The new results of the SNC-study were quite comparable with the findings reported in the WHO evidence review: small increases in risk were often found, which were, depending on adjustment for confounders, borderline significant.
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A borderline significant association was observed after excluding the Shanghai Women’s Health Study and Shanghai Men’s Health Study (RR = 0.90, 95% CI 0.82–1.00; Supplementary Table 5 ).
As the sample gets larger, the variability of even borderline significant confounders gets smaller, and they get retained as significant variables, hence diminishing the retention differences between the selection methods.
There was a borderline significant association between prenatal aspirin use and placental eGAA among the overall population (β: + 0.35 weeks gestation; 95% CI: − 0.01, 0.72) (Fig. 3 ).
However, we found a borderline significant association between cannabis use and overall ASCVD development when we combined the observational studies assessing cannabis and CAD and IS individually with observational studies assessing cannabis and mortality or incident ASCVD.
We have amended the result to show 3 decimal places and to state that it is only borderline significant: “For “outcome expectations”, those aged 60-75 seemed more likely to have low motivations as compared to those aged 40-59, with borderline significance (adjusted OR 1.569, 95% CI 1.004-2.453, p=0.048).” We have also removed the outcome expectations from the discussion section given the marginally significant result.
By contrast, the borderline significant associations disappeared in this reverse comparison, and also when we limited our analysis from Figure 5b to a distance cutoff of 25 kb.
This association remained borderline significant in the multivariate analysis using the additive model.
Vaccine type was also included in the top statistical models ( Appendix Table 1) and the trend toward reduced odds of Omicron infection after vaccination with the Janssen vaccine was borderline significant (OR 0.351, 95% CI 0.132–0.935, relative to Pfizer vaccine; OR 0.388, 95% CI 0.149–1.009, relative to any mRNA vaccine) ( Table 2 ).
The SNP rs1533484 was borderline significant (Bayesian significance ∼0.06) and demonstrates consistent effects with the NECS and SICS results, but the allele frequencies are substantially different.
As the ABCG2 c.34G > A SNV showed only a borderline significant association without correction for multiple testing and has shown an opposite association with rosuvastatin pharmacokinetics in a previous study, 32 it was excluded from further analyses. 3.3.
However, differences were not statistically significant for Whites vs Hispanics (RR 1.02, 95%CI: 0.94-1.11), and borderline significant for Whites vs Blacks (RR = 1.10, 95%CI: 1.00-1.22)[ 8 ].
The results were borderline significant—frequency of graft rejection was lower in patients with the CC genotype (CC vs.
There was a borderline significant association between higher sedentary time and risk of pregnancy-induced hypertension and/or preeclampsia (OR 1.21, 95% CI 1.00–1.50).
Two factors that were borderline significant were the Bristol stool scale (p adj = 0.08) and age (p adj = 0.08).
This was also observed in the subgroup of type II tumours, with significant and borderline significant differences between numbers of gains and losses in BRCA2 and BRCA1 tumours, respectively ( Figure 2D ; Supplementary Table S3 ).
The borderline significant association of lower protein C levels with nonsurvivors continues to support the role for disordered coagulation in ALI/ARDS.
Untargeted metabolic fingerprinting OPLS-DA models based on patient’s aganglionic segment length showed only borderline significant validation parameter values with average prediction abilities 28 .
There were borderline significant improvements in role-physical, bodily pain, and physical health component score.
Similarly, symptom reporting did not align with exposure status, except for the same volunteer, whose symptom reporting showed a borderline significant result with exposure status.
Across the thousand different orders, the effect of pain-related disability stabilized with the fewest number of participants while the effect of sex, which was borderline significant in the full sample, stabilized extremely late.
Among the aspects of teaching experience, formulating a differential diagnosis, interpreting tests, and developing a treatment plan were significantly associated with clinic type, while selecting tests had a borderline significant association with clinic type.
While the strength of this association was relatively weak (only borderline significant at the 10% level) among all partnerships involving 16–24 year old women–indicating the need for further research to tests this relationship–concurrency was identified as a particularly strong risk factor associated with age-disparate partnerships among adolescent (16 to 19 year old) women.
It should be kept in mind though that this does not mean that vitamin D supplementation would lower the incidence of the above-mentioned pregnancy complications; published trials on supplementation have been of low quality and have only demonstrated none to borderline significant changes in outcome (De-Regil et al., 2012; Thorne-Lyman et al., 2012).
In univariable regression models, stroke was significantly associated with reduced HUI-derived utility weights; borderline significant associations were seen with diabetes and marital status (Additional file 1 ; Table S1).