Most recently, in a study of 88 cases out of a cohort of 5519 ( Swerdlow et al , 2001 ), borderline significance was found for MOPP chemotherapy compared to other treatment regimens.
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“borderline significance”
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Unexpectedly, the frequency of induced IL-10 + B cells correlated positively with FT 3 and FT 4 levels (the latter borderline significance), within the GD patients.
Four of them were significantly associated with the shape of the curves, while a fifth polymorphism showed borderline significance.
Also, as in previous studies, it is difficult to isolate the effect of smoking cessation alone, since smoking cessation was also associated with other characteristics that were of prognostic importance such as age, the type of index event, and (at a borderline significance level) previous vascular events.
This showed that reassortment rate was still significantly negatively correlated with d N /d S independent of the proportion of wild birds as host in all six internal segments (R: -0.79 to −0.44, P < 0.01; Additional file 2 : Table S3 column 5 and 7); and independently positively correlated with proportion of wild birds as host (R:-0.66 to −0.29, P < 0.07; Additional file 2 : Table S3 column 8 and 10) with borderline significance, thus both host and selective constraint are associated with reassortment rate.
Of note, the association between stage C of heart failure and degree of metabolic syndrome showed borderline significance.
While the CIs for some quartile groups widened and the P values approached borderline significance, the overall trend was consistent with the primary analysis.
Also, educational level (p = 0.05, OR = 1.4) had a risk factor effect on positive FGR (Borderline Significance).
As sipC shows borderline significance in our proteomic analysis ( Fig. 6 E ), we performed ELISA analysis for sipC to directly measure its abundances in lysozyme-treated versus untreated Salmonella supernatants.
Considering a borderline significance and the small number of studies evaluating HbA1c, further investigations may reveal a trend and help test new hypotheses about the effects of cocoa consumption on glucose metabolism.
Twenty-six out of 98 patients reached the end point during follow-up and baseline creatinine showed a borderline significance ( 4 ).
In the previous meta-analyses, Matuscheck et al was not able to record any improvement in OS and Lu et al was able to observe an improvement trend, though it had borderline significance [ 2 ] .
However, when applying FDR correction for multiple testing, only galactinol (OR = 0.56; 95% CI: 0.40–0.78; p = 0.001; FDR = 0.075) and Pyrogallol (OR = 0.50; 95% CI: 0.32–0.77; p = 0.002; FDR = 0.104) retained borderline significance. All other metabolites lost statistical significance after FDR adjustment (FDR > 0.20).
Instead, GO terms ‘DNA or RNA binding’, p FDR = 1.97E–3; ‘unknown molecular function’, P FDR = 1.97E–3; ‘transferase activity’, P FDR = 2.6E–3; ‘transporter activity’, P FDR = 3.1E–3; ‘nucleic acid binding’, P FDR = 1.2E–2; ‘other binding’, P FDR = 1.2E–2, were obtained at borderline significance levels.
Notably our permutation test showed the same tendency towards over-representation of haplogroup HV* in Seph patients with nephropathy (Table 4 ) with borderline significance (see Additional file 1 – Table 1).
The characteristic of our cohort is likely to have influenced on the result of our univariable analysis on DFS, indicating an inferior DFS in the RNI group compared to that in the no-RNI group, albeit with a borderline significance.
In the validation study [ 13 ], microarray data showed that high PITX2 methylation was significantly associated with early recurrence after prostatectomy in univariate analysis, and remained significant also in multivariate analysis together with Gleason score, tumor stage, and surgical margin status, whereas pre-operative PSA showed borderline significance.
When combined, the use of ECVS seems to be associated with better outcome (91% versus 82% of patients free from syncope recurrence), but with a p-value of a borderline significance.
T max was lower after M2SH intake compared to after HEM intake with a borderline significance.
RC comparison, the association of this data set with canonical pathways showed only borderline significance.
In leave-one-out sensitivity analyses, there was a borderline significance when Jensen et al.
L-SPN, 12 [18.75%]; P = 0.002), although abdominal infection exhibited borderline significance (H-SPN, 4 [6.25%] vs.
The albumin level on POD 3 was lower in the AL group with borderline significance (see Table 4 ). 4.
However, in the MedHi continuous analysis, only HDL-C maintained a robust association after full adjustment, with BP showing borderline significance.
Although this P -value slightly exceeds the conventional significance threshold ( P < .05), it approaches borderline significance, suggesting a possible trend toward small-study effects or publication bias.