Conversely, 30sACT showed significant negative correlations with both TMT-A (R = −0.3655, p = 0.0335) and TMT-B (R = −0.3645, p = 0.0341), while its correlation with DSST did not reach statistical significance ( p = 0.0112).
Reductions in HRV parameters (pNN50, high-frequency power, low-frequency power, and total power) remained directionally consistent with poorer autonomic function in the HMS group, although the overall models for power variables did not reach statistical significance ( p = 0.012–0.033 for group; model p ≈ 0.080).
Time-to-potency recovery analysis showed a trend favoring ultrapreservation, though this did not reach statistical significance after Bonferroni correction (log-rank test, p = 0.012).
Although this difference did not reach statistical significance ( χ 2 P = 0.012), it supports several other studies that note a general decline in female-first authorship across scientific fields in 2020 due to the COVID-19 pandemic ( 23 , 24 ).
Even though this decrease did not reach statistical significance in the whole cohort, subgroup analysis showed that the decreases were significant in patients with high VEGFR2 expression (93% vs. 67.7%, p = 0.012), or positive kinase-insert domain-containing receptor expression (94.4% vs. 47.3%, p = 0.002) [ 13 ].
Practice patterns similarly trended toward increased RA use among more experienced clinicians, although this did not reach statistical significance; conversely, reporting a lack of skill as a barrier decreased significantly with more experience (Fisher’s exact p=0.012).
However, the PVVS- QoV ( bothersome ) correlation did not reach statistical significance (r = -0.30, p = 0.012).
Vaccination status was a weaker predictor of all three outcomes than both antibody thresholds and did not reach statistical significance for the endpoint oxygen requirement (mortality aOR: 2.646, 95%CI: 1.239–5.650, p = 0.012; ICU aOR: 2.924, 95%CI: 1.368–6.252, p = 0.006).
The difference between the second and third sessions did not reach statistical significance after correction ( p = 0.012).
In the left FFA and the left pSTS, the prediction rate was greater than chance; however, it did not reach statistical significance after multiple comparison correction: left FFA (t(12) = 2.57, p = 0.012), left pSTS (t(7) = 2.54, p = 0.019).
Although LINC00662 was expressed in all tumoral and nontumoral tissues, its expression was higher in the tumor and peritumoral parenchyma than in cirrhotic CVH parenchyma, but the difference between peritumoral and CVH parenchyma did not reach statistical significance (11.87 and 11.05 fold, p=0.012 and 0.16, respectively).
General factor FA was a trend level predictor (β = 0.218, p = 0.015), but did not reach statistical significance after correction for multiple comparisons ( p < 0.0125).
However, the results did not reach statistical significance after applying the Bonferroni correction, with a significance threshold set at P < 0.0125 (0.05/4).
All four endometrial cell lines demonstrated an enrichment of endometrial cancer heritability in the anchors of promoter-associated loops ( Table 2 ), although the enrichment in Ishikawa loops did not reach statistical significance (Bonferroni threshold, p < 0.0125). 2.3.
When evaluating SES independent of race and ethnicity, there was a trend toward an association between SES and OS, although this did not reach statistical significance ( P = .0129).
However, for hip fractures, the relationship between ASYR and SDI did not reach statistical significance ( β = 16.88, R 2 = 0.03, p = 0.0131) ( Supplementary Figure S13 ).
Although the difference in TIL CD8 + T cells did not reach statistical significance, the TIL CD8 + /Tregs ratio on day 14 significantly declined compared to that on day 7 (9.005±6.422 vs 23.10±7.625; P =0.0134).
10.1136/bmjopen-2021-055392.supp1 Supplementary data Overall, there was a slight female predominance (54%) and although the proportion of male patients did not reach statistical significance in the univariable analysis, male sex was associated with a lower overall risk of relapsing disease (OR 0.16 95% CI 0.04 to 0.68; p=0.014) and time to first relapse (HR 0.46 95% CI 0.24 to 0.89; p=0.011) in multivariable analyses ( figure 1 , online supplemental table 2 ).
The predicted elevated recall for position 5 following prioritisation ( M = 0.54, SD = 0.19) compared with the control (non-prioritise) condition ( M = 0.44, SD = 0.17) did not reach statistical significance following Bonferroni correction, t (23) = 2.66, p = .014, d = 0.54.
While overall performance on healthcare responsiveness ( r = −0.34, p = .075) did not reach statistical significance (although at a borderline level), responsiveness in workplaces ( r = −0.46, p = .014), schools ( r = −0.59, p < .001), and society ( r = −0.53, p = .003) correlated with the overall status – the better the responsiveness, the worse the MH status.
Moreover, it was observed that lnc‐ITSN1‐2 ( Z = −1.852, p = 0.064) had an increasing trend in deaths compared to survivors, but did not reach statistical significance (Figure 4A ); meanwhile, the Th1 cells ( Z = −2.450, p = 0.014), Th17 cells ( Z = −2.124, p = 0.034) and IL‐17A level ( Z = −2.393, p = 0.017) were enhanced in deaths than those in survivors, but not IFN‐γ level ( Z = −1.049, p = 0.294) (Figure 4B‐E ).
Although the trend for contrast to predict OS did not reach statistical significance, PFS were longer in patients with high contrast ( P = 0.015).
The comparison between AD and non-neurologic disease controls did not reach statistical significance following multiple testing correction ( p = 0.015).
Clavien–Dindo IIIa complications were reported in 13.0% (3/23) of NOSE-LRR patients, with no events in the other two groups; this difference showed a trend but did not reach statistical significance ( p = 0.015).
In COPD subjects, a similar pattern was observed, but did not reach statistical significance ( P =0.015).