However due to some polymorphisms being close to significance more study into this area and a larger data pool would help to provide increased certainty into any possible role including greater insight into specific MMR gene mutation subtypes to discern whether the minor role still holds true.
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“close to significance”
In the literature
Interestingly, while not statistically significant, IL22 gene that plays a critical role in modulating tissue responses during inflammation [GO:0005125, GO:0006954], was found to be close to significance with increased expression in the birds treated with the VA2013 isolate (padj cut-off value = 0.07).
In mouse, the depletion results were close to significance, and we noticed numerous nervous system structures present at the top of the list ( supplementary table S10 , Supplementary Material online).
However, the association between higher BASDAI score and lower omega-3 PUFA consumption was close to significance.
Mirroring the previous results of observed differences, bootstrapped ratios of within to between-subject variability were not significantly different for the α parameter ( F boot = 1.05, 95% CI = [0.55, 1.98]); we find a difference that was close to significance for β ( F boot = 0.59, 95% CI = [0.31, 1.05]) and a significant difference for σ ( F boot = 0.38, 95% CI = [0.22, 0.64]).
SS provided a higher Odds ratio close to significance (OR = 3.47; p ˃ 0.05; CI 1–11.9) ( Figure S1C ). 3.8.
We found that age and systolic blood pressure were significantly associated with CIMT, while gamma-tocopherol was close to significance ( Table 4 ). 3.2.
In both Tyro3- and Axl-knockout mixed glial cells, Gas6 was no longer able to alter IL-10 expression, whereas in Mer-knockout cells, Gas6-induced IL-10 upregulation was observed to be at about the same level as in wildtype cells, close to significance ( Figure 3 C).
We wanted to include in the multivariate analysis variables that were close to significance and that we deemed clinically relevant (such as age and accidental removal of parathyroid tissue).
Labor type and episiotomy rates were also similar across both groups, though induced labor ( P =.083) and unknown episiotomy status ( P =.076) were close to significance.
Only the coping strategy “problem-focussed avoidance” came close to significance regarding PI and PU.
Gastrocnemius medialis showed results close to significance.
However, unlike existing literature, our study did not reveal a significant association between postgraduate rural placements and practising in rural areas but, the results were close to significance.
When our analysis is limited to data from aortic regions, we reached the same conclusion about r ec modification ( p < 0.02) and this effect is not significant for the thoracic region ( p < 0.065) but close to significance.
Age was close to significance with a trend towards more antibiotic prescriptions in older patients.
There were no significant correlations or correlations close to significance ( Table 3 ).
Significant differences between groups were observed for concentration impairment: 5.5% (4.1% to 6.9%) versus 2.4% (1.3% to 3.5%) and differences close to significance were observed for skin rashes: 4.5% (3.3% to 5.8%) versus 2.4% (1.3% to 3.5%), and sore throat/pharyngeal inflammation: 2.9% (1.8% to 3.9%) versus 1.5% (0.6% to 2.4%).
However, it should be noted that the direct correlation between the incidence of endometrial cancer and the density by 90 Sr contamination (ρ = 0.34, p = 0.06) is close to significance.
However, the HR for severe flares with cCR vs DORIS 2021 Remission was close to significance ( P -value of 0.052), and therefore larger studies would be useful to assess if a statistically meaningful difference can be detected.
1,67-5,62) than in Europe; the diagnosis of NIID was more frequent in Middle East and Far East Asia than Southern Asia, the risk of having a NIID in Europe vs Southern Asia was close to significance (OR 4.17; IC 0.95–18.41); the diagnosis of neoplasm was more frequent in the case-series from Southern Asia and Middle East vs those from Far East Asia and Europe.
Comparison of FA Implants With Standard of Therapy In the present network meta-analysis, FA implants tend to be more effective in long-term, targeted control of inflammation as compared with SOC, and the difference is close to significance, which caused fewer side effects of cataracts and elevated IOP ( Figures 2C,E,F ).
However, some other variables were close to significance also (Table C in S1 File ).
Although we observed that only reintubation, age, hypercapnia at the end of the SBT and obesity were significantly associated to mortality, time to reintubation was close to significance, maybe influenced by a low statistical power due to a reduce sample size.
But to be mentioned here is that male participants were non-significantly more likely to be blood donors (OR: 1.43 [95% CI: 1.00; 2.06]) with a close to significance p -value of 0.051.
However, because the p -value was close to significance it is important to note that this trend for an interaction is in the opposite direction to that found in Experiment 1.