“borderline non-significant”

When we analysed the proportional hazard assumption for the one-year risk of primary outcomes in patients who discontinued OAC compared to those who maintained OAC after PSM, we found potential non-proportional hazards for all-cause death (χ 2 10.834), and MACE (χ 2 25.283), with borderline non-significant values for major bleeding (χ 2 3.770) ( Fig. 3 ).

For example, the executive summary of the DWP-1 evaluation states, despite a primary outcome borderline non-significant at the 10% level, that the intervention was a success ( Table 2 , Quote 9).

Four months after baseline, lower difficulty scores of tasks underlying the umbrella goal ‘Feeling fit’ revealed a similar pattern; however, this change was borderline non-significant.

The OR for active cancer was lower in 2020 than 2019 but the difference was borderline non-significant (aOR3: 1.62 (1.55–1.70) in 2020 versus 1.78 (1.69–1.86) in 2019).

CKD, rheumatoid arthritis, and vitamin D insufficiency demonstrated borderline non-significant trends.

However, when the analyses were adjusted for cardiorespiratory fitness, the relationship between gray matter volume and academic achievement was borderline non-significant, suggesting a role of fitness in modulating brain development in different metabolic phenotypes, that, due to the lack of similar studies, needs to be further explored.

Three studies 1 , 22 , 24 reported sICH, with a borderline non-significant higher risk among patients with no-reflow (RR 1.88, 95% CI 1.00–3.56; I 2 = 0.0%; Figure 5(b) ).

By comparison, HbA1c measures indicated high risk in n = 24 (17%) of 139 participants at baseline and borderline non-significant changes over time in the randomised groups.

The exclusion of participants taking beta-blockers at baseline had little effect on the association between PACs and AF and between PVC and HF, but it slightly attenuated the association between PACs and HF (HR = 1.40, 0.97–2.02, P = 0.07) and between PVC and LTVA (HR = 1.71, 0.99–2.93, P = 0.052), which both became borderline non-significant (see Supplementary material online , Table S7 ).

Patients who were treated in a hospital with a stroke unit had a borderline non-significant reduced risk of death up to seven days after admission (OR: 0.57; 95% CI 0. 28, 1.15) when compared to patients who were treated in a hospital without a stroke unit.

Male sex (RR = 1.38, CI: 0.97-1.96), unawareness of twin pregnancy (RR = 1.64, CI: 0.97-2.78) and high blood pressure during pregnancy (RR = 1.77, CI: 0.88-3.57) were borderline non-significant.

The relationship between total SSBs sales volume and adult T2D burden was strongest in Kenya (β = 0.49, 95% CI: 0.29 to 0.69, p = 0.046), with consistent borderline non-significant positive associations also observed in South Africa, Morocco, and Ethiopia ( Figure 2 ).

In the head-to-head analysis, which included nine study arms from publications comparing more than one pacing technique, the adjusted overall effect was SMD = −0.10 (95%CI: −0.20 to +0.01; p = 0.063), which was borderline non-significant.

Analysis of the results by sex revealed that for men, there were no significant differences in intakes of total fat, mono- and polyunsaturated fats, omega 3 fatty acids, sugar, and alcohol, in addition to borderline non-significant differences for carbohydrates and saturated fats ( Appendix Table A ).

Bootstrap 95% CIs included unity at most time points; notably, the upper bound of the CI for HEMS mission time at 60 min crossed unity (upper bound 1.02), indicating a borderline non-significant result that should not be over-interpreted as a protective effect.

Since 2010, the upward trend has leveled off to borderline non-significant levels; however, in 2023, the proportion reached a historic peak, with preterm and/or LBW neonates accounting for 15.28% of all live births in the country.

The shift is borderline non-significant for 12,13-diHOME but significant for LA (Supplementary Data 3A ).

The borderline non-significant intercept term and slope coefficient for UKPDS 82 indicated a slight improvement in fit compared to UKPDS 68.

In the sensitivity analyses with grace periods of 30 and 90 days, female patients receiving their first CSA prescription by a rheumatologist were also at a reduced risk of CSA discontinuation ( Supplementary eTable S8 and Supplementary eTable S9 ), while the result was borderline non-significant in the main analysis (HR = 0.75, 95% CI: 0.55–1.01).

The higher risk of diabetes among those reported at least 10 h per day sleep (as compared to those reported 7 h of sleep per day) became borderline non-significant after adjustment for all potential confounders, suggesting that the association and underlying mechanisms between sleep duration and diabetes remain undetermined.

With regard to the neutralizing antibody titers, the following results were observed ( Table 2 ): 1) for the Alpha variant, there was a negative association with age and smoking, although this did not reach statistical significance; 2) for the Beta variant, there was a borderline non-significant negative association with smoking habit; and 3) for the wild-type variant, there was no association.

There was a borderline non-significant difference in mental distress between those that had a knee problem and those that did not; the percentage meeting the threshold for mental distress on the HSCL-10 was 21% (21/100) of those with knee problems and 12.4% of those without knee pain (26/209) (p = 0. 0.052; OR 1.9 95% CI 1.0 to 3.5) (Table 1 ).

GLMM-based sensitivity analysis corroborates the primary results, indicating a borderline non-significant protective effect of biological augmentation against conversion to THA.

Due to small numbers, the influenza B analysis yielded statistically borderline non-significant point estimates ( Table 2 ).

Only SYK was down-regulated (log 2 fold-change −2.7) and BTK showed a borderline non-significant tendency towards down-regulation (log 2 fold-change −2.0) in probable T-cell lymphomas.