Additionally, although multiple Doppler parameters were compared in this study, no correction for multiple comparisons was applied, which may increase the risk of Type I error, particularly for findings with borderline significance. Therefore, findings with borderline statistical significance should be considered exploratory and hypothesis-generating.
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“borderline significance”
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Hence, the borderline significance was set between 0.05 and p values < i/46.
Although the PERMANOVA analysis revealed borderline significance between the downloaded periodontitis datasets, they were pooled to detect potential taxonomic differences between our samples and the periodontitis samples.
As a consequence, our findings may ignore certain previously identified POAG-associated genes, especially those with borderline significance or lack of intersection evidence.
SUVmaxpre was also able to predict local recurrence, however with borderline significance.
[ 11 ] that showed increased risk of CVE with aromatase inhibitor compared to placebo with borderline significance.
In addition, we identified SNPs in genes with genome-wide significance (including those with borderline significance, i.e.
Additionally, this only had borderline significance in other studies [ 44 ].
Again, there was no longer any significant heterogeneity ( I 2 = 0%, P = 0.44) after removing the study by Jian and the pooled RR changed to 0.977 (95% CI 0.951–1.003, P = 0.080) with borderline significance for all studies.
In multivariate analysis, the ERCC1 19442C > A genotype was an independent predictor for TTP with borderline significance after adjustment for ECOG performance status, sex, and number of organs with metastases (adjusted HR for patients carrying C/C compared with patients carrying A/A genotype as a reference, was 2.365 (95% CI, 0.909–6.155; P =0.078) ( Table 4 ).
LiSN-S scores differed more from control values numerically in those who reported auditory dysfunction, but such reached only borderline significance compared with scores in those without complaints, suggesting that the auditory dysfunction in FRDA is incompletely captured by LiSN-S testing.
Furthermore, HOMA-IR at baseline increased per 1.0 reduced the risk of relapse by 14.6% with borderline significance, and every 1 mmol/L increment of PPG after CSII increased relapse risk by 15.6% ( Table 3 ).
In contrast, the average S&S matrix scores for de novo 3′ ss were not significantly higher than corresponding mutated sites and were not lower than corresponding authentic 3′ ss, except for a borderline significance of intronic de novo 3′ ss ( Table 1 ).
Meta-analysis of these two studies revealed that the addition of radiotherapy was associated with improved 5-year survival, with borderline significance (odds ratio: 2.26, 95% confidence interval: 0.9–5.71, I 2 =27%) ( Figure 2 ).
At 12 months of age, the Sci-B-Vac group had lower HBsAg carriage rates (1/89, 1.1%) than the Engerix-B group (5/82, 6.1%) with borderline significance (risk difference of −0.05, 95% CI −0.11–0.007, t -test = 0.05), and borderline significance lower vaccine failure rates with anti-HBs < 10 mIU/mL in the Sci-B-Vac (2/89, 2.2%) than in the Engerix-B (8/82, 9.8%, p = 0.05).
Stratifying the meta-analysis by study design resulted in an increased OR estimate of the association between PM 2.5 and glaucoma to borderline significance for cross-sectional studies, but moderate heterogeneity was still measured.
Also, age and body mass index were shown as predictors with borderline significance, whereas CRP, FFAs and triglyceride were not.
BVAB 3 reaching borderline significance in the latter.
In multivariable analysis, conditioning intensity and ferritin remained significant, with donor type showing borderline significance.
In contrast to the warm period, where no obvious association was observed, an IQR (10 μg.m −3 ) increase in lag0 of PM 10 tended to increase AMI hospitalisations by 2% in the cold period, with borderline significance.
Season and sun exposure remained significant predictors, while smoking retained borderline significance and parity lost statistical strength.
Already after 4 weeks of diabetes, a time-point when no changes in aortic plaque size had yet occurred, expression of VCAM-1, MCP-1, IL-1β, Cox2, TF and maybe also IL-6 and ICAM-1 (borderline significance) were higher than in control non-diabetic mice.
For several of the other atherosclerotic characteristics including CAC score, the associations did not remain significant, although the associations for coronary diameter stenosis ≥ 50% (OR 1.17, 95% CI 0.99–1.37, P = 0.060) and severe coronary atherosclerosis (OR 1.29, 95% CI 0.99–1.66, P = 0.051) showed borderline significance for the highest tertile of hsCRP compared to the reference (Table 3 , Fig. 1 b).
PSMA-TLQ measurement differences gave a borderline significance with a p -value of exactly 0.05.
CT-guided ROI method had higher AUCs than manual SPECT method with borderline significance.