The observed borderline significance association with the use of any OC is in line with what expected (Collaborative Group on Hormonal Factors in Breast Cancer, 1996).
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“borderline significance”
In the literature
Second, the age difference reached only borderline significance, whereas the creatinine level was significantly higher for the lower 27 patients.
In the present study with patients with a mean BMI of 26.0 kg/m 2 , a high BMI showed borderline significance as an independent risk factor for aborted EGD.
Additionally, although the IL-18 rs187238 polymorphism is associated with sepsis prognosis, its modest effect size and borderline significance suggest that further research is needed to confirm its clinical relevance as a reliable prognostic marker.
BMD of the femoral neck decreased in both study groups after 2 years, although to a lesser extent with MK-7 supplementation and with borderline significance between treatments groups.
Finally, based on PFS, we filtered and arranged 29 targets with inclusion criteria: (1) response AUC ≥ 0.6 and PFS ≤ 0.05 in both TR and ET cohorts ( AKT1S1 , NSL1 , ESRRA , TMEM81 , CKB , SGEF ); (2) statistical significance in PFS/OS of two cohorts ( KRT19 ); (3) borderline significance between CR and PD ( SCG5 , CEACAM1 , ALOX12B ) and seven targets with inclusion criteria; (4) statistical significance in PFS of TR or ET cohort.
Unfortunately, in our patient cohort of stage IVB patients, only narcotics at the time of diagnosis was statistically significant; histology, visceral versus nodal metastases, age, race, language, and size of cervical mass were not statistically significant factors, and anticoagulation at time of diagnosis was only had borderline significance.
For recurrence-free survival, the HR for positive cross-match results for B cells at 37°C was 2.58 (95% CI: 0.98-6.78; borderline significance) and that for positive cross-match results for T cells at 4°C was 3.35 (95% CI: 1.08-10.40).
At the gene level, we identified six (four with borderline significance) susceptibility CS-related genes, including FCN1 , which is expressed in leukocytes and involved in elastin-binding 21 , 22 ; PLAT converts plasminogen into plasmin, crucial in cell migration and tissue remodeling/degradation 23 ; CD46 protects host cells from complement self-cell damage 24 , 25 ; F2RL2 is key in thrombosis 26 ; VTN promotes cell adhesion 27 and inhibits the MAC 28 ; and A2M , which works as a protease inhibitor 29 , 30 .
Nine studies reported that a worse dental status was associated with cognitive decline ([ 22 , 25 , 27 – 29 , 32 , 33 ], one study showed a borderline significance of the association [ 31 ]), three studies reported no significant association [ 24 , 26 , 30 ], and one reported a negative association, i.e., more missing teeth was associated with a lower risk of dementia [ 21 ].
NGT arm trial of multicenter randomized controlled FOOD trial studied the effect of the route of the enteral tube and timing on outcomes and found that early PEG in a week of stroke was associated with an increased borderline significance of the absolute risk of death [ 23 ].
Analysis stratified for ER status showed borderline significance.
In their study, the correlation between hepcidin concentrations and serum IL-6 levels showed borderline significance.
In the overweight ENSA subgroup, maternal influence on type 2 diabetes risk appeared to be larger compared with paternal effects with borderline significance (odds ratio [OR] 2.16 [95% CI 1.85–2.52 compared with 1.30 [1.02–1.67].
pAkt and other variables in relation to distant recurrence-free survival In univariate analysis neither HRG nor Akt-1 had prognostic value, while pAkt positivity predicted a higher risk of developing metastasis with borderline significance (RR=2.4, 95% CI, 1.0–6.2) (see Figure 2A ).
Only a history of previous ischaemic heart disease had a HR that was statistically significant (HR 3.0 P = 0.027) although increasing age (HR 1.5 per 10-year increase, P = 0.060) and RBBB morphology of VT induced at EPS (HR 2.6, P = 0.051) showed borderline significance.
In addition, smoking was entered in the model due to clinical relevance and borderline significance in univariate mode.
Interestingly, AKI was associated with brain injury, and postnatal hypotension tended to be associated with brain injury with borderline significance.
The number of “mini size” dogs in our sample was quite small (less than 3% of the sample population), which might explain the borderline significance.
Statistical significance was notably affected by study removal, with p -values ranging from 0.10 to 0.15, suggesting borderline significance and limited robustness of findings for this outcome.
In statistical testing, a 2-sided P ≤ .05 was considered statistically significant, and .05 < P ≤ .10 was regarded as marginal or borderline significance.
Certainly by increasing the sample size the statistical power increases and some risk factors with borderline significance might turn out to become significant.
Panel (B), Low-Busyness Group: In males with Low Busyness, survival curves for High and Low Stage remain moderately overlapping, and the p -value (0.06) suggests borderline significance.
Therefore, the results for individual cancer types, particularly those with borderline significance, should be interpreted with caution and require validation in future, hypothesis-confirming studies.
Only for young adult RNAi treatment, the 10% rescue effect on ADR-induced life-span extension reaches borderline significance (Supplementary Table 2).