Barely Significant
← all phrases

“borderline significance”

7,018 sentences · 7,018 papers · 11,572 search hits before verification

In the literature

In a similar way, assessments and cross-comparison of NOS isoforms in animals of different age groups with and without exposure to acute SD showed considerable age-dependent decrease but only in nNOS (the bilateral drops to 48.8% and 41.6%) and eNOS activity (the significant drop to 58.7% in the L side, that with borderline significance to 65.1% in the R side), with the activity levels of iNOS remaining stable across different age groups ( Figure 5 A–C).
Regarding preoperative diastolic LV parameters, there was a statistically significant difference between the two groups only in the left atrial volume index (LAVI) and a borderline significance in the average diastolic mitral annulus velocity (e’ average). 3.3.
No SNVs in the MASP1 gene region were significantly associated with MASP-3 serum levels after multiple testing correction; however, two intronic SNVs in high LD were associated with higher MASP-3 levels with borderline significance (top hit rs78008995) ( figure 4C,D , analysis stratified for disease status is shown in online supplemental figure 3 ). rs78008995 did not have a strong effect on MAP-1 serum levels (p value unadjusted 0.085, adjusted p=1.0).
In the ABCSG R02 trial we previously demonstrated that downstaging of the N-level and particularly the achievement of lymph node negativity after neoadjuvant RCT with capecitabine and oxaliplatin (ABCSG R02-Study) exerts a statistically significant influence on 5-year OS and DFS in this patient population ( 23 ), whereas downstaging at the T-level showed no statistically significant influence on OS and only a borderline significance in DFS.
The primary significance threshold was set at FDR < 0.10 based on the following considerations: (1) EFEMP1 (plasma-pQTL OR = 7.96, 95% CI [2.17–29.21]) exhibited borderline significance (FDR = 0.062) under conventional FDR < 0.05 [ 39 ]; (2) Its extreme effect size (OR > 5.0) satisfied our tiered confidence criteria for moderate signals [ 40 , 41 ]; (3) Field standards support FDR < 0.1 for novel biomarker discovery in proteomics [ 42 ]; (4) Empirical validation showed 0% false positive rate at FDR < 0.1 in the negative control analysis.