“did not reach statistical significance”

While the OA/HA group also showed a trend toward cartilage preservation (Week 12: 6.5 ± 2.08), this did not reach statistical significance compared to the OA group at any time point. 3.3 Immunohistochemical Analysis of Cartilage Metabolism and Inflammatory Markers 3.3.1 Type II Collagen (COL II) Expression COL II expression followed a treatment‐dependent pattern throughout the study period (Figure 2 ).

Interestingly, the expression of mcBOX, a repetitive element, showed a trend towards upregulation in the H3K9M group, although the change did not reach statistical significance.

A decreasing trend in immune cell number was observed in the sample treatment groups compared to the LPS group, although this trend did not reach statistical significance ( Fig. 4A - 4D ).

Similarly, competition enzyme-linked immunosorbent assay (ELISA)-based surrogate virus neutralization tests (sVNTs) showed a trend toward lower neutralizability of the hyposmia/anosmia only subpopulation, although it did not reach statistical significance (symptomatic [respiratory and other] versus hyposmia/anosmia only, P = 0.099), possibly due to the small subset size ( n = 6) ( Fig. 3B ).

In the same group, a positive trend was also observed for visceral fat score, although this association did not reach statistical significance (B = 0.384, 95% CI -0.001 to 0.769; p = 0.051).

Conversely, as delineated in Table 4 , within the male cohort, irrespective of whether TyG Q1 or TyG Q2 served as the reference, the DR risk associated with TyG Q3 and TyG Q4 did not reach statistical significance, nor was a significant trend of increasing risk observed.

In non-obese subjects, the CT+CC group showed a trend toward higher sodium intake scores and total moderation scores compared to the TT group; however, these associations did not reach statistical significance after applying the corrected p -level for stratified analyses.

Interestingly, CRP showed a trend toward higher values in the sepsis group but this did not reach statistical significance ( p -value = 0.086).

Although the model group exhibited a numerical increasing trend in B cell frequency compared to the normal control, and the ShL group showed a corresponding downward trend, these differences did not reach statistical significance among any of the experimental groups ( p > 0.05; Figure 5 C,D).

Among sirtuin family members, SIRT1, SIRT3, and SIRT4 exhibited >2-fold induction (log 2 FC ≈ 1.0–1.3), whereas SIRT5 showed a positive trend that did not reach statistical significance, likely due to low read counts and partial RNA degradation in irradiated samples.

While the PFD and LROF groups exhibited an increasing trend, these changes did not reach statistical significance when compared to the MOD group.

During co-treatment of LPS with TMs, Cxcl10 and Il1b levels decreased in sera derived from treated mice compared to those in sera from control mice (treated with LPS+DMSO); the anti-inflammatory cytokine Il10 showed an increasing trend that did not reach statistical significance, whereas Il6 and Tnfα did not show altered levels in mouse sera ( Fig. 7 C).

WLP Improves the Gut Microbiota Dysbiosis of MASLD Rats Alpha diversity analysis reveals that the Chao, Ace, and Sobs indices exhibited an increasing trend after WLP group treatment, though the difference did not reach statistical significance ( Figure 4 A–C).

Although the RW group (the other intervention arm) showed a trend toward a greater ISWT distance compared with the UC group, the difference did not reach statistical significance (MD 38.91 m, 95% CI −10.91 to 88.74 m; P =.13).

Training duration during isolation showed a positive trend but did not reach statistical significance (β = 0.241; p = 0.051).

Although MinPf showed a numerical trend toward a between-group difference, this difference did not reach statistical significance ( Table 3 ). 3.2.

Rades et al [ 55 ] tested a simple reminder app for skin and mouth care during radiotherapy; while it did not reach statistical significance, it showed a trend toward fewer severe side effects.

5B , larvae treated with the combination of DOX and NV716 showed a trend toward increased survival compared to DOX alone; however, this difference did not reach statistical significance under the tested conditions.

Similarly, it is possible to observe a numerical trend in favor of the prepectoral position regarding the CC rate, even if the data did not reach statistical significance.

On the contrary, patients who received GDFT in the study by Bacchin et al had significantly lesser blood loss as compared with controls. 13 This difference could be due to the variable spine pathology and surgical experience of different surgeons in our study. In our study, there was a decreasing trend in the use of intraoperative fluid in the GDFT group which however did not reach statistical significance probably due to the transfusion of less volume of fluid in both groups.

While no specific Ratio of Ratios (RoR) was significantly different from 1 for any pair, certain comparisons, such as "Non opioid analgesic plus Opioid: Non opioid analgesic" (p=0.0782) and "NSAID plus Non opioid analgesic plus Opioid: Non opioid analgesic" (p=0.0759), exhibited marginal p-values, suggesting a possible trend towards inconsistency that did not reach statistical significance.

Although the expression of miR−122−5p in the UUO + no injection group showed a decreasing trend compared with the sham group, this did not reach statistical significance ( Supplementary Figure S1 ).

At the protein level, inhibition of miR-99b-5p in MDA-MB-231 cells resulted in a statistically significant upregulation of DR5 and BAK1, while BCL-XL expression exhibited a decreasing trend that did not reach statistical significance ( Figure 2D ).

The rs6427528 ( CD84 ) variant showed a trend toward benefit, but this did not reach statistical significance ( p = 0.055).

Although their study suggested a slight trend toward greater dermal and subcutaneous thickness on the subcutaneous side, these differences did not reach statistical significance, likely due to the small sample size ( n = 6).