC: 0.017 (95% CI: −0.003, 0.036), p = 0.14).

Regarding the LPP, although the context-by-time interaction did not reach statistical significance in the quadratic model, simple slopes analyses indicated that the time effect remained significant in the gain context, b = −0.75, z = −3.93, P < .001, but not in the loss context, b = −0.34, z = −1.78, P = .075, a pattern consistent with the primary linear analysis.