In addition, ECOG PS ( P = 0.096) and IPI score ( P = 0.061) had only borderline significance (Table 1 ).
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“borderline significance”
In the literature
Some borderline significance occurred in our study, such as BMI and ApoB (Tables 1 and 2 ), possibly because of these limitations. 5.
Furthermore, the borderline significance of the correlation between β 2 M RR in HDF mode and sieving coefficient values measured under the same conditions could be explained by factors relating to the patient.
With borderline significance, the total MET-min/wk measured by the questionnaire was higher in men than in women, but the total MET-min/wk measured by the accelerometer was higher in women than in men.
Furthermore, pre-NACT nuclear Trx expression was associated with the prolonged DFS, but only with borderline significance.
The evaluation of publication bias did not reveal significant asymmetry (Egger’s test: p = 0.090; Table 7 g), though borderline significance warrants cautious interpretation given substantial heterogeneity.
The highest LDL-C TTR quartile was associated with a 25 % reduction in MACE (HR: 0.75, 95 % CI: 0.68 to 0.83), 42 % reduction in myocardial infarction (HR: 0.58, 95 % CI: 0.49 to 0.68), 24 % reduction in stroke (HR: 0.76, 95 % CI: 0.64 to 0.91), and 13 % reduction in CVD death (HR: 0.87, 95 % CI: 0.76 to 1.00; borderline significance).
Although there was no significant difference in BCA and ACA between patients with and without a family history of diabetes, in the DM group islet density was significantly decreased and mean islet size was increased with borderline significance in patients with a family history compared with those without ( Figure 4 ).
This finding may indicate a potential modulatory role of ABCB1 in intracellular drug exposure; however, given the borderline significance and sample size, this association should be viewed as preliminary and requires further validation.
Additionally, the borderline significance of some variables, such as the molecular study of DNA damage and apoptosis, suggests that our sample size of rats might have been insufficient to achieve the necessary statistical power for detecting significance, especially when applying the correction for multiple comparisons.
PRS percentiles were higher in FD than in the moderate-to-low PRS group (ΔMe 8, 95% CI: 0−15; p = 0.048), with borderline significance.
However, these findings were limited to the males within the cohort, albeit of only borderline significance for birth weight; with no significant associations seen in females.
A statistically significantly higher expression of the SNAI1 gene was also observed in the endometriosis group; however, this difference was at the borderline significance.
The mechanism underlying the observed differences in visuospatial functioning among TREM2 variant carriers with AD remains unclear and warrants further research, especially considering the complex interplay of brain regions and networks involved in visuospatial functioning [ 68 ] and the borderline significance of the FDR-corrected p-value.
The effect of eHealth use on health-promoting behaviors became non-significant with borderline significance probability when health self-efficacy was introduced as a mediator.
In addition, the association between H2RA use and stroke remained significant before and after matching, whereas the association between PPI use and stroke appeared less stable, showing borderline significance.
However, vildagliptin was suggested to have a lower risk of CV disease with borderline significance (OR 0.82, 95% CI 0.68 to 0.99), which is consistent with the results from pooled data of 25 phase 3 trials assessing cardio-cerebrovascular safety of vildagliptin [ 26 ].
Previously, four lncRNAs ( H19 , HOTAIR , HULC and MALAT1 ) were reported to be associated with HCC, but only HOTAIR was borderline significance ( Table 2 ) in the current study.
Similar results were achieved for DFS in PAAD Data-2, while borderline significance was noted for DSS in PAAD Data-1 ( Supplementary Figure S2E ).
When restricting to patients admitted from the community, results remained similar, though only borderline significance was found in the primary model for the younger age group (HR: 1.30, 95% CI: 0.95, 1.79) ( eTable 9 ).
The association of serum LDH above the upper normal limit with HPD had borderline significance supported by only two studies.
Although this is a secondary outcome and the borderline significance of the P value found, a tendency toward a positive association with our presumption is appreciated.
Nevertheless, serine serum levels showed borderline significance for OS in univariate analysis and serine has a widely accepted role in cancer cell metabolism.
With a larger sample, codes that demonstrate borderline significance will likely have adequate power.
In addition, if six datasets measure a gene as significantly differentially expressed, and six show only borderline significance, which set is ‘right’?