Although ε4 showed a trend toward increased risk (aOR 1.09, 95% CI: 0.46 to 2.49) and ε2 toward a protective effect (aOR 0.82, 95% CI: 0.24 to 2.36), these did not reach statistical significance after multiple testing correction (BH‐FDR‐adjusted p > 0.05) (Table 2 and Figure 2 ).
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Similarly, retinal HVA showed a trend toward preservation in the ON group (ΔHVA: − 0.12 ± 2.28 ng/g wet weight) compared to NC (− 7.09 ± 2.13 ng/g wet weight) and OFF (− 3.77 ± 2.62 ng/g wet weight), but this did not reach statistical significance (ON vs.
Length of hospital stay showed a trend toward prolongation in infected patients, although this did not reach statistical significance ( P = .085).
The difference between Group 1 and Group 2 showed a trend but did not reach statistical significance after correction ( p = 0.065).
Baseline mSASSS showed a trend toward association but did not reach statistical significance (OR 1.09 per unit increase, 95% CI 0.99–1.20, p = 0.078).
While the other comparisons did not reach statistical significance, they all exhibited a decreasing trend.
a strong trendgold
At this time point, the 177 Lu-PSMA617 + genistein group exhibited a 78.1% reduction in tumor volume compared to 177 Lu-PSMA617 monotherapy, while the 177 Lu-PSMA617 + baicalein group showed a 50.2% reduction, demonstrating a strong trend of enhanced efficacy, although these differences did not reach statistical significance ( P > 0.05) (Fig. 4 B).
Although ESTIMATEScore also showed an increasing trend, the difference did not reach statistical significance ( Fig. 3 F).
While near total and subtotal resections showed a trend toward higher recurrence risk, these did not reach statistical significance.
Compared with the control brains, PSD95 intensity in STZ brains showed a decreasing trend at 3 days, while VGLUT1 intensity showed a decreasing trend at intact, 3 days, and 14 days post-injury; however, these differences did not reach statistical significance (SFig. 3 ).
WT Mtb showed a trend towards decreased heme levels under iron limitation compared to control media, and a further reduction in total heme with the addition of NO stress, although this did not reach statistical significance ( Fig 6A ).
At the final follow-up, patients with Ki-67 ≥ 15% displayed a numerical trend toward a higher rate of structural incomplete response, though this did not reach statistical significance ( p = 0.123).
Intraoperative hypotension showed a trend toward a higher incidence in the in-hours group, although this did not reach statistical significance (31.6% vs. 20.0%, p = 0.054).
For the primary outcome of 90-day mRS 0–2, compared with SoC, rt-PA significantly increased the proportion of functionally independent patients (RR = 1.21, 95% CI 1.06–1.38, low certainty), JX10 (RR = 1.50, 95% CI 0.87–2.58, very low certainty) and TNK (RR = 1.07, 95% CI 0.93–1.23, low certainty) showed a trend toward improvement but did not reach statistical significance.
The DAB-positive area did not reach statistical significance, though TNBC samples showed a numerical trend toward higher values compared with HER2+ and Luminal tumors (Fig. 3 ).
BPQD@Fer-1 showed a trend toward longer median survival than free Fer-1 treatment, although the difference between these two groups did not reach statistical significance in the log-rank test ( Fig. 6 C).
Diabetes mellitus showed a trend toward increased risk but did not reach statistical significance after adjustment (adjusted odds ratio 2.05; 95% CI 0.96–4.37; p = 0.064) ( Table 4 ). 3.3.
a positive trendgold
Physical activity also showed a positive trend across legume consumption groups (p for trend = 0.019), although differences did not reach statistical significance (p = 0.062).
Although the improvement in social novelty (In Stage 2) did not reach statistical significance, there was an increasing trend in interaction time with Stranger 2 (Fig.
Finally, it should be emphasized that, although a slight trend toward lower-frequency displacement shown by some features is observable between the Normal and Moderate groups, these differences did not reach statistical significance (Bonferroni-corrected ), indicating that the spectral shift becomes substantial only from Moderate to Severe.
Kellgren–Lawrence grade showed a trend toward higher odds of lympho-myeloid infiltration (OR 1.54, 95% CI 0.96–2.51) but did not reach statistical significance ( p = 0.074).
Epidermal thickness showed a trend toward increase but did not reach statistical significance (P = 0.063, Figure 6 F).
Statistical analysis showed a trend toward higher PD-L1 positivity in ERO1A-high patients, although this did not reach statistical significance ( P = 0.074; Fig. 6H ).
Peripheral neuropathy showed a trend toward reduced odds of major amputation, although this association did not reach statistical significance (p = .098).
a positive trendgold
The correlation between the ALPS-mean and MoCA scores showed a positive trend, although it did not reach statistical significance (r = 0.186, p = 0.058).