After FDR correction, only the positive correlation between lignin intake and serum ALT levels in children from the Prevotella enterotype remained significant (P FDR < 0.05), while the correlations between hemicellulose intake and insulin resistance markers were close to significance (P FDR < 0.2; Supplementary Table S5 ).
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The latter model also detected a strong evidence of positive selection in the gene categories “virulence, detoxification, adaptation” and “lipid metabolism ( p = 0.00027 and 0.000, respectively), while values close to significance resulted from the site model for the gene categories “conserved hypothetical proteins” and “virulence, detoxification, adaptation.” Consistent with LRT results, BEB analysis under the site model further identified nine putative positively selected sites, seven of which map to the gene category “cell wall and cell processes” with a posterior probability >95% ( Table 1 ).
in group E ( p = 0.0765) were close to significance as well.
We found that the number of TILs before (but not after) NACT was a significant prognostic marker of 3yr-OS, an association that persisted (close to significance) even when the pCR group was considered independently (data not shown).
In linear mixed models adjusted for kinship, age, sex, and APOE genotype, the variants located in SLC9A3R1 (rs41282067), ITIH2 (rs143731868), and RHBDD2 (rs190871206) remained significantly associated with LOAD ( p ≤ 0.005 adjusted for multiple testing, table 2 ), and the variant in CDH23 (rs56013867) was close to significance.
With the exception of models that included intestinal cestodes, all revealed positive slopes that were either significant or close to significance, but none explained more than 3.1% of variance.
The fertility rates seemed to be higher in Chaoborus treatment only at later ages (interaction of treatment with age), but the effect was only close to significance ( figure 1 c and table 3 ).
Of the remaining 12 studies, only one showed no improvement, four reported P ‐values close to significance, and seven demonstrated statistically significant improvements.
The indirect effect of body weight on RI% ret 1H via dROMS was negative and close to significance ( Table 3 B, Supplementary ), suggesting a potential mediation pattern.
At age 11 (Literacy stage) these significant differences disappeared in all tasks, except for in RANa/n and a close to significance in Sentence comprehension, However, when using one‐tailed t‐test significance was reached (p < .05), and Cohen's d ranged in the four age tests from .54 to 0.69.
We should mention that in this study, sarcopenia has shown associations close to significance with events such as disability or mortality.
Risk factor levels of systolic blood pressure, serum cholesterol, and smoking habits were significantly higher in NE than in SE, while BMI was so in SE versus NE, and no significant difference was found for age and heart rate (although the latter close to significance).
P values under 0.05 were considered significant (* p < 0.05, ** p < 0.01, *** p < 0.001), though values close to significance were also indicated, as the small group sizes limit the chance of reaching statistical significance.
No other differences were close to significance.
Despite a significant increase of total haemoglobin mass (THM) of ∼7% on average and red blood cell volume (VRBC) 8,5% no correlation was found between the changes V RBC in and the concurrent changes in V̇O 2max ,which increased close to significance in case of V̇O 2max (6.9%).
The second a priori interaction contrast was non-significant [ t (26) = 2.03, p > 0.05 eta-squared = 0.07, effect-size = medium, power = 0.60, expected N to detect a significant difference with a power of 0.80 = 120], although the effect size was close to significance.
The only difference on the CEBQ between the intervention and control groups which came close to significance was for Emotional over-eating.
Only variables with a significant p-value or close to significance were included in the regression model and a p-value less than 0.05 was considered statistically significant.
This was, however, not reflected in the statistical analysis (i.e., no significant Group effects, and none of the interactions involving Group coming even close to significance).
gait speed, all of which were close to significance).
At 2 μg/mL, although the difference was not statistically significant (p ∼ 0.052), the result was close to significance, suggesting that inhibitory effects might begin to manifest at this concentration.
Although we do not find any significant differences between the two groups in the moderator analyses, several of the estimates for the highest-functioning half of the sample are relatively high and close to significance compared to the lowest-functioning half, where the estimates are close to zero.
Heterogeneity was not detected between cut-off value ≤3 and cut-off value >3 groups (P=0.051), although the P-value was close to significance, and the pooled HRs were 1.22 (95% CI, 1.08-1.38) and 1.58 (95% CI, 1.26-1.98), respectively.
The percentage of power in the alpha range was close to significance but did not pass the correction for multiple comparisons ( Table 1 ).
Transforming growth factor-alpha, IL18R1 were close to significance, possibly due to the small sample size (Fig. 1 B).