A further complex matter concerns the effects of sex on HPA functioning, within the above mentioned associations; different sex patterns were reported to be close to significance only in women ( DeSoto and Salinas, 2015 ; Puig-Perez et al., 2016 ), whereas the absence of sex differences occured after controlling the luteal phase ( Kajantie and Phillips, 2006 ; Poppelaars et al., 2019 ).
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For fine wrinkle, compared with the placebo group, adapalene was associated with an odds ratio (OR) of 9.29 (95% CI [0.95, 90.92], P = 0.0554), indicating an effect that was close to significance but not statistically significant.
Symptom severity, treatment length (i.e., days until evaluation) and treatment option were found as significant, while endoscopic findings were close to significance (Supplementary Table S6 ).
Where the difference is close to significance, the actual p value is noted.
The QG group had a p -value close to significance at 0.0626, suggesting potential publication bias, and a high Tau 2 of 98.304 indicating substantial heterogeneity.
Finally, although, strictly speaking, the relationship did not reach statistical significance, we did find an association close to significance between the response to an LABD and performing exercise.
Further, the only variables that did not reach significance or close to significance when adjusting for age and sex were total cholesterol, LDL, LDL/HDL ratio and diabetes.
In EnCa, although the association between STC expression and RFS outcomes did not reach statistical significance (HR 0.59, 95% CI 0.35-1.02, P = .055), the findings were close to significance, suggesting potential prognostic implications for EnCa, with lower STC1 expression associated with shorter RFS time ( Fig. 3C ).
The faster 16.1 km TT in the slower group was determined by a higher average power and speed profile across the whole TT, being close to significance at 8 km and different at 12 km with no difference for the faster group.
The variables, which were found to be significant or close to significance by univariate analysis, were evaluated by Cox regression analysis.
Regarding retired women, only subjects aged less than 70 years with D ≥ 3 had a significant risk for psychotropic drug use (that would be due to manual workers who had a higher consumption, close to significance).
Item (12) User’s (youth’s/parent’s) own assessment of risk was close to significance.
Only the time between the peak and the end of the wave presented P -values close to significance.
= 5.96, p = 0.052) were close to significance.
Close to significance are two associations, one between the marker rs3131296 in NOTCH4 (chromosome 6) and prodromal onset (developmental readout), the other between rs12807809 in chromosome 11 (near NRGN gene) and severity of the neurological signs ( Table 2 ).
In males, the interaction between genotype and treatment at PPI 5 was close to significance, but this interaction was not significant at PPI 10 or 20 [PPI 5: F (1, 34) = 3.487, p = 0.070; PPI 10: F (1, 34) = 0.027, p = 0.871; PPI 20: F (1, 34) = 2.655, p = 0.112].
Interestingly, although the significant variables of the control and intervention group did not match, in the backward gait measured with the force plate, all corresponding variables in the respective other group were close to significance (significant before Bonferroni correction, p -values between 0.013 and 0.028).
Discussion Our study demonstrates hyperuricemia as an independent risk factor for NAFLD in elderly populations (adjusted OR 2.165, 95% CI 1.277–3.669, p = 0.00413), with particularly pronounced effects in individuals with concomitant hypertriglyceridemia (TG ≥ 2.26 mmol/L: OR 7.07, 95% CI 1.72–29.18, p = 0.0002), Although the interaction P-value of 0.0857 did not reach the conventional significance threshold (p < 0.05), it was close to significance.
The NLR in women was also positively correlated, but the correlation was slightly weaker, with an OR of 1.04 (95% CI 1.01-1.09) and a P value of 0.031 for Model 3, and an OR of 1.67 (P=0.053) for quartile IV, which was close to significance.
Among individual comorbidity groups, cardiovascular diseases showed a significant positive association, while neurological and mental health conditions were close to significance (Supplementary Data 1 ).
However, it is important to mention that these findings should be interpreted with caution, due to type 1 error, and only the correlations with testosterone reactivity are close to significance.
This linear relationship was also close to significance at the intergenotype level (Fig. 3 b), suggesting a possible genetic trade‐off.
Also interaction between C-HR and exclusion was significant and 3-way interaction of C-HR, Ego-depletion and exclusion was close to significance.
automated insulin delivery carbohydrate counting precision medicine type 1 diabetes Clinical Research Department of the Sud‐Francilien Hospital Subgroup analysis showed consistent results across subgroups of patient baseline characteristics, albeit overall interaction was close to significance for sex, age and baseline daily dose of insulin (overall p interaction of 0.16, 0.16 and 0.15 respectively).
At this point, we could find differences close to significance in total body bioluminescence, emitted by luciferase-expressing cancer cells, between mice treated with T22-PE24-H6 and buffer-treated mice ( Figure 6B ).