Barely Significant
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“did not reach statistical significance”

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Validation Analysis In a meta-analysis of 3 independent data sources, rs738409 G showed a trend for association with a reduced risk of COVID-19 hospitalization/severe disease vs mild disease; but the result did not reach statistical significance (additive OR: 0.83; 95% CI, 0.66–1.05; P = .12; P heterogeneity = .68) (see Figure 1 ).
did not reach statistical significanceP = 0.061.2× alphaplainly factual
When evaluated as a continuous variable, number of MBD ED encounters pre- vs post-enrollment showed a favorable trend for the intervention but did not reach statistical significance (OR = −0.24, P = 0.06 for the combined study results).
LTCF3 exhibited a significantly lower rate of urinary tract infections compared to LTCF1 (IRR = 2.12; 95% CI: 1.14–3.94; p = 0.004), and also showed a trend toward lower rates of conjunctivitis and COVID-19, although these differences did not reach statistical significance—Table 2 .
did not reach statistical significancep = 0.153.0× alphaplainly factual
There was also an increasing trend in left ventricular internal diameter during diastole (LVIDd) from 36.2 ± 2.8 mm prior to infarction to 38.7 ± 2.9 mm and 40.9 ± 5.4 mm following infarction and at 8-weeks respectively (Figure 3 b), though this parameter did not reach statistical significance (p = 0.15).
did not reach statistical significancep = 0.2865.7× alphaplainly factual
Baseline LDH levels showed a numerical trend toward higher values in dogs that subsequently developed PD (median 748 U/L; range: 612–921 U/L) compared to those achieving CR (median 612 U/L; range: 398–846 U/L), although this difference did not reach statistical significance ( p = 0.286, Kruskal–Wallis test), likely due to limited sample size. 3.7.
However, the findings regarding improvement rates reveal an interesting trend, with a higher percentage of patients in the control group showing improvement compared to the medication group, although the difference did not reach statistical significance.