The association between pCR rates and the (predicted) prognostic groups did not quite reach statistical significance (χ 2 = 10.3076 on 5 degrees of freedom; p = 0.067).
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“did not quite reach statistical significance”
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p=0.063
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Eleven patients (8.2%) had long-term Densiron 68 retention, while failure was seen in 24 patients (17.9%) There was a trend for higher final reattachment rate after Densiron 68 removal for recurrent RRD (68 eyes (79.1%)) compared with those who had primary RRD (31 eyes (64.6%)) although this did not quite reach statistical significance ( table 3 ; p=0.067).
A similar trend was observed with respect to the risk of relapse; however, it did not quite reach statistical significance ( P = 0.067).
Diplotype 2 (AGAG/AAAA, 2748 ng/mL) had a higher median than the others, although the difference between it and diplotype 3 did not quite reach statistical significance ( p = 0.067).
By this metric we detected only a weak positive correlation between MYCN expression and copy number that did not quite reach statistical significance (ILMN_1653761: rho = 0.23, p = 0.0672; ILMN_2219767: rho = 0.24, p = 0.0522).
Visceral expression of Pparg ( Figure 5 b) and Cebpa ( Figure 5 c) were approximately 50% lower in the exercise group, although these did not quite reach statistical significance ( p = 0.0674 and p = 0.1058 respectively).
TPOAb positivity showed a similar trend with higher mortality (35.5% vs 26.5%) and an adjusted OR of 1.74, but this did not quite reach statistical significance (95% CI 0.96-3.14, p=0.068).
Percent distance travelled in the centre of the arena was also lower in Dao −/− than Dao +/+ mice, although this trend did not quite reach statistical significance ( F 1,34 = 3.524, P = 0.069).
34 In the LevoRep study, assignment to levosimendan was associated with a 50% lower risk of death, heart transplant, or acute HF compared with placebo, but this difference did not quite reach statistical significance (HR 0.50, 95% CI 0.24–1.025; P = 0.069). 21 It is important to highlight that in our study, repetitive levosimendan administration was safe and well tolerated: the adverse events rate was comparable between the levosimendan and placebo groups, including a similar incidence of patients with an adverse event leading to discontinuation of the therapy.
a strong trendgold
We observed a strong trend toward reduced tau pathology in the contralateral hippocampus of DMR7- and SKT82-treated mice compared to their respective IgG1 and IgG2b controls, although this did not quite reach statistical significance using two-tailed unpaired Student’s t-tests ( p = 0.069 and 0.077, respectively).
The patients taking statins appeared to have a better performance status and were more often treated with chemotherapy while on ICB, although these results did not quite reach statistical significance ( p = 0.069 and 0.067, respectively).
There was no significant interaction between NLR and LVEF category (<40% or ≥40%) for the association with the primary outcome ( P = 0.06) or mortality ( P = 0.27), with NLR significantly associated with the primary outcome in patients with LVEF < 40% (HR 1.24; 95% CI 1.12–1.35, P < 0.001), though the association did not quite reach statistical significance in patients with LVEF ≥40% (HR 1.10; 95% CI 0.99–1.23, P = 0.07).
Similarly, in a sensitivity analysis restricted to patients with biopsy proven KS only, patients with three or more chemotherapy indications had a 2.12 (95% CI 0.93–4.86, Model 1) times risk of rapid chemotherapy initiation, though this did not quite reach statistical significance due to the smaller sample size of patients that had biopsy-proven disease ( p = 0.07).
After the program, the prevalence of metabolic syndrome seemed to decrease to only 22%, which did not quite reach statistical significance ( p = 0.07).
PD-1 expression on CD4+ T cells was somewhat higher than in controls, but did not quite reach statistical significance ( P = 0.07).
Their group also noted a shorter hospital stay (from 30 to 18 days) after instituting CPD nebulization, but this did not quite reach statistical significance ( p = 0.07) [ 11 ].
There was also evidence that those with constipation were more likely to use a footstool or other toileting aids, although this difference did not quite reach statistical significance ( P = 0.07).
Mitochondrial density appeared lower bilaterally in the etanercept-treated animals ( Figure 7e ), but the difference did not quite reach statistical significance ( P =0.07).
The LCAT and PON1 activity of low pH-treated HDL was also reduced compared to their respective control, though the difference in PON1 activity did not quite reach statistical significance ( p = 0.07).
qPCR measurements at this timepoint confirms increased expression of these vascular genes ( Figure 2B ), although kdrl did not quite reach statistical significance ( p = 0.07).
The pattern of differences in GAD 67 levels was similar in the CP, though these differences did not quite reach statistical significance: main effect of prenatal treatment (F(1, 34)=3.492, P =0.07); diet × prenatal treatment (F(1, 34)=3.556, P =0.068).
There was some evidence for downregulation of AVP mRNA in BPA-exposed females, but the effect did not quite reach statistical significance ( p ≤ 0.07), and no effect on OT, AVP1aR, OTR, or Mc4R expression was observed in either sex ( unpublished observations ).
However, reductions in Bax mRNA associated with microbead-injection in IL-6−/− did not quite reach statistical significance (p=0.07; Figure 5C ).
As illustrated in Figure 1b , a statistically significant decrease in HMGB1 was found in OA cell nuclei when compared with normal ( P < 0.03), and, although there was more positive staining in the extra-nuclear (cytoplasm and in the cell vicinity) compartment, this did not quite reach statistical significance ( P < 0.07).
However, there was slight evidence that a larger tumour was associated with a lower chance of a success, but this result did not quite reach statistical significance ( p = 0.07).