Patients receiving CDK4/6i also had a longer OS in multivariate analysis but this did not quite reach statistical significance (HR 0.41, 95%CI 0.16–1.03, p = 0.062), although PS ≥ 2 was significantly predictive of shorter OS (HR 2.39, 95%CI 1.13–5.03, p = 0.021).
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“did not quite reach statistical significance”
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p=0.063
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The significant association of two copies of SE and failing the first non-biological DMARD with starting biological therapy previously observed in cohort 2 did not quite reach statistical significance in the RA population (respectively, p=0.062 and p=0.051).
In the top panel the effect of maraviroc on diminishing arrest for the CCR6 +(high) CCR2 - cells did not quite reach statistical significance ( p = 0.063), whereas the p value was 0.0312 when samples were analyzed specifically for the arrest step using the arrested/rolling cell ratio (bottom panel).
Those in the poor adherence group also scored higher on the internalizing problems scale, but the difference did not quite reach statistical significance ( p = 0.063; unpaired t test) (Table 3 ).
This SNP was not significantly associated with risk of early onset PD (p = 0.480), and this association did not quite reach statistical significance in the combined early and late groups (p = 0.063).
In agreement with these results, miR-34-5p was decreased by enoxacin in both the sequencing data and the RT-PCR validation, although the latter did not quite reach statistical significance (P value = 0.0635, Fig.
Additionally, there was a significant association between a greater difference between total fluid intake and urine output at 24 hours and a longer LOS in multivariable analysis ( P = 0.048) that did not quite reach statistical significance in single-variable analysis ( P = 0.064). 4.
However, that difference did not quite reach statistical significance ( p -value = 0.064), as presented in Table 2 .
A greater proportion of patients in the historical cohort (15.4%, n = 25) were commenced on supplemental therapy of any description compared with the app-assisted group (8.92%, n = 15) however this did not quite reach statistical significance ( p = 0.064).
The difference approximated but did not quite reach statistical significance ( p = 0.064).
The score also improved IDI significantly (change in IDI = 0.0149, p<0.0001), but the improvement in C-index did not quite reach statistical significance (p = 0.064) ( Fig. 2a ).
Regarding overall trends in functional limitations, in men there was a slight increase in odds over the about two decades, whereas in women the small decrease in odds did not quite reach statistical significance ( P = .064).
A similar trend was found in U-251MG; however, TRAM-34′s effect in NSC medium did not quite reach statistical significance (see Figure 9 B,C; p = 0.0649).
Overall, the yearly incidence of cellulitis reduced from a mean ± SD of 0.92 ± 1.34 per year before treatment to 0.46 ± 0.81 per year after treatment; however, the reduction did not quite reach statistical significance ( P = .065; Figure 5 ).
Associations of maternal serum PAPP-A concentrations at week 15 with the subsequent development of gestational hypertension did not quite reach statistical significance in the number of participants studied [OR 0.613 (0.365, 1.030), P = 0.065, McFadden’s pseudo r 2 = 2.1%, n = 361].
Similar to disease-free survival, the highest levels of iNOS showed a trend towards increased metastasis but did not quite reach statistical significance (p=0.065).
Significant age-adjusted linear decreases in BMI (p = 0.0091), WC (p = 0.0003) and GLUC (p < 0.0001) with increasing PAI were found, while the age-adjusted linear trend for LDL-C did not quite reach statistical significance (p = 0.0650).
This was not just because of the greater numbers with zero BrAC before the legislative change: Those with a BrAC above zero at entry to NEDs tended to have lower levels before the new legislation compared to the sample after the legislative change, although this did not quite reach statistical significance ( F (1,967) = 3.42, p = .065; See Fig 3 ).
In our study, we also observed that, for patients with stage III/IV disease, the mOS and 5-year survival rate of those receiving radiotherapy were 96 months and 80.0%, respectively, which were more favorable compared with those of patients not receiving radiotherapy (12 months and 30.3%, respectively), although this difference did not quite reach statistical significance with the number of investigated patients (P=0.0656).
During the 6 months after the supervised treadmill exercise intervention had been completed, between 6‐ and 12‐month follow‐up, the WIQ distance score declined in the treadmill exercise group compared with the control group, but the difference did not quite reach statistical significance (−8.8, 95%CI −18.3 to +0.6, P =0.066) (Table 4 ).
Fellows (PGY-4 and beyond) also had a lower rate of reported burnout compared to residents, although this difference did not quite reach statistical significance (33% vs 41.6% respectively, p = 0.066).
ET-1 correlated with log albuminuria, r = 0.407, but did not quite reach statistical significance at P = 0.066.
a clear trendgold
There was a clear trend towards an increased outgrowth when supplementing NGF with BDNF and NT-3 (3x cocktail) although it did not quite reach statistical significance ( p = 0.066).
This reflects the differing directions of associations between regions though the difference between groups did not quite reach statistical significance (Breslow-Day test of homogeneity p = 0.066).
As in the previous experiment, we found significant right-biased expression of Cckar + neurons ( Figure 4O ; percent Cckar + , left, 11.86% ± 0.91%; right, 19.60% ± 1.83%; p = 0.0162; paired t test), but differential expression of Chrna3 + did not quite reach statistical significance ( Figure 4P ; left, 19.97% ± 2.28%; right, 24.77% ± 2.51%; p = 0.0661; paired t test).