“borderline significance”

Moreover, in a nest case–control study, ALP in type 2 diabetes seemed to be associated with CVD risk and stroke incidence in men, but with borderline significance [ 10 ].

A p-value threshold of 0.2 was selected to minimize the exclusion of potentially meaningful predictors with borderline significance.

While one mutant allele for Ptip exhibited no significant increase in Svp-lineage asymmetric cell division defects over the control, the other Ptip mutant displayed merely borderline significance.

A small sample size might have failed to prove a correlation between certain variables that showed borderline significance and a larger sample size may help to validate the results.

The aORs for usual stress (aOR 1.32, 95% CI 1.21–1.42), depressive mood (aOR 1.14, 95% CI 0.99–1.31; borderline significance), and suicidal ideation (aOR 1.17, 95% CI 1.05–1.30) were significantly higher among FwSS than GwoSF.

In multivariate analysis only younger age and lower HMW adiponectin concentration (with borderline significance) were risk factors for serum TXB 2 above the median (Table 5 ).

Although with borderline significance, the OR was below unity for the last two size categories.

As discussed above, we may have been underpowered to detect small effects of AKI on changes in these urine biomarkers, but none of the biomarkers showed AKI-associated changes of even borderline significance (Table 3 ).

The fixed-effects pooled OR was 1.17 [95% CI: 0.98–1.39, p = 0.075], showing only borderline significance for A allele carriers to have an altered risk of bone loss compared to non-carriers.

Verrengia and colleagues in Italy, studying a cohort of 36 patients with stage III EC, showed that optimal cytoreduction was a prognostic factor for OS and that adjuvant CT with RT seems to decrease the risk of recurrence but only with a borderline significance in OS [ 11 ].

This borderline significance likely stems from the limited number of studies included (only three).

Differentially expressed genes between T-cells isolated at baseline/early atherosclerosis and advanced stages ( Figure S12A ; Table S11 ) as well as between asymptomatic and symptomatic carotid plaques ( Figure S13B ; Table S11 ) were examined for enrichment in the 135 STARNET tissue-specific GRN but were not found to be significant (false discovery rate [FDR]>10%), besides a borderline significance of the macrophage-subcluster enriched GRN122 (Figure 6 ).

pN-stage lost significancy once the other LN-related variables were included in the models while pT3-4 disease still exhibited borderline significance.

Significance was determined by p -values below 0.05 and borderline significance was determined by p -values less than 0.10.

Year also had a significant effect on the ω-gliadin and LMW-GS contents and on the Gli/Glu ratio, and a borderline significance on total gliadin and HMW-GS contents (Table 1 ).

We found no association between most of the environmental exposures and risk of developing hemorrhagic stroke except positive associations with NO x and CO at a borderline significance level.

Age retained borderline significance (2 % decrease in risk of delayed or failed care linkage for each year increase in age; 95 % CI 0–5 %).

Again, it is likely that missing data and the choice to conduct a complete case analysis contributed to the borderline significance, given that n = 329 for Model 8.

These results are exploratory and require further investigation due to their borderline significance.

Lysine degradation was consistently impacted across all treatments (borderline significance for fluoxetine, FDR = 0.058), suggesting alterations in amino acid catabolism and mitochondrial function.

Interestingly, further stratification analysis grouped by spirometry-diagnosed COPD status revealed that the variant rs8040868C (CT + CC) genotypes exerted a protective effect against severe emphysema with borderline significance (OR =0.41, 95% CI =0.16–1.05) and affected the mean lung density, emphysema index, ratio of airway wall thickness to airway dimensions (AWT/AD), and AWT grade in spirometry-diagnosed non-COPD subjects.

For P-values at the borderline significance level (0.04–0.05), this study applied the False Discovery Rate (FDR) correction.

Receipt of Vitamin C or a multivitamin was associated with increased survival with borderline significance in both unadjusted and adjusted models (AOR = 3.52, CI:0.99–12.67).

Two subspecies of ceramides (CerP d26:0, Cer d18:1/24:1) were downregulated yet with borderline significance Figure 5 and Supplementary Table S2 ).

Examination of cortisol: ACTH ratio revealed a significant ratio reduction in PTSD vs TCs, and borderline significance when compared to HCs, a finding accentuated between 07:00 and 08:00 am, i.e. the cortisol awakening response and natural circadian peak.