“close to significance”

In order to better validate the generalizability and stability of our method, we relaxed the selection criterion of p-value to "close to significance" when selecting instrumental variables.

However, it is important to highlight that the interaction related to LRP1 came close to significance ( p -value of 0.057).

The p -values close to significance thresholds may reflect underlying trends, but firm conclusions cannot be drawn at this stage.

Among at least 16 different GWASs on drug response since the first was published in late 2007, less than half have shown genome-wide significance, although some potentially interesting associations that come close to significance have been detected in several of the studies in this category. 15 Altogether, these reports suggest that conventionally corrected P -values for the combined samples are not the only criteria to find true associations between SNPs and the phenotypes examined.

Even when confronting angry individuals with neutral ones, the meta-analysis found an overall effect size only close to significance – but with an opposite (i.e., positive) effect of anger on information processing ( McKasy, 2020 ).

The results of the analysis demonstrated that only ethnicity ( p < 0.05) within a section of knowledge was significant, while sex ( p = 0.05) was close to significance.

The results of the permutation test for the GSTZ1 gene came close to significance, but without actually meeting the threshold ( Figure 1 B).

However, the HR for 28-day mortality was close to significance among the SOFA-adjusted population (HR 0.59) [ 52 ].

Correlations between sGFAP and BMI (r = −0.157, p = 0.055), sNfL and BV (r = −0.157, p = 0.055), and sNfL and body weight (r = −0.145, p = 0.079) were close to significance, but their p values remained >0.05 (eTable 2, links.lww.com/NXI/A751 ).

However, in participants not exposed to CRT, the relative risk for pre-hypertension and hypertension was close to significance (RR = 1.93, 95% CI 0.96–3.88).

With a larger sample, other personality traits might have been highlighted, especially considering that some traits were close to significance in our study.

In the multivariate analysis, we considered variables such as obesity, hypertension, surgery, and sex, which, although they did not reach statistical significance, had p -values close to significance and are relevant in our clinical context.

Indeed, a p -value close to significance was obtained.

SCC R is related to locomotor behaviours Independent of geomean (a proxy for body size), the SCC radius of curvature ( R ) is not significantly correlated with locomotion in the PGLS in both regression formulas ( R ~ geomean + locomotion, and R ~ geomean × locomotion); however, both regressions have p ‐values close to significance (Table 1 ; Figure 3 ).

The reduction in mean travel time after propensity score matching was consistent with greater access to care among phone owners and was close to significance, -2.6 hours of travel time to healthcare (95%CI: -5.5–0.3) (Tables I and J and Figure E in S1 Text ).

An additional group of 8 had P values close to significance at 0.05 to 0.08.

SUV peak presented no statistical significance with a P -value of 0.058, which was close to significance.

English as the primary language at home (OR = 2.00, 95% CI = 0.99, 4.02, p = 0.052) and living arrangements (OR = 1.90, 95% CI = 0.93, 3.86, p = 0.077) were close to significance.

A single 25-Gy radioablation dose was delivered by a linear accelerator-based volumetric modulated arc therapy technique to a mean clinical target volume of 39 mL over 31 min; the reduction in recurrent VT burden was significant at 3 months and close to significance at 6 months, with the limitation of the sample size.

Regarding the relationship between oocyte number and metals: Fe ( r s =0.303; p =0.003) and Ca ( r s = −0.276; p = 0.007) were significant and Al ( r s =−0.195; p = 0.061) and Na ( r s = −0.174; p = 0.095) were close to significance.

Although neither the effect of INA ( B = + 2.905, [−0.075, +6.953) nor that of H/I ( B = + 0.233, [−3.034, +2.876]) was statistically significant, the INA score was close to significance and accounted for a considerably larger portion of the total effect (54.1% vs. 4.3%).

While some subfields, such as the right CA2CA3 or left subiculum, showed at least a trend, others were not even close to significance, providing strong evidence for spatial specificity.

In keeping with this, the lower hazards of liver fibrosis/cirrhosis in class 3 were not significant and class 4 (persistent high viraemia) is close to significance after adjustment for the relevant confounders.

Falls were significantly more frequent during winter and close to significance in those greater than 65 years of age during winter in this study.

49 We also observed weaker activation in the occipital ROI compared with NH, a similar mechanism as seen during visual speech; however, it was only close to significance in the statistical analysis.