Furthermore, we found a borderline relation between reduced SEVR and diabetes: diabetic and IFG patients had lower SEVR (although with borderline significance) as compared to normoglycemic subjects.
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In the literature
The same meta-analysis also identified HLA-DRB1*12 : 02 (protective signal #3 in Fig 1 ) as TB protective marker with borderline significance [ 41 ].
Disease stage ( P = 0.145) and tumor histology ( P = 0.174) had only borderline significance (Table 4 ).
3 However, the recommendations were based on small-size randomised controlled trials (RCTs) with borderline significance or uncontrolled open-label studies. 3 To our knowledge, this is the first prospective study to investigate the efficacy and safety of baricitinib in refractory TAK patients.
6 Previous meta-analysis suggested that hematologic malignancies were more likely to occur in patients with IBD, but the result showed borderline significance. 7 For specific types of hematologic malignancies, the results of research vary and deserve further analysis and exploration. 8 In addition, with the development of research, the therapeutic agents of IBD have changed, and more and more biologics have been adopted.
Our effect estimates and CIs borderline significance, which may limit the clinical relevance of our findings; however, our findings may have implications for public health given that a high proportion of US women in our study gained weight outside of the range recommended by the IOM and a large number of women entered pregnancy overweight or obese.
Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres.
In males, Cox2 showed significant differences between saline-exposed and LPS-exposed groups in all AA/SBO groups, except the AA/SBO 0.37 group that showed borderline significance ( Fig 8 , right panels; S2A Fig ).
An additional limitation relates to the relatively small sample size of the thermochemotherapy group, which may have reduced statistical power and contributed to the borderline significance observed in multivariable analyses.
This would account for factors such as percentage of missing data in each study arm, the ratio of missing data to event rate for each study arm (ie, the higher the ratio, the larger the change), fragility of statistical significance (ie, borderline significance), the magnitude of the effect estimate (ie, the larger the effect estimate, the smaller the change), and the duration of follow-up (ie, the longer the duration of follow-up, the higher the percentage of missing data).
Hypertension showed a hazard ratio (HR) of 1.319 (95% CI: 0.973–1.789), suggesting a 31.9% increased hazard of stroke, though the CI crosses 1.0, indicating borderline significance.
However, after employing a 1:1 nearest propensity matching analysis, the studied variant showed only borderline significance with asthma under the dominant model in 71 matched cohorts.
However, the p -value reached only a borderline significance after Bonferroni correction for the multiple testing.
In patients without T2DM, testosterone inversely correlated with NT-proBNP, showed no significant correlation with LVDD or the NYHA class, and showed a borderline significance with the duration of HF ( Table 3 ).
The GG genotype of ADORA1 rs2228079 was found significantly more frequently in patients with OCD/OCB, depression and, at borderline significance, with non-OCD anxiety disorder.
The coexpression of CD39 and Ki67 appeared specifically associated with T-Ag–specific T cells at all time points, with borderline significance at week 12 ( Figure 4E ).
In multivariate CR analysis, only correlation of low CD3+ TIL with DFS or OS remained significant ( p < 0.001, Table 5 ), while low PD-L1 showed borderline significance with OS.
4 b). Comparisons of the number of embryos available for transfer in DOR women according to clinical pregnancy and live birth As the number of surplus embryos showed borderline significance, we further performed analyses on the number of embryos available for transfer (embryos that were transferred plus those that were frozen) according to clinical pregnancy and live birth.
Our data suggested that the AST/ALT ratio and MCV had borderline significance in predicting hazardous drinking.
A marked increase in NLR levels was particularly observed in the proliferative stage, while PLR demonstrated borderline significance.
The intended positive association of the policy with progression is found for Class C miscellaneous offenses, though the effect is small and at a borderline significance level.
In sensitivity analysis ( Table S1 ), when Cox proportional hazards regression analyses were performed for 69,516 participants, including workers whose group of working hours had changed during the follow-up period, the association between weekly working more than 52 h at baseline and incident glucose intolerance, compared with working 35–40 h, was still observed with borderline significance in Model 3. 4.
In the fully adjusted model, the point estimates for CMM risk in the highest quartile were higher than those in the lowest quartile for all indices; except for RFM, which showed borderline significance, the differences for the remaining indices were statistically significant.
However, for the stratum-specific estimates, there was an attenuation of the association between education and mortality in the intrapair analyses in all strata but males born during 1921–1935 for whom the association was actually slightly stronger and displayed borderline significance (HR = 1.25, 95% CI: 0.99, 1.57 compared with HR = 1.17, 95% CI: 1.06, 1.30).
Similar findings were noted for the risk of Alzheimer’s disease, whereas the association between glucose variability and incident vascular dementia showed borderline significance.