“borderline significance”

NPM1, IDH2 R172 , and TP53 mutations are predictive of survival in elderly AML patients Clinical factors significantly predictive for poor OS in univariate Cox analysis in intensively treated patients were male gender, high lactate dehydrogenase, poor WHO performance status, and high ELN risk, while low hemoglobin and AHD–AML showed borderline significance ( P -values 0.08 and 0.06, respectively) (Supplementary Table S3 ).

In statistical testing, a two-sided p value ≤0.05 was considered statistically significant, and 0.05 < p ≤ 0.10 was regarded as a marginal or borderline significance.

12 , 15 Even though our risk estimate was of only borderline significance, it was consistently about 1.7 and reached statistical significance in several subanalyses (eg, when we adjusted for other autoimmune thyroid disease and when we used age instead of time since CD diagnosis as the time scale).

Additionally, a second hypermethylated CpG cg22336863 with β > 0.045 was found upstream of the transcription start site of actin‐binding Rho‐activating protein ( ABRA ), with an FDR‐adjusted p ‐value of 0.068, indicating a borderline significance that might reach statistical significance with a larger sample size (Table 2 ; Table S2 ; Figure S3 ).

Given its borderline significance and genomic proximity to significant sites, CpG7 was retained alongside CpG6 and CpG8 for subsequent analyses.

Although no statistically significant finding was observed, the result indicates a borderline significance.

NAC at higher dose 20 mg/mL reduced the levels of IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, GM-CSF, INFγ, TNFα (all p = 0.035 to 0.002) with IL-1α ( p = 0.051) at borderline significance.

Besides, men with liver cancer were more probable to have lower body mass index and be non-regular exercisers compared with controls, although the difference was at borderline significance.

Although the total number of fractures was reduced by 43% (35–50%) during the pandemic, we found that the proportion hand fractures was lower (significant), the proportion of femur fractures was higher (borderline significance), whereas the proportion of fractures at other locations was relatively constant.

In addition, salvia reduced TGF-β serum levels in rats (decrease in IL-6 and TNF-α levels were with borderline significance).

While the CC and CT genotypes were in higher frequency in the 3 rd stage (40% and 50%) and in 4 th stage (36% and 54%) than controls (31% and 46%, respectively) with borderline significance.

Energy adjusted MUFA and proliferation were associated, albeit with borderline significance.

They found, with borderline significance, that patients with anemia tended to have a higher mean HbA1c level than did patients without anemia.

negative protein expression) with a borderline significance.

With regard to NSVT, our study showed TPG had borderline significance at rest and significance at stress.

Otherwise, cognitive-behavioral therapy (CBT) and mindfulness-based intervention showed borderline significance compared to the psychoeducational intervention (SMD, −0.18; 95% CI, −0.36 to −0.00) ( Figure 2 a).

However, that study reported an association between childhood trauma and lower net scores under risk, which is partly suggested by the borderline significance observed among males in relation to ELS in our current study.

In agreement with our results, 22:6ChE was reported to be increased in forebrains of mutated APP/presenilin-1 mice (11-fold, p < 0.01) and mutated APP mice (3-fold, borderline significance), but not of presenilin-1 mice (0.9-fold) at 9–11.5 months of ages, compared with wild-type mice [ 9 ].

A multivariate regression analysis, adjusted for prognostic co-variates including age, sex, heart disease, diabetes mellitus, pulmonary disease, tumors, hypertension, and dyslipidemia, confirmed this result (HR 0.27, CI 95% 0.06–1.19, p = 0.085), albeit with borderline significance, possibly influenced by a small sample size effect (Fig. 3 ).

Currently smoking had borderline significance.

Similarly, 3 previous meta-analyses reported that berry supplements, anthocyanins, or polyphenols (the latter 2 not limited to berry origin) reduced HbA1c by 0.20–0.53% ( 16 – 18 ), although with borderline significance in 1 of the meta-analyses ( 16 ).

Additional adjustment for circulating insulin levels in the final multivariable model attenuated the results to borderline significance (1.95 [0.87–4.40], P -trend = 0.078).

Two biomarkers (MCPP, MCNP) exhibited elevated RRRs for Non-TD risk with borderline significance (i.e., their lower confidence bounds were 0.95 and 0.96, respectively).

In agreement with our results, the IL-1RN *2 genotype has been proposed to be associated with reduced breast cancer prevalence, and the IL1RN 2 allele was found to decrease the risk of breast cancer with a borderline significance 18 .

In the univariate analysis using logistic regression, factors significantly associated with cure on the first visit were age [OR=0.97 (95%CI 0.94-0.99)], being unmarried [OR=2.20 (95%CI 1.14-4.23)], etiological diagnosis of gonorrhea [OR=2.18 (95%CI 1.10-4.43)], etiological diagnosis of non-gonococcal urethritis [OR=0.45 (95%CI 0.24-0.85)], and more than 8 years of schooling [OR=1.91 (95%CI 0.99-3.67)], which had a borderline significance ( Table 2 ).