“borderline significance”

Finally, because of the direction of the interactions, borderline significance, and relatively few nonobese diabetic participants, we cannot exclude the possibility that these interactions are due to chance.

However, a borderline significance was reported between the SNP rs11724635 and sporadic PD under the co-dominant and additive models.

Conversely, the certainty of evidence for systemic zinc administration was rated as low, having been downgraded for both imprecision (borderline significance with wide confidence intervals) and inconsistency ( I 2 = 37%). 4.

For CBVD visits, the effect of PM 10 on non-burning days was attenuated to borderline significance (1.017 [95% CI: 0.999 to 1.035]), but there was little difference to the relationship on burning days (0.998 [95% CI: 0.981 to 1.014]).

In this study, previously reported risk factors such as CRP/Alb and tumor thrombosis of IVC showed statistical significance or borderline significance (Tables 2 and 3 ) with univariate analysis [ 6 , 7 ]; and distant metastasis, a parameter reflecting tumor stage, showed to be an independent risk factor for OS with multivariate analysis.

However, it did not reproduce the significance previously found for the lower-dose group, which could partly be explained by a borderline significance in the first trial. 25 An extension to this trial shows ongoing significant reduction of MRI activity favoring the 0.6 mg/day dosage. 26 Two ongoing Phase III trials (ALLEGRO [Assessment of Oral Laquinimod in Preventing Progression of MS] and BRAVO [Benefit–Risk Assessment of Avonex ® and Laquinimod]) will provide further data and hopefully show ongoing favorable safety data.

These results had borderline significance for the existence of a dose effect.

There was evidence that carrier status for MTRR Ser175Leu is associated with a poorer prognosis (HR=1.14; 95% CI: 0.92–1.41) albeit borderline significance in all cancers but significant in NSCLC (HR=1.36; 95% CI: 1.06–1.75).

Multiple testing correction was not applied because the analyses were hypothesis‐driven and limited to predefined anatomical subsites; therefore, findings with borderline significance should be interpreted cautiously. 5.

62.3±13.5, p=0.078) with borderline significance ( Table 4 ).

The borderline significance of some findings, such as the negative impact of DAPT on SCAD recurrence, should be interpreted cautiously.

Further prospective studies are necessary to clarify the kinematic variables with statically borderline significance and to define the long-term effects of surgical management for cervical anterior osteophytes.

Results Fasting and total AUC glucose in both tests were markedly higher in fGDM ( Table 1 ); fasting C-peptide was not different, while the dynamic C-peptide response to glucose stimulation only tended to be higher in fGDM, but only with borderline significance.

First, while of only borderline significance, our data essentially replicated the finding reported by Jukic et al.

We obtained only 2 significant DEPs, with borderline significance (Fig. 5C ).

The only study which specifically addressed the link between the basal serum AA levels and long-term prognosis in HNC patients concluded that increased serum levels of methionine had a favourable prognostic impact in terms of overall survival (OS) and relapse-free survival, while increased serine showed borderline significance as a negative prognostic factor for OS [ 15 ].

A retrospective Swedish study of newly diagnosed RRMS patients reported that rituximab was superior to all other DMTs in terms of drug discontinuation and had better clinical efficacy (rate of clinical relapse and/or disease activity on MRI) compared to injectable DMFs and borderline significance compared to natalizumab and fingolimod [ 128 ].

The analysis showed that the drug “was associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes that had borderline significance”, a finding not reported in published trials [20] .

In the case of the male gender, only borderline significance was achieved upon examination of the inverse non-linear relation between nut or peanut consumption and rectal cancer risk [ 27 ].

Using a fold change threshold of > 2.0 for significant upregulation and 1.8–2.0 for borderline significance, a total of 7 immune-related genes were significantly upregulated (fold change > 2.0), including Tlr7 (4.64), Tlr9 (3.04), Mpo (2.59), Tyk2 (2.57), Stat1 (2.13), Tlr6 (2.05), and Irf7 (2.03).

In the multivariate logistic regression model adjusted for age and sex (OR 0.43 (0.16–1.16), P = 0.094) as well as after adjustment for age, sex and comorbidities (OR 0.42 (0.15–1.17), P = 0.096) the association demonstrated a trend towards lower risk for in-hospital death in PE + Syncope patients by the administration of systemic thrombolysis with a borderline significance level, respectively.

The risk of re-infection when comparing 0 clones with 1 clone was not significantly different, however ≥2 clones was associated with an increased risk of re-infection with borderline significance (OR = 1.97 95% CI 0.99–3.93 by logistic regression) ( Table 3 ).

After adjusting for covariables, participants performing WFH during social distancing showed three-fold significantly higher odds of screen time and accumulated sitting time greater than eight hours a day and 29% higher odds (with borderline significance) of high domestic physical activity (OR = 1.29, 95%CI: 0.99–1.67) compared to those not performing WFH.

For topical 5-ASA/Steroid, MMP3 and HP show borderline significant changes which result in borderline significance for differentiating non-IBD ( Supplemental Table S7 ).

Furthermore, the NT-4 levels were higher, with borderline significance.