Barely Significant
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“did not reach statistical significance”

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Although ε4 showed a trend toward increased risk (aOR 1.09, 95% CI: 0.46 to 2.49) and ε2 toward a protective effect (aOR 0.82, 95% CI: 0.24 to 2.36), these did not reach statistical significance after multiple testing correction (BH‐FDR‐adjusted p > 0.05) (Table 2 and Figure 2 ).
did not reach statistical significanceP > 0.051.0× alphaplainly factual
At this time point, the 177 Lu-PSMA617 + genistein group exhibited a 78.1% reduction in tumor volume compared to 177 Lu-PSMA617 monotherapy, while the 177 Lu-PSMA617 + baicalein group showed a 50.2% reduction, demonstrating a strong trend of enhanced efficacy, although these differences did not reach statistical significance ( P > 0.05) (Fig. 4 B).
For the primary outcome of 90-day mRS 0–2, compared with SoC, rt-PA significantly increased the proportion of functionally independent patients (RR = 1.21, 95% CI 1.06–1.38, low certainty), JX10 (RR = 1.50, 95% CI 0.87–2.58, very low certainty) and TNK (RR = 1.07, 95% CI 0.93–1.23, low certainty) showed a trend toward improvement but did not reach statistical significance.
did not reach statistical significancep = 0.0641.3× alphaplainly factual
Diabetes mellitus showed a trend toward increased risk but did not reach statistical significance after adjustment (adjusted odds ratio 2.05; 95% CI 0.96–4.37; p = 0.064) ( Table 4 ). 3.3.
Finally, it should be emphasized that, although a slight trend toward lower-frequency displacement shown by some features is observable between the Normal and Moderate groups, these differences did not reach statistical significance (Bonferroni-corrected ), indicating that the spectral shift becomes substantial only from Moderate to Severe.