We further validated this potential causal relationship using SomaScan pQTLs 47 (Methods), where the weighted median estimator 48 showed significant result (OR = 0.89, 95% CI: 0.81-0.98, p -value = 0.019) while the IVW estimator was close to significance with the same direction of effect (OR = 0.94, 95% CI: 0.87–1.02, p -value = 0.12).
However, the difference between groups YY and YN is only close to significance according to the regression results ( p = 0.12; Figure 5 ).
ABCB5-KD melanoma cells by a factor of three, two and two (respectively), whereas relative alanine and aspartate increases by about 15% were close to significance (0.05 < p ≤ 0.12; % of totH and totP, Tables 1 and 2 ).
The MR-Egger regression estimate showed close to significance and converging results as IVW estimate and WM estimate (OR MR–Egger = 1.68, 95% CI: [0.87, 3.27], p = 1.23 × 10 –1 ).
They also had more embolic phenomena in general, which was close to significance at p = 0.1268.
When we added dummy variables representing each parent’s education level (Table 2 , Model 2), which may proxy socioeconomic status and cultural values, only one coefficient estimate was close to significance (mother has A-levels or higher, female equation, positive sign, p = 0.127).
Lepidoptera increased significantly in abundance (Lepidoptera: treatment 1.0 ± 0.5 SE , control −0.5 ± 0.3 SE , N = 15, paired t test p = .01), and Coleoptera showed a large increase that was close to significance (treatment 1.3 ± 0.9 SE, control −0.3 ± 0.4 SE , p = .13).
In A2780 cell line statistically significant decreased expression of PTPRK was observed after 24 h, 48 h and 72 h incubation ( p < 0.05), with the exception of 10 ng/mL after 48 h incubation where downregulation was close to significance ( p = 0.13) ( Figure 4 B). 2.5.
Since these SNPs were close to significance, the haplotype was considered, but even combined together, they were not correlated with the grade of side effect ( p = 0.13).
Robust paired t -tests (Yuen’s bootstrapped) showed no significant increased HbO concentration in V-STI with respect to non-STI in any phase (only the left R2 difference was close to significance, p = 0.13) ( Figure 2 and Table 2 ). 3.3.
72.6% ± 10.8% in the ER group with close to significance ( p = 0.134, Figure 2 ).
However, among these power outcomes, LE relative power was close to significance (P = 0.14) with a small ES = 0.33 (-0.81, 1.47) and the ES for LP relative power was moderate-large (0.78 (-5.0, 2.07)).
pH did not appear to be a significant factor affecting enucleation; however, pairwise comparison showed the difference between pH 7.3 and 7.5 to be close to significance ( p = 0.14); this is in agreement with the advantage to elevated pH reported previously and our observation of the persistence of non‐CD235a expressing cells at pH 7.3 (data not shown).
Δ age is not correlated with chronological age (Δ age Hannum, r=-0.07, p=0.47; Δ age Horvath, r=0.009, p=0.92), on the other hand it is correlated to stroke status with Hannum Δ age (r=0.24, p=0.008) and close to significance with Horvath Δ age (r=0.133 p=0.143).
For the multivariable analysis, we considered those variables whose p -values were significant or close to significance ( p ≤ 0.15) in the univariable analysis.
Predictors of Postoperative PVR and Visual Outcome Variables that were significantly different between the RRD group and the PVR group or were close to significance in univariate tests ( P <0.15) were selected for stepwise logistic regression analysis.
Variables that achieved significance ( P < 0.05) or those that were close to significance ( P < 0.15) by the log-rank test were subsequently included in the multivariate analysis using a forward stepwise Cox regression model for the analysis of factors associated with OS, with adjustments for confounding factors.
Interestingly, at baseline the prediction of caloric intake from the magnitude of liking ratings of the most preferred pudding sampled during session 1 was close to significance and stronger in the at risk SBPp patients (r = 0.38, p = 0.16, Fig 5B right ) than in SBPr patients (r = - 0.14, p = 0.53, Fig 5B middle ).
No other marginal or interactive effects involving monthly amount gambled or gambling severity were close to significance (minimum p = 0.16).
While this might indicate that including a second killing rate does not improve the models for these conditions, P values were close to significance ( P = 0.1641 and 0.1074, respectively) and various test statistics (Akaike information criterion [AIC], Bayesian information criterion [BIC], and log likelihood [LogLik]) were either inconclusive or in favor of the biphasic model (Table S2).
At follow-up, ANCOVA analysis was close to significance ( P = 0.17) within the rACC and post hoc analysis showed increased left δ-fc-NAc in the rACC in the SBPp patients compared to SBPr ( P < 0.05, whole brain corrected) ( Fig. 2 D ).
On stratifying by weight status, the association of PC2-Z with serum TG and GGT was nominally significant, and remained close to significance after FDR correction in all groups ( P < 0.17), except for underweight children (Supplemental Table 6 ).
CRP levels in the ASS HbSS group showed a negative correlation with disease severity scores with P value being close to significance ( P = 0.17) [ Figure 2 ] WBC also showed a negative correlation with CRP levels in the same group of subjects ( P = 0.73), [ Figure 3 ].
The 2-fold increase in average serum corticosterone in the male offspring of chromium-treated fathers may have tended to increase IGF BP1 synthesis; correlation between corticosterone and IGF BP1 mRNA levels was close to significance for these animals (p = 0.19; data not shown).
Although none of the interactions was close to significance (all F < 1.50, p > .192), indicating congruency in all contingency conditions, we again tested our predictions for the different contingency types by separately assessing congruency effects.