“borderline significance”

Similarly, at two weeks postintervention, the reduction in exertion after commencement of activity has borderline significance in favour of group 1.

However, the most likely explanation of this discrepancy is purely technical: only three I/St mice in appreciable health condition were available at this time point, which strongly increased statistical straggling, resulting in P = 0.057, i.e., borderline significance. 4.

These analyses increased the evidence of association for a number of additional loci that had shown borderline significance in the original US/SWE GWAS ( Table 3 ), including CFB , C12ORF30 , SH2B3 , and IL12B .

However, p -values indicated borderline significance for several models, and the ROC AUC values showed moderate discriminatory power, with the highest AUC of 0.612 for both LR and CatBoost.

There was no statistically significant difference in the hazard for our primary endpoint using random-effects Cox modelling, but the hazard of all-cause mortality and reinfarction did reach borderline significance with fixed-effect Cox modelling.

However, these associations fell into borderline significance with additive adjustments of sex and age.

[ 26 ] showed that the TT genotype of TLR9 (rs352140) displayed borderline significance in increased risk for advanced cervical cancer in a North India population.

On the other hand, several of our predictors showed borderline significance in the logistic regression model, which can either be a random finding, or the result of a too small sample size to detect an actual difference (type II error).

In an institution-clustered GEE model with robust standard errors, point estimates were directionally consistent with the primary model; stenosis at C3/4 remained significant (OR 2.13, 95% CI 1.38–3.29), and the association for posterior decompression and fusion was attenuated to borderline significance (OR 2.71, 95% CI 0.99–7.44) (Supplementary Table S2).

In stratified analysis, we found that the inverse association between hPDI and NAFLD seemed stronger in non-Hispanic whites than in others, with borderline significance ( p interaction = 0.009, Figure 2 ). 4.

It is worth mentioning that for glucose and insulin, the association detailed in this cohort shows borderline significance and type 2 error cannot be excluded.

One additional locus ( MCF2L [ENSG00000126217]) which only showed borderline significance here was recently reported to correlate with DNAm at cg05972352 in the study by de Witte et al.

This is reflected in the borderline significance seen for most findings and the fact that only the two most influential variants remained significant after FDR correction.

The seventh showed borderline significance (RR, 1.7; 95% confidence interval [95% CI], 1.0 to 2.8) but also provided evidence for a dose-response association with more severe periodontal disease being associated with the strongest risk of preterm birth (RR, 2.0; 95% CI, 1.3 to 2.9).

In contrast, rheumatoid factor, anti-CCP, ADMA, homocysteine, NT-proBNP, anti-dsDNA, and TNF-alpha showed borderline significance or inconsistent results.

Furthermore, ECOG performance status of 0–1, tumor of 10 cm in size or lower and any resection of tumor showed borderline significance with regard to superior EFS.

The limited power to detect interaction effects (1 − β = 0.53) may have contributed to the borderline significance observed.

Under Cox regression hazard (multivariate) analysis, factors associated with shorter OS were older age at treatment start, higher WBC counts (borderline significance), higher BM blasts, worse WHO-defined performance status, achievement of MiR or no response, shorter interval between initial diagnosis and lenalidomide treatment start, and complete transfusion dependency at baseline ( Table 6 ). 3.9.

For arterial stiffness, participants with LBW consistently had greater arterial stiffness in young adulthood ( P = 0.23) and mid‐adulthood ( P = 0.19), with borderline significance, than those in the NBW group.

The presence of one coronary sinus lead (OR = 1.189; p = 0.052) had borderline significance.

For female breast cancer, borderline significance was shown for the linear association.

The data showed that SAP2 and ECE1 expression significantly correlated, though with a moderate strength, to the NLRP3 inflammasome expression, while SAP6 had a borderline significance and SAP5 no statistical significant correlation at all with NLRP3 .

Specifically, the E/e′ ratio showed no difference (MD = 0.00; p = 0.99), while the differences in RVEF and sPAP demonstrated borderline significance, with p-values of 0.08 and 0.29, respectively.

In contrast, nationality showed a borderline significance for Saudis compared to non-Saudis (AOR: 7.06), though it did not reach statistical significance.

However, COX-2 expression predicted survival at borderline significance in a larger patient material [ 2 ].